Evaluation of ovulisa: An indigenous ELISA kit for detection of ovulation     

G. M. Sankolli  M. I. Khatkhatay  M. P. Desai  D. K. Pardhe  P. C. Ishrad  U. M. Joshi 《Indian journal of clinical biochemistry : IJCB》1992,7(1):71-74

Aprototype kit for the detection of occurrence of ovulation based on urinary pregnanediol glucuronide estimations by ELISA was developed in our laboratory. This kit was sent for evaluation at 4 centres in Bombay and Pune, India. The diagnosis of ovulation/anovulation based on the results of the kit is comparable with that based on reference parameters commonly used (ultrasonography of ovarian follicles and serum progesterone estimations). The accuracy of the test was 93.5%, specificity was 87.5% and sensitivity was 95.7%. This rapid indigenous test can be very useful in assessing ovulatory status of the woman by the clinicians in their offices.  相似文献   

“Hurt People,Hurt People”: The Trauma of Juvenile Incarceration     

Desai  Shiv R. 《The Urban Review》2019,51(4):638-658

The Urban Review - While approximately one in three youths are identified by juvenile probation officers as needing mental health services, researchers estimate that between 67 and 90% of detained...  相似文献   

A new industry creation and originality: Insight from the funding sources of university patents     

Marco Guerzoni  T. Taylor Aldridge  David B. Audretsch  Sameeksha Desai 《Research Policy》2014

Scientific breakthroughs coming from universities can contribute to the emergence of new industries, such as in the case of biotechnology. Obviously, not all research conducted in universities leads to a radical change from existing technological trajectories. Patents and patent dynamics have long been recognized as critical in understanding the emergence of new technologies and industries. Specifically, patent citations provide insight into the originality of a discovery that has received patent protection. Yet while a large body of literature addresses the impact of patent originality on various firm performance measures, we address the question of what conditions drive patent originality in the process of knowledge creation within the university. Using data on patented cancer research, we examine how research context – as reflected by the funding source for each scientist – is associated with patent originality. We find that when university scientists are partly funded by their own university, they have a higher propensity to generate more original patents. By contrast, university scientists funded either by industry or other non-university organizations have a lower propensity to generate more original patents. The significance of our findings in the cancer research setting call for further research on this question in other research fields.  相似文献   

Feasibility of determination of fertile period in Indian women based on urinary hormone estimations     

Meena Desai  U. M. Donde  M. Ikram Khatkhatay 《Indian journal of clinical biochemistry : IJCB》2001,16(1):127-131

Baseline data available on the excretory profiles of estrone giucuronide (E₁G), pregnanediol glucuronide (PdG) and luteinising hormone (LH) on human menstrual cycles (n=104) was retrospectively analysed for identifying the limits of fertile period (FP) to be used as natural method of family planning. The limits of fertile period are suggested based on centile distribution of E₁G and PdG levels during defined phase of menstrual cycle. Two approaches, which do not involve any mathematical calculation are suggested. In approach A, fertile period is said to have started when E₁G value of 35 ng/ml is reached and is said to have ended when the PdG value of 2 μg/ml on two consecutive days is obtained. The criteria were applied to 30 test cycles in whom authentic fertile period was identified based on excretory profiles of E₁G, PdG and LH throughout the menstrual cycles. When approach A was followed the authentic fertile period was covered in 27 cycles giving an accuracy of 90% with a mean fertile period length of 9.11+1.9 days. In approach B, the cut off limit of E₁G value was increased to 55 ng/ml in order to reduce the days of abstinence. Though the length of the fertile period was reduced to 7.2+1.5 days the accuracy of the approach was 66.6%. Thus the approach A which has accuracy of 90% may appeal to determined couples who wish to practice family planning by periodic abstinence or restrict the use of barrier methods.  相似文献   

Mentoring partnerships in a community technology centre: A constructionist approach for fostering equitable service learning     

Yasmin B. Kafai  Shiv Desai  Kylie A. Peppler  Grace M. Chiu  Jesse Moya 《Mentoring & Tutoring: Partnership in Learning》2013,21(2):191-205

Mentoring programmes have gained increasing popularity in institutions of higher education to support undergraduates in community service or outreach efforts. Many of these programmes partner mentors with inner‐city youth, providing assistance in underserved communities while mentors gain experiences that connect theory and practice. Here we report on two years of fieldwork in a Community Technology Centre that created mentoring partnerships in which 36 liberal arts undergraduates engaged with local youth to design, create, and build technology projects involving graphics, video, music, and animation. We analysed over 200 field notes, which described their mentoring interactions over eight weeks and conducted exit interviews about their mentoring experiences. Our results indicate that mentors participated not just as more knowledgeable peers but also as facilitators, advisors, observers and, most importantly, as learners in this process. In the interviews, nearly all mentors reviewed assumptions about their own learning and mentoring, in addition to reflections about social issues. We discuss the importance of these findings for conceptualising mentoring as a partnership by creating more equitable interactions in service learning initiatives. We also address the role of constructionist activities in facilitating learning opportunities for both mentors and mentees.  相似文献   

Multilingualism in South Africa with Particular Reference to the Role of African Languages in Education     

Zubeida Desai 《International Review of Education/Internationale Zeitschrift für Erziehungswissenschaft/Revue internationale l'éducation》2001,47(3-4):323-339

