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1.
This study explored the factors affecting repeat theatrical viewing of movies. Integrating content, social influence, and access/competition variables, the analysis reveals that the drivers of theatrical repeat viewing are different from those for box office performance. For example, the effects of genre, transmedia content, and audience review were significant only for the latter and factors such as movie length, critics’ review, and level of news coverage actually played a negative role in the repeat consumption. 相似文献
2.
Jeong Ah Kim Hong Nam Kim Sun-Kyoung Im Seok Chung Ji Yoon Kang Nakwon Choi 《Biomicrofluidics》2015,9(2)
We present an engineered three-dimensional (3D) in vitro brain microvasculature system embedded within the bulk of a collagen matrix. To create a hydrogel template for the functional brain microvascular structure, we fabricated an array of microchannels made of collagen I using microneedles and a 3D printed frame. By culturing mouse brain endothelial cells (bEnd.3) on the luminal surface of cylindrical collagen microchannels, we reconstructed an array of brain microvasculature in vitro with circular cross-sections. We characterized the barrier function of our brain microvasculature by measuring transendothelial permeability of 40 kDa fluorescein isothiocyanate-dextran (Stoke''s radius of ∼4.5 nm), based on an analytical model. The transendothelial permeability decreased significantly over 3 weeks of culture. We also present the disruption of the barrier function with a hyperosmotic mannitol as well as a subsequent recovery over 4 days. Our brain microvasculature model in vitro, consisting of system-in-hydrogel combined with the widely emerging 3D printing technique, can serve as a useful tool not only for fundamental studies associated with blood-brain barrier in physiological and pathological settings but also for pharmaceutical applications. 相似文献
3.
Jeonghun Nam Justin Kok Soon Tan Bee Luan Khoo Bumseok Namgung Hwa Liang Leo Chwee Teck Lim Sangho Kim 《Biomicrofluidics》2015,9(6)
A novel microfluidic device which consists of two stages for particle focusing and separation using a viscoelastic fluid has been developed. A circular capillary tube was used for three-dimensional particle pre-alignment before the separation process, which was inserted in a polydimethylsiloxane microchannel. Particles with diameters of 5 and 10 μm were focused at the centerline in the capillary tube, and the location of particles was initialized at the first bifurcation. Then, 5 and 10 μm particles were successfully separated in the expansion region based on size-dependent lateral migration, with ∼99% separation efficiency. The proposed device was further applied to separation of MCF-7 cells from leukocytes. Based on the cell size distribution, an approximate size cutoff for separation was determined to be 16 μm. At 200 μl/min, 94% of MCF-7 cells were separated with the purity of ∼97%. According to the trypan blue exclusion assay, high viability (∼90%) could be achieved for the separated MCF-7 cells. The use of a commercially available capillary tube enables the device to be highly versatile in dealing with particles in a wide size range by using capillary tubes with different inner diameters. 相似文献
4.
Nam Cao Hoai Le Murat Gel Yonggang Zhu Jian Wang Helen Dacres Alisha Anderson Stephen C. Trowell 《Biomicrofluidics》2014,8(6)
Bioluminescence resonance energy transfer (BRET) is a form of Förster resonance energy transfer. BRET has been shown to support lower limits of detection than fluorescence resonance energy transfer (FRET) but, unlike FRET, has not been widely implemented on microfluidic devices for bioanalytical sensing. We recently reported a microscope-based microfluidic system for BRET-based biosensing, using a hybrid, high quantum-efficiency, form of BRET chemistry. This paper reports the first optical fiber-based system for BRET detection on a microfluidic chip, capable of quantifying photon emissions from the low quantum-efficiency BRET2 system. We investigated the effects of varying core diameter and numerical aperture of optical fibers, as well as varying microfluidic channel design and measurement conditions. We optimized the set-up in order to maximize photon counts and minimize the response time. The optimized conditions supported measurement of thrombin activity, with a limit of detection of 20 pM, which is lower than the microscope-based system and more than 20 times lower than concentrations reported to occur in plasma clots. 相似文献
5.
Younkyeong Nam Gillian Roehrig Anne Kern Bree Reynolds 《International Journal of Science and Mathematics Education》2013,11(1):143-167
This study explores the perceptions of culturally relevant science teaching of 35 teachers of American Indian students. These teachers participated in professional development designed to help them better understand climate change science content and teaching climate change using both Western science and traditional and cultural knowledge. Teacher perceptions of practices using culturally relevant instruction were evaluated. The data were analyzed both quantitatively and qualitatively. The results from the survey analysis show that the teachers’ existing practices of culturally relevant science teaching were limited in choosing topics relevant to American Indian culture. We found three common themes from the teachers’ perceptions of culturally relevant science teaching, meaning of culturally relevant science teaching, teaching strategies, and purpose of culturally relevant science teaching from the qualitative data. We also found that teachers with higher survey scores perceive culturally relevant science teaching differently than teachers with lower survey scores, specifically for the purposes and teaching strategies of culturally relevant science teaching. The results show that teachers with higher survey scores tended to perceive culturally relevant science teaching as a two-way learning process between teachers and students where the teachers can learn traditional science knowledge from the students. They also tend to perceive using concrete traditional science examples as effective teaching strategy for culturally relevant science teaching and building strong relationships with American Indian students as the most important purpose of culturally relevant science teaching. We also discuss common challenges faced by science teachers when trying to implement culturally relevant science teaching with American Indian students. 相似文献
6.
