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Cherian George 《The Communication Review》2013,16(3):247-268
The Internet has become a medium for contentious political journalism in Malaysia and Singapore, two countries known for their enthusiastic adoption of information technologies as well as their illiberal controls on political expression. These alternative sites inhabit a regulatory gap within an otherwise closed media system. Internet laws in these two settings provide a degree of freedom that is significantly greater than experienced in print and broadcast media. This article tries to explain this anomaly. It argues that the Internet’s perceived economic value dominated the authorities’ policy formulation, subordinating the goal of political control that historically shaped media policy. When dealing with print and broadcast media, the authorities had been able to tailor their political interventions narrowly, such that these actions did not smother their economic priorities. In contrast, the Internet was not as amenable to narrow tailoring. The two governments decided to tolerate a lesser degree of political control than that to which they were accustomed. While the governments maintained the prerogative to mete out after-the-fact punishments against any offending Internet publication, they were less capable of imposing prior restraints or encouraging self-censorship-their more routine forms of media control. It is not argued that the resulting advantage for radical journalism was either absolute or permanent, only that it presented a sufficiently attractive opportunity for action. 相似文献
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G Broadley KM Broadley 《Educational research; a review for teachers and all concerned with progress in education》2013,55(3):259-268
In New Zealand, school principals (headteachers), sometimes with a sub-committee of the school board of trustees, interview and hire their own teachers. This research examined whether school principals exhibit different styles in recruiting beginning teachers. A small group of principals was interviewed and items reflecting their views were then developed and put on cards. The cards were sorted by people familiar with educational vocabulary to enable category setting using Kirkland and Bimmler's GOPA technique. Seventy-one principals then prioritized the items. A k-means algorithm was used to cluster principals with similar responses. Analysis of the clusters suggests that recruiting styles do exist. General compatibility emerged as being most important. This suggests that having schools appoint their own staff may lead to greater diversity between schools and greater conformity within them. 相似文献
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The categorization performance of monkeys on a unidimensional perceptual categorization task was examined with reference to
decision bound and exemplar theories of categorization. Three rhesus monkeys were presented with stimuli varying along a single
dimension, the displacement of a target light from a fixation point. Left or right saccade responses were probabilistically
reinforced according to one of three functions, two of which were nonmonotonic at one end of the stimulus space. The monkeys
all showed a monotonic increase in response probability as a function of target light displacement in this region, consistent
with decision bound theory. Fits of a single-boundary model (GRT; Ashby & Gott, 1988) and two exemplar models—one using a
probabilistic response function (GCM; Nosofsky, 1986), the other using a deterministic response function (DEM; Ashby & Maddox,
1993)—revealed overall support for the decision bound model. The results suggest that monkeys used a perceptual decision boundary
to perform the task. 相似文献
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Priya Gururajan Prema Gurumurthy Pradeep Nayar Sai Babu A. Sarasabharati Dolice Victor K. M. Cherian 《Indian journal of clinical biochemistry : IJCB》2009,24(3):229-233
CD40-CD40L interaction plays a significant role in the pathogenesis of atherosclerosis and coronary artery disease. The clinical
predictive value of Soluble CD40 Ligand (sCD40L) was evaluated in patients with Acute Coronary Syndrome (ACS) and Non-Cardiac
Chest Pain (NCCP). The levels of serum soluble CD 40 ligand were measured by ELISA in 485 patients admitted to emergency care
unit, of which 89 patients were diagnosed as NCCP. The levels of sCD40L were significantly increased in patients with ACS
when compared to controls and NCCP. Receiver Operator Characteristic (ROC) Curve analysis showed sCD40L to be a good discriminator
between patients with ischemic heart disease and patients without ischemic heart disease. The area under the curve was found
to be 0.940 with 95% CI (0.915 to 0.960) (P<0.0001). The cut off value from the ROC curve was 2.99 ng/ml, above which sCD40L
was considered to be positive. Combined assessment of sCD40L, Troponin I and CK-MB enhanced the risk prediction and early
classification of patients. sCD40L seems to be a promising biomarker for identification and risk stratification for patients
with acute coronary syndrome. 相似文献
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Srinivasa Nageswara Rao G Prema G Priya G Arumugam SB Kirthivasan V Saibabu R Cherian KM 《Indian journal of clinical biochemistry : IJCB》2011,26(1):22-27
There is a rising trend in the prevalence of insulin resistance among obese, overweight children and adolescents. The serum
insulin and its correlation with biochemical, clinical and anthropometric parameters were evaluated in 185 children and adolescents
(59 control, 52 obese, 49 overweight, 25 congenital heart disease) of age group 10–17 years. The levels of serum insulin were
measured by ELISA. Serum insulin levels were found to be significantly increased in children who were obese, overweight and
had congenital heart disease, than controls. Serum insulin levels positively correlated with BMI, WHR, and serum C-peptide,
serum leptin, total cholesterol, triglycerides, LDL-cholesterol, systolic and diastolic blood pressure. Fasting glucose levels
were found to be negatively correlated with serum insulin levels. HDL-cholesterol levels were non-significant among the study
groups. We identified nine obese children (five girls and four boys) with the features of metabolic syndrome and 69% of obese
and overweight children were identified with insulin resistance. Insulin resistance was strongly associated with metabolic
syndrome and its components, especially with central obesity and hypertriglyceridemia. 相似文献
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P. Subash Prema Gurumurthy A. Sarasabharathi K. M. Cherian 《Indian journal of clinical biochemistry : IJCB》2010,25(2):127-132
Establishment of non-invasive urinary biomarker for the early prediction of essential hypertension (EH) is important. We evaluated
whether estimation of urinary DNA, serves as a marker to predict the extent of cellular oxidative stress in essential hypertension.
