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The modern workplace environment is filled with interruptions due to the necessity of coworkers to communicate with each other. Studies have revealed that interruptions can impact task performance (TP). Communication interruptions are due, in part, to the unavoidable side-effect of using technology to facilitate these interactions. This experimental case study reports about an investigation we conducted on the role of instant messaging interruptions (IMI) and its implications on knowledge workers’ TP in a workplace environment. We have gathered data from knowledge workers engaged in an e-learning activity. The case study included a total of 60 experimental observations and analysis of the 120 records revealed that the time to complete a task (TPtct) for certain types of tasks, was significantly affected by IMI. This case study addressed gaps in IM interruption research and practical knowledge about the role of instant messages in the organization. Previous research has been conducted in a laboratory environment with interruptions generated by means other than actual IM. This case study used IMI with participants working in their normal workplace. Findings were used to provide a set of lessons learned recommendations for managers when it comes to the use of IM in the workplace.  相似文献   
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高等教育尤其是地方高等教育的转型升级与地方经济的转型升级二者相互联系、相互促进。广州建设国家中心城市及其经济转型升级需要科技教育文化的强力支撑,这既为广州市属本科高校的转型升级带来了巨大压力,也为其转型升级提供了强大的动力和支持。广州市属本科高校服务地方经济转型升级有着地域、定位、文化、信息、资源、成本等诸多有利条件和优势,但也存在办学层次偏低、办学定位存在偏差、多重结构性矛盾并存等障碍因素。因此,广州市属本科高校必须以服务地方经济转型升级为实现自身转型升级的目标取向,构建具有战略性特征与综合整体功能的人才培养体系、具有先进性特征与服务引领功能的学科及科研创新体系、具有前沿性特征与国际化功能的中外合作体系。  相似文献   
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In the era of the targeted therapy identification of EGFR mutation detection in lung cancer is extremely helpful to predict the treatment efficacy of EGFR tyrosine kinase inhibitors (TKIs). Unfortunately, the inadequacy and quality of the biopsy samples are the major obstacles in molecular testing of EGFR mutation in lung cancer. To address this issue, the present study intended to use liquid biopsy as the non-invasive method for EGFR mutation detection. A total of 31 patients with an advanced stage of lung cancer were enrolled in the study from which cell-free DNA (cfDNA) and FFPE tissue DNA was extracted. Extracted DNA samples were analyzed for further EGFR exon specific mutation analysis by ARMS-PCR. Data were analyzed statistically using SPSS software. In cfDNA samples, the prevalence of wild type EGFR was 48% while the prevalence of TKI resistant and TKI sensitive mutations were 3%. Conversely, in tissue DNA samples, the prevalence of wild type, TKI sensitive and TKI resistant mutations were 48%, 19%, and 3%, respectively. The overall concordance of EGFR mutation between cfDNA and tissue DNA was 83%. McNemar’s test revealed that there was no significant difference between EGFR expression of cfDNA and tissue DNA samples. Additionally, the significant-high incidence of TKI resistant mutations was observed in tobacco habituates, indicating the role of carcinogens present in the tobacco in developing resistant mutations. In conclusion, our data suggest that evaluation of EGFR mutation from cfDNA samples is practicable as a non-invasive tool in patients with advanced-stage of lung cancer.  相似文献   
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The present study set out to examine students’ preferences for lecturers’ personality as a function of their classroom behaviour, core self-evaluations and self-rated character strengths. Various hypotheses were tested: first, students’ Big Five traits would significantly predict corresponding personality preferences for lecturers (the matching hypothesis); second, students’ core self-evaluation scores would significantly predict preferences for extraverted, agreeable and conscientious lecturers; and third, self-rated character strengths would also significantly predict extraverted, agreeable and conscientious lecturers. We also investigated difference in preferences among two ethnic groups (South East Asian/Chinese versus Caucasian/British). In all, 264 British students completed four questionnaires. Conscientiousness was the most desired trait in lecturers, followed by agreeableness, extraversion and openness; neuroticism was the least desired trait. Preference for agreeable lecturers was best predicted by all individual difference variables. Caucasian students had a stronger dislike for neurotic lecturers, while Asians had higher preferences for extraverted, open and agreeable lecturers. There was some evidence of the student–lecturer personality match. Limitations and further research options were discussed.  相似文献   
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