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The development of metabolic acidosis during cardio-pulmonary bypass (CPB) is a well recognized but poorly explained phenomenon.
It has been hypothesized that it is purely a development after the delivery of pump prime. A retrospective study was conducted
at our hospital on 68 patients who underwent elective coronary artery bypass grafting (CABG). Sampling of arterial blood was
performed at three time intervals: (T1) Baseline, prior to induction; (T2) 5 minutes after initiation of CPB and prior to administration of cardioplegia solution; (T3) during rewarming prior to weaning
the patient off CPB. Measurements of Na+, K+, Cl−, pH, pCO2, HCO3
−, Base excess, Anion gap, Strong ion difference at each collection point were performed. Results were analyzed in a quantitative
manner. On delivery of pump prime, all patients' developed metabolic acidosis. However, it is very important to distinguish
the metabolic acidosis as their management varies. Anion gap has been found to be useful in managing peri-operative metabolic
acidosis. 相似文献
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