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High blood pressure (hypertension) is implicated in the development of atherosclerosis. Blood vessels are constantly subjected to stretch due to blood pressure and changes in stretch usually instigate adaptive vascular remodeling, including abnormal growth and proliferation of vascular smooth muscle cells (VSMCs) as well as 相似文献
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Cellular growth under hydrostatic pressure using bovine aortic EC-SMC co-cultured ePTFE vascular graft 总被引：1，自引：0，他引：1
High blood pressure (hypertension) is implicated in the development of atherosclerosis. Blood vessels are constantly subjected to stretch due to blood pressure and changes in stretch usually instigate adaptive vascular remodeling, including abnormal growth and proliferation of vascular smooth muscle cells (VSMCs) as well as extracellular matrix (ECM). In this experiment, we used bovine aortic endothelial cells and smooth muscle cells (EC-SMC) co-cultured ePTFE vascular grafts subjected to normal atmospheric pressure (as a control), and 100 mmHg hydrostatic pressure for 7 d. The increase of cell layer thickness was observed. When measured, the cell layer thickness increased by 116.2%. The increase of collagen (Type IV) synthesis was also observed in the immunohistochemistry assay. When stained with toluidine blue, the cells showed metachromatic phenomenon. 相似文献
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In this paper it is shown that a class of pursuit-evasion games can be treated more simply by the geometrical approach with the topological properties of the reachable region and by the method of functional analysis. Conditions for capture and optimal strategies are derived. A numerical example is given to show both the optimal open-loop strategies of players and the optimal trajectories of the game. 相似文献
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Koichi Toya 《Emotional and Behavioural Difficulties》2013,18(2):152-163
Abstract The Dohsa method is an effective therapeutic method used for children with autism which was developed originally for children with cerebral palsy in Japan. In this article, the author introduces the theoretical background, therapeutic techniques, and effectiveness of this method. Finally, the necessity of the combination of this method with other therapeutic techniques is discussed. 相似文献
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YUAN Bo MURAYAMA Koichi 《浙江大学学报(A卷英文版)》2007,8(2):171-175
INTRODUCTION The bands of near-infrared (NIR) spectra have low absorptivities, which allow in situ analysis of chemical and biological materials with no or little sample preparation. Therefore, as one of the most important nondestructive analytical techniques, NIR spectroscopy is being extensively applied in the fields of agriculture, industry, biotechnology and medicine (Siesler et al., 2002; Scarff et al., 2006; Ward et al., 2006). Recently, with instrumental developments such as Fou… 相似文献
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Toru Ishihara Toshihiro Nakajima Koichi Okita Koji Yamatsu Masato Sagawa 《European Journal of Sport Science》2018,18(2):286-294
The purpose of this study was to determine, using structural equation modelling (SEM), the direct and indirect influence of daily behaviours (i.e. exercise/learning durations), weight status, and physical fitness on academic performance among seventh-grade schoolchildren, after controlling for socioeconomic status. We analysed cross-sectional data from 274 schoolchildren (159 males and 115 females; 12–13 years old). Academic performance was assessed using the total grade points in eight academic subjects. Physical fitness was evaluated using the total score of eight physical fitness tests and weight status using body mass index. The daily behaviours and socioeconomic status were assessed by the questionnaire. The SEM showed an adequate fit to the data (χ2?=?0.684, p?=?.710, RMSEA?=?.000). Physical fitness and learning durations had direct effects on academic performance (β?=?.301, p?β?=?.132, p?=?.037, respectively) after controlling for confounders. Healthy weight status and exercise habits positively indirectly influenced academic performance via physical fitness. These findings suggest that, independent of socioeconomic status and learning durations, exercise habits and maintaining healthy weight status may indirectly contribute to academic success via better physical fitness in children. 相似文献
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Koichi Iwabuchi 《Inter-Asia Cultural Studies》2013,14(4):543-556
Abstract The 2003 film Lost in Translation has attracted both acclaim and critique concerning its representation of the urban imaginary of Tokyo. Examining both the film representation and the critical responses to the imaginary, this paper discusses how they illuminate some of the emerging issues that Tokyo and Japan face in the era of globalization, such as the loss of the idiosyncratic status of non‐Western modernity that Japan has long enjoyed; post‐(self)Orientalist cultural othering; and the transnational alliance of media and cultural industries in a global cultural economy of branding the nation through media and consumer cultures, all at the expense of the issue of intensifying migration and multicultural situations in the urban space. It will be suggested that both the film and Japanese critiques of the film are lost in the actuality of Tokyo (indeed, of Japan) and its populace, which is being radically transformed by intensifying transnational flows of people, capital, and media imagery. 相似文献
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The problem of time-optimal control systems with both norm constraints on control inputs and on state variables at discrete intermediate times is formulated as an L-problem in the theory of moments. The simplex method is used for solving a nonlinear minimizing problem inherent in the functional analysis solution to this latter problem. Numerical results are presented for a train operation. 相似文献
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