Early Malnutrition and Child Neurobehavioral Development: Insights from the Study of Children of Diabetic Mothers 总被引：2，自引：0，他引：2
In this study we sought to discern whether disturbances in mothers' metabolism during pregnancy may exert long-range effects on the neurobehavioral development of the progeny. Participants were 139 Women with diabetes in pregnancy and their singleton offspring. Serial estimates of circulating maternal fuels were obtained for each pregnancy, along with detailed records of perinatal course and outcome. Offspring were administered the Wechsler Intelligence Scale for children—Revised (WISC-R) full-scale IQ scores below 70 in our cohort did not differ significantly from national estimates. Nonetheless, after statistically controlling for other influences, WISC-R verbal, performance, and full-scale IQ scores, and Bannatyne's indices of Verbal Conceptualization Ability, Acquired Knowledge, Spatial Ability, and Sequencing Ability were inversely correlated with measures, of maternal lipid and glucose metabolism in the second and third trimesters. KTEA Arithmetic scores were similarly correlated with measures of maternal lipids in the third trimester. All correlations indicate that poorer metabolic regulation was attended by poorer child performance. The effects of maternal metabolism on fetal brain and neurobehavioral development are discussed as potential intermediary factors. 相似文献
7.
Sang‐Joon Nam 《Environmental Education Research》1995,1(1):109-122
In the past, environmental education in Korea was not effective, in part at least, because it was not dealt with as an independent subject. However, in the Sixth Curriculum for schools in Korea, which will take effect from 1995, ‘Environment’ subject is included as an optional course for junior high school students. This paper gives details of the curriculum of ‘Environment’ subject and describes the development of the course textbook which focuses on values and attitude change. The paper also discusses Ministry of Education plans for teacher education and training courses for teachers of the new subject. Despite the current lack of qualified teachers for the subject and the fact that it is not mandatory, the introduction of the ‘Environment’ subject in the national curriculum is seen to be of great significance. With rapidly increasing national concern about environmental issues, and with an increasing number of schools teaching ‘Environment’ subject, it is expected that environmental education in Korea will move more efficiently and profoundly towards realizing its ultimate purpose. 相似文献
8.
沪港澳中学数学课堂的主要共性有:指令性讲解为主;较为重视课堂练习;强调问题之间的内在联系;强调讲清概念;强调对算法的讲解、练习以及总结.主要差异有:上海课堂的效率最高,并有一定时间为学生提供探究性学习的机会;香港课堂练习时间最多,但练习的问题中,重复性和低复杂性的问题最多;澳门课堂练习时间最少,而练习的问题复杂性较高等. 相似文献
9.
AbstractThis paper introduces ‘Integrative Drama-Inquiry Learning’ (IDI), merging drama-based learning with inquiry-based learning in order to exemplify teaching science through drama. The study also reports on the findings of a sequential mixed-methods procedure embedded in a quasi-experimental research design aimed to understand the effects of IDI on middle school students’ achievement in a biological unit. The initial quantitative phase revealed that IDI instruction had a significant effect on the experimental group’s achievement compared with traditional teaching. A follow-up qualitative phase showed that their achievement was affected by the enhancement of intrinsic motivation through IDI. Analysis suggested that students’ satisfaction of psychological needs of competency, relatedness, and autonomy positively affected learners’ motivation, as advocated by the self-determination theory. 相似文献
10.
Soon Nam Kim 《Asia Pacific Education Review》2005,6(1):41-49
The purpose of this paper is to inquire into the developmental directions and tasks of the School Based Curriculum Management(SBCM)
system. The concept of the School Based Curriculum Management can be considered as a subsystem to School Based Management.
The logics behind the SBCM system are autonomy, accountability, effectiveness, creativity, professionalism, and participation.
The developmental directions of SBCM are to establish and implement the highly autonomous and participative SBCM, the diverse
creative SBCM, the highly accountable SBCM, and the professional SBCM. The developmental tasks of SBCM suggested in this study
are to establish the School Based Staff Development system, to practice the evaluation system that can control the quality
of SBCM, to be managed by a strategic-layer management system, and to constitute the committee of school curriculum. 相似文献