In this paper it is argued that language policy can play a central role in enabling citizens of a country to participate in the political, educational, social and economic life of that country. Or it can deny them that right. In discussions on the role of African languages, there is a tendency to confine the discussion to language in education. I argue that unless we locate the discussion in a broader context, we are not going to make much progress in extending the use of African languages beyond the home domain. The paper therefore consists of three sections. The first section looks broadly at the domains where language has an impact. The second section briefly outlines a process underway in South Africa to develop a framework for a national language policy, whilst the final section looks at the implications of this for education. Here I look at language in Education Policy in Practice. I give examples from a piece of primary research that I have conducted with Xhosa -speaking Grade 4 and Grade 7 learners who have been given pictures to describe first in Xhosa and then in English. The examples show the rich vocabulary children have when they express themselves in Xhosa and the poor vocabulary they have when they express themselves in English.  相似文献   

The design and development of the dragoon intelligent tutoring system for model construction: lessons learned     

Jon Wetzel  Kurt VanLehn  Dillan Butler  Pradeep Chaudhari  Avaneesh Desai  Jingxian Feng 《Interactive Learning Environments》2017,25(3):361-381

This paper describes Dragoon, a simple intelligent tutoring system which teaches the construction of models of dynamic systems. Modelling is one of seven practices dictated in two new sets of educational standards in the U.S.A., and Dragoon is one of the first systems for teaching model construction for dynamic systems. Dragoon can be classified as a step-based tutoring system that uses example-tracing, an explicit pedagogical policy and an open learner model. Dragoon can also be used for computer-supported collaborative learning, and provides tools for classroom orchestration. This paper describes the features, user interfaces, and architecture of Dragoon; compares and contrasts Dragoon with other intelligent tutoring systems; and presents a brief overview of formative and summative evaluations of Dragoon in both high school and college classes. Of four summative evaluations, three found that students who used Dragoon learned more about the target system than students who did equivalent work without Dragoon.  相似文献   

Principals' and teachers' attitudes and knowledge of inclusive education as predictors of effective teaching practices in Ghana     

Ahmed Bawa Kuyini  Ishwar Desai 《Journal of Research in Special Educational Needs》2007,7(2):104-113

Surveys and observations were undertaken in selected primary schools in Ghana to determine whether principals' and teachers' attitudes towards and knowledge of inclusive education, as well as principals' expectations of teachers in implementing inclusion, were predictors of effective teaching practices in their classrooms. The sample of 128 educators (20 principals and 108 teachers) drawn from 20 primary schools in two districts, were required to respond to questionnaire measures of Attitude Towards Inclusive Education Scale (ATIES), Knowledge of Inclusive Education Scale (KIES) and Principals' Expectations Scale (PES). Of the total number of teachers ( N  = 108), 37 were observed during instructional delivery in their classrooms. The data were analysed by a variety of statistical procedures including Regression Analysis and Discriminant Function Analysis. In the context of the Theory of Planned Behaviour (Ajzen, 1985), the results showed that whilst attitudes towards inclusion (attitude element) and knowledge of inclusion (perceived behavioural control element) predicted effective teaching practices, principals' expectations (subjective norm) did not. Implications for the implementation of effective inclusive practices in Ghanaian schools and the need for future research are discussed.  相似文献   

Evaluation of antioxidant properties of berries     

P. Rani  K. Meena Unni  J. Karthikeyan 《Indian journal of clinical biochemistry : IJCB》2004,19(2):103-110

The present paper focuses on assessing the levels of various enzymatic and non-enzymatic antioxidants in selected berries of Indian sub-continent viz., gooseberry, grapes, orange and tomato. This study has revealed that orange, tomato and grapes possess predominant quantities of enzymatic antioxidants namely SOD, catalase and glutathione peroxidase respectively. The levels of antioxidants analyzed namely reduced glutathione, vitamin C and vitamin A were maximal in grapes, orange and tomato respectively. All the extracts of berries included in the present study inhibited iron inducedin vitro lipid peroxidation in erythrocytes, the extend of inhibition being highest for gooseberry and orange compared to tomato and grapes which could be attributed to their in-built antioxidant system.  相似文献   

Role of Brain Biomarker in Predicting Clinical Outcome in Hypertensive Cerebrovascular Ischemic Stroke     

Anuradha Bharosay  Vivek Vikram Bharosay  Kiran Saxena  Meena Varma 《Indian journal of clinical biochemistry : IJCB》2018,33(2):178-183

This study was undertaken to evaluate the role of serum neuron specific enolase (NSE) in prediction of disability and neurological worsening in hypertensive ischemic cerebrovascular stroke. 80 hypertensive ischemic stroke patients diagnosed by a neurologist as per WHO definition along with radiological findings suggestive of cerebrovascular stroke and differentiating from hemorrhagic stroke and 60 controls having essential hypertension coming to hospital because of regular checkup or headache but with no neurological disease were included in the study. Neurological disability was assessed by NIHSS at the time of admission (within 72 h from the onset of stroke) and on 7th day after admission and cases were categorized into mild, moderate and severe disability. Venous blood samples were drawn within 72 h from the onset of symptoms. The samples were processed as per the laboratory protocol. The serum NSE samples were analyzed using an enzyme immunoassay based on the sandwich technique. We observed raised serum NSE in hypertensive ischemic stroke (17.4 ± 5.4 ng/ml) with significant association between different hypertensive groups than in hypertensive controls (9.1 ± 0.75 ng/ml). Greater degree of disability was observed in hypertensive stroke patients with raised serum NSE and hypertensive patients with mean serum NSE level of 22.9 ± 3.6 ng/ml and dyslipidemia had greater probability of neurological worsening as compared to those with mean serum NSE level of 12.7 ± 1.2 ng/ml. Serum NSE levels can serve as a peripheral indicator of neuronal damage and assist in the prediction of disability and clinical outcome in hypertensive cerebrovascular ischemic stroke patients.  相似文献