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Mamatha T. Shenoy Benedicta D’Souza Lalesh Naik Akshatha Vivian D’Souza Madan Gopal Rajan 《Indian journal of clinical biochemistry : IJCB》2015,30(3):360-362
Tumor lysis syndrome has been observed in patients with malignancies with high cellular burden and high cell turnover, tumor sensitive to therapy, especially after initiating medical treatment. It very rarely occurs spontaneously. The case described here is of 6 months male infant who presented with fever since 1 month and loose stools associated with blood since 15 days. The laboratory investigations showed lactate dehydrogenase (LDH) of 6,192 IU/L and serum uric acid 18.2 mg/dl along with pancytopenia. The infant presented with electrolyte abnormalities and renal failure. 相似文献
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P.V.K. Sasidhar P. Gopal Reddy 《The Journal of Agricultural Education and Extension》2013,19(4):387-407
Abstract Purpose: The purpose of this study was to identify and rank the SWOT issues of India's veterinary and animal science education. Design: The data were collected at the Indian Veterinary Research Institute (IVRI) from 168 post-graduate students. The two surveys generated 72% (N=121) and 68% (N=114) response rates, respectively. In the first stage, the vital SWOT issues were listed by respondents and in the second stage, they ranked the top eight issues on a Likert scale. Findings: Uniform curriculum; merit-based admissions; and huge demand and employment prospects were perceived as major strengths. Gaps in curriculum revision and inadequate faculty, colleges and hands-on experience were perceived as key weaknesses. Regular curriculum revisions; novel instructional methods; and single admission tests were important opportunities perceived. Out-dated education model; urban biased admissions; and regional barriers were the major threats perceived. Practical implication: The SWOT issues identified are similar to those faced by veterinary education programmes in many countries with minor variations. Originality/value: The findings are of interest for veterinary faculties in developing and under-developed countries to harmonize their veterinary education systems on par with global norms. The related implications for policy and future directions are discussed. 相似文献
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The growing field of miniaturized diagnostics is hindered by a lack of pre-analysis treatments that are capable of processing small sample volumes for the detection of low concentration analytes in a high-throughput manner. This letter presents a novel, highly efficient method for the extraction of low-molecular weight (LMW) proteins from biological fluids, represented by a mixture of standard proteins, using integrated microfluidic systems. We bound a polydimethylsiloxane layer patterned with a microfluidic channel onto a well-defined nanoporous silica substrate. Using rapid, pressure-driven fractionation steps, this system utilizes the size-exclusion properties of the silica nanopores to remove high molecular weight proteins while simultaneously isolating and enriching LMW proteins present in the biological sample. The introduction of the microfluidic component offers important advantages such as high reproducibility, a simple user interface, controlled environment, the ability to process small sample volumes, and precise quantification. This solution streamlines high-throughput proteomics research on many fronts and may find broad acceptance and application in clinical diagnostics and point of care detection. 相似文献
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In the recent years, two significant changes have taken place in an effort to address rural poor: Businesses have started recognizing potential of rural markets and governments have started using telecenters for providing G2C services to rural citizens. In India, the national and sub-national governments have supported businesses to establish telecenters in rural areas to provide information technology enabled services. However, the focus so far has been mostly on B2C services and viability of telecenters is being questioned. We argue that sustainability of these centers can be enhanced considerably if government services are embedded. Also, designing these telecenters with embedded G2C services would significantly improve effectiveness of their delivery and strengthen government information network, to foster inclusive growth. 相似文献
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Machining titanium is one of ever-increasing magnitude problems due to its characteristics such as low thermal conductivity, modulus of elasticity and work hardening. The efficient titanium alloy machining involves a proper selection of process parameters to minimize the tangential force （Fz） and surface roughness （Ra）. In the present work, the performance of PVD/TiA1N coated carbide inserts was investigated using response surface methodology （RSM） for turning Ti-6A1-4V. The effects of process parameters such as speed （v）, feed （/＇）, depth of cut （d） and back rake angle （Ty） on Fz and Ra were investi- gated. The experimental plan used for four factors and three levels was designed based on face centered, central composite design （CCD）. The experimental results indi- cated that Fz increased with the increase in d, f and decreased with the increase in v and yy, whereas Ra decreased with the increase in v and 7y, and increased with d and v. The goodness of fit of the regression equations and model fits （R2） for Fz and Ra were found to be 0.968 and 0.970, which demonstrated that it was an effective model. A confirmation test was also conducted in order to verify the correctness of the model. 相似文献
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E. S. R. Gopal 《Resonance》2001,6(5):16-28
The new millennium started quietly on the 1st of January 2001, unlike the wide publicity given to the Y2K problem last year. The evolution of the concepts of months and years as well as the ideas of the calendar, culminating in the present Gregorian calendar, is described. Some anomalies are also discussed, showing clearly that scientific logic must necessarily coexist with popular perceptions. 相似文献
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E. S. R. Gopal 《Resonance》2000,5(4):37-45
Critical opalescence is a striking light scattering phenomenon, which was elegantly explained by Einstein. In the critical
region the light scattering is so large that the substance appears milky white in reflected light and brownish dark in transmitted
light. The phenomenon arises from the large fluctuations in the critical region of the substance. 相似文献