A total of 180 South Indian subjects aged 30–65 were recruited for the study. Of these hypertensive subjects investigated,
30 were newly diagnosed and were not on any antihypertensive drugs, but had systolic blood pressure 140–160 mmHg and diastolic
blood pressure 95–100 mmHg and 75 hypertensive patients who already on drug therapy for one year and 75 were South Indian
normotensive healthy controls with blood pressure ≤ 120/80 mmHg. The 8-OHdG level in urine was significantly increased in
hypertensive patients (both newly diagnosed and who already on drug therapy) compared with control group. The significant
increase in 8-OHdG was observed in newly diagnosed hypertensive patients compared with hypertensive patients who already on
drug therapy. There was a significant decrease in serum TAS value in essential hypertensive group when compared to control
group. The urinary 8-OHdG was independently correlated with serum TAS. Decreased TAS levels, which reflect to increased oxidative
stress, may be the reason of increased urinary 8-OHdG in South Indian hypertensive patients. Our preliminary data suggest
that the competitive ELISA for 8-OHdG appears to be a simple method for quantifying the extent of oxidative stress. 相似文献
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Prema Gurumurthy Sai Krishna Borra Rama Krishna Reddy Yeruva Dolice Victor Sai Babu K. M. Cherian 《Indian journal of clinical biochemistry : IJCB》2014,29(3):367-371
Myocardial ischemia produces free radicals that catalyze a series of oxidative reactions that damage healthy tissues. The N-terminal sequence of albumin is one of the proteins modified by these highly reactive oxygen species and forms the ischemia modified albumin (IMA). This study involves investigations undertaken in different study groups to assess the levels of IMA. Mean serum IMA levels (U/mL) in patients with ST-segment elevated myocardial infarction (92.1 ± 10.6), non-ST-segment elevated myocardial infarction (87.3 ± 5.95) and unstable angina (UA) (88.9 ± 6.16) were significantly higher than non-cardiac chest pain (77.9 ± 6.69) and also healthy subjects (54.7 ± 17.2) (p < 0.001). IMA is a highly sensitive marker and has a high predictive value, which might prove the usefulness of this biomarker for early detection of myocardial ischemia. These data indicate a possible role of the IMA test in the early triage of patients with chest pain. 相似文献
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Maria Loftus Peter Tiernan Sebastian Cherian 《Education and Information Technologies》2014,19(3):569-582
Evidence has shown that students have greatly increased their consumption of digital video, principally through video sharing sites. In parallel, students’ participation in video sharing and creation has also risen. As educators, we need to question how this can be effectively translated into a positive learning experience for students, whilst examining how willing students actually are to critically engage with digital video and analysing how best to hone their digital literacy skills. Firstly, this article presents a cross-cultural analysis of Irish and Indian students’ perception of themselves as creators of digital video and examines their readiness to produce such videos as part of third level curricula. Secondly, it attempts to quantify the expose of both student cohorts to video sharing and creation. Thirdly, it analyses student perceptions of what challenges they face as they move from consumers to creators of digital video. Results indicate that whilst students are willing to adopt digital video for academic tasks, this article will analyse what supports and considerations need to be put in place in order for its successful integration in curricula. 相似文献
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