排序方式： 共有11条查询结果，搜索用时 156 毫秒
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Lino J. Alvarez-Vázquez Francisco J. Fernández Aurea Martínez 《Journal of The Franklin Institute》2014
This work deals with an environmental problem related to controlling eutrophication inside a sensitive zone, by means of a regulation of the wastewater discharges in the region. After setting a detailed mathematical formulation of the optimal control problem posed on a free-boundary moving domain, we present several theoretical results on existence-regularity of optimal solutions, and their characterization by a first order optimality system. In the second part of the work a complete numerical algorithm for the resolution of the control problem is proposed, and several numerical examples are also given. 相似文献
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Mariana Biagi Batista Catiana Leila Possamai Romanzini Cynthia Correa Lopes Barbosa Gabriela Blasquez Shigaki Marcelo Romanzini Enio Ricardo Vaz Ronque 《Journal of sports sciences》2013,31(19):2253-2262
ABSTRACTThe aim of this study was to systematically review the literature to verify the association between participation in sports (PS) in childhood and adolescence and physical activity (PA) in adulthood. A systematic search was conducted in the following databases: Medline (PUBMED), Web of Science, Scopus, and SPORTDiscus, LILACS and SciELO. All steps of the process followed the recommendations of the PRISMA FlowDiagram. After all the steps of the process, 29 articles were included for analysis. In general, only three of the studies analyzed found no relation between PS in childhood and adolescence and PA in adulthood. However, a positive relationship was found to be weak in only 7% of the studies, a moderate relation in 62% of the studies, and a strong relation in 21%. It was found that higher weekly frequencies of PS; persistence of at least three years of PS and, finally, the highest level of practice and/or competition reached were related to higher levels of PA in adulthood. Thus, it can be concluded that there is a positive association considered moderate to strong between PS in childhood and adolescence and PA in adulthood. 相似文献
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Arathi Sriprakash Adam Possamai Ellen Brackenreg 《The Australian Educational Researcher》2014,41(3):227-242
This paper examines ideas of cosmopolitanism, particularly social theorists’ interests in a cosmopolitan ‘disposition’, to consider how religiously diverse students experience campus life in a multi-faith Australian university. We draw on data from focus-group interviews conducted with students from Muslim, Christian, Spiritual, and Atheist student-groups to contribute empirical insights into theoretical debates about cosmopolitanism. We show how students understand religious relations in a university campus in multiple ways; moving back and forth between relations of religious openness and tension in different institutional scenarios. In light of these findings, we reflect on the possibilities of fostering ‘cosmopolitan religiosity’ in higher-education settings and demonstrate the limits of a liberal multicultural approach to religious diversity. 相似文献
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Adam Possamai Kevin Dunn Peter Hopkins Lisa Worthington Faroque Amin 《Journal of Higher Education Policy & Management》2016,38(6):637-648
Although there has been much research about the growing ethnic and religious diversity on university campuses across the world, relatively little is known about the religious and cultural experiences of Muslim students on university campuses in Australia. We draw upon an analysis of a questionnaire that was completed by 323 Muslim students who were studying at universities in the state of New South Wales, Australia. While we argue that these places are post-secular, we discovered that city campuses tend to be more secular than regional and suburban ones. 相似文献
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K. Hockemeyer C. Janetopoulos A. Terekhov W. Hofmeister A. Vilgelm Lino Costa J. P. Wikswo A. Richmond 《Biomicrofluidics》2014,8(4)
Stromal cells in the tumor microenvironment play a key role in the metastatic properties of a tumor. It is recognized that cancer-associated fibroblasts (CAFs) and endothelial cells secrete factors capable of influencing tumor cell migration into the blood or lymphatic vessels. We developed a microfluidic device that can be used to image the interactions between stromal cells and tumor cell spheroids in a three dimensional (3D) microenvironment while enabling external control of interstitial flow at an interface, which supports endothelial cells. The apparatus couples a 200-μm channel with a semicircular well to mimic the interface of a blood vessel with the stroma, and the design allows for visualization of the interactions of interstitial flow, endothelial cells, leukocytes, and fibroblasts with the tumor cells. We observed that normal tissue-associated fibroblasts (NAFs) contribute to the “single file” pattern of migration of tumor cells from the spheroid in the 3D microenvironment. In contrast, CAFs induce a rapid dispersion of tumor cells out of the spheroid with migration into the 3D matrix. Moreover, treatment of tumor spheroid cultures with the chemokine CXCL12 mimics the effect of the CAFs, resulting in similar patterns of dispersal of the tumor cells from the spheroid. Conversely, addition of CXCL12 to co-cultures of NAFs with tumor spheroids did not mimic the effects observed with CAF co-cultures, suggesting that NAFs produce factors that stabilize the tumor spheroids to reduce their migration in response to CXCL12. 相似文献
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The name ambiguity problem is especially challenging in the field of bibliographic digital libraries. The problem is amplified when names are collected from heterogeneous sources. This is the case in the Scholarometer system, which performs bibliometric analysis by cross-correlating author names in user queries with those retrieved from digital libraries. The uncontrolled nature of user-generated annotations is very valuable, but creates the need to detect ambiguous names. Our goal is to detect ambiguous names at query time by mining digital library annotation data, thereby decreasing noise in the bibliometric analysis. We explore three kinds of heuristic features based on citations, metadata, and crowdsourced topics in a supervised learning framework. The proposed approach achieves almost 80% accuracy. Finally, we compare the performance of ambiguous author detection in Scholarometer using Google Scholar against a baseline based on Microsoft Academic Search. 相似文献
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Camprubí L 《Endeavour》2012,36(1):23-31
After the Spanish Civil War (1936-1939), Francisco Franco's emphasis on dam building became so intense that it is still today associated with his dictatorial rule. Rather than being purely a personal obsession, however, this intensive period of reservoir construction was the result of the influential political role played by engineers from the early years of the regime. During the years 1946-1961 some of these engineers undertook the 'total transformation' of the Noguera Ribagorzana river basin in the Catalonian Pyrenees. But this explicitly 'totalitarian' project encountered important limitations posed both by competing state agencies and by the basin's geology. Analysing the efforts of these engineers allows for new understandings of the Francoist regime and of the place of science, technology, and the landscape within it. 相似文献