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D. C. Sharma Gora Dadheech Bushra Fiza Meghna Mathur Manminder Riyat Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2009,24(2):202-204
Silver is ingested in India in the form of varak, Ayurvedic bhasm and water contained in silver utensils, but nobody knows
their effects. We have examined the effect of interaction of silver ingested in the form of varak (leaf), bhasm (ash) and
water (colloidal solution) on some essential elements (Na, K, Ca, Mg, Cu, Fe and Zn) in blood, liver, spleen and kidneys of
chicks. The results showed significant rise of silver in all the tissues and significant fall in copper in the blood. The
greatest rise was obtained in blood silver by silver sol while it had the lowest amount of silver. Iron significantly increased
in tissues but somewhat decreased in blood. Zinc content increased in all the tissues by leaf and ash but decreased by sol.
No consistent pattern was seen in case of other elements. 相似文献
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D. C. Sharma Bhawani Kochar Ankita Bhardwaj Manminder Riyat Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2009,24(3):245-249
In order to scientifically evaluate the effect of copper bhasm, it was orally administered in a dose of 2 mg/day for seven
days to one month old male chicks. There was significant fall in total red cells, and rise in plasma iron, PCV and MCV indicating
hemolysis, compensated by increased heme synthesis. A significant increase in plasma iron binding capacity points to beneficial
effect of copper bhasm on liver as transferrin is synthesized in liver. Ferritin (storage iron) was unaltered in seven days
treatment. The effect of copper bhasm on tissue distribution of essential elements was variable. Calcium, sodium and potassium
were significantly increased in all the tissues. The last two may have been contributed by the bhasm itself. Magnesium behaviour
was similar to calcium. Iron and zinc showed variable effects. Copper level in whole blood, plasma and erythrocytes increased
significantly showing that copper bhasm was well absorbed and the effect observed can be ascribed to it. The bhasm was well
tolerated and no growth retardation was seen. 相似文献
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Dinesh C. Sharma Deepa Chandiramani Manminder Riyat Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2007,22(2):123-128
A number of preparations are available in Ayurved for treatment of anemia and iron deficiency. This study was designed to
evaluate efficacy of some of them. Six most commonly used Ayurvedic iron containing preparations (Navayasa Curna, Punarnavadi Mandura, Dhatri Lauha, Pradarantaka Lauha, Sarva-Juara-Hara Lauha and Vrihat Yakrdari Lauha) were given in a dose of 250 mg b.d. for 30 days to six groups of iron deficient anemic patients; each group consisting of
20 patients. A control group was given Allopathic preparation—Irex-12, (containing—ferrous fumarate, vitamin C, folic acid
and vitamin B12); 1 capsule daily for 30 days for comparison. All hematological and iron parameters were determined before and after completion
of treatment. The results showed that there was statistically significant rise (p<0.001) in all of them—Hb, PCV, TRBC, MCV,
MCH, MCHC and plasma iron, percent saturation and plasma ferritin. Total iron binding capacity decreased significantly (p<0.001).
The response of most of Ayurvedic preparations was better than Allopathic preparation and there was no side effect as observed
with iron salts The Hb regeneration rate was 0.10 g/dl/day for Allopathic preparation; while it was above this value for all
Ayurvedic preparations exceptPradarantaka Lauha which was least effective.Sarva-Juara-Hara Lauha was the drug of choice as Hb regeneration with it was highest 0.16 g/dl/day. Upon analysis of Ayurvedic drugs, these results
were found to be consistent and correlated with iron content of the preparation. 相似文献
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