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Lucijanic M Petrovecki M 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(2):151-155
Analyzing events over time is often complicated by incomplete, or censored, observations. Special non-parametric statistical methods were developed to overcome difficulties in summarizing and comparing censored data. Life-table (actuarial) method and Kaplan-Meier method are described with an explanation of survival curves. For the didactic purpose authors prepared a workbook based on most widely used Kaplan-Meier method. It should help the reader understand how Kaplan-Meier method is conceptualized and how it can be used to obtain statistics and survival curves needed to completely describe a sample of patients. Log-rank test and hazard ratio are also discussed. 相似文献
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A longitudinal assessment of college student engagement in good practices in undergraduate education 总被引：1，自引：0，他引：1
The purpose of this study was to determinewhether student engagement in three goodeducational practices (cooperation with peers,active learning, faculty-student interaction)increased between 1983 and 1997 in response tothe calls to improve the quality ofundergraduate education in the United States.The data source was 73,050 students whocompleted the College Student ExperiencesQuestionnaire. The results from multipleregression and effect size analyses showed thatthe frequency of involvement in these goodpractices did not change over time. Variationin the scores of the three indicators acrossyears and types of institution(doctoral-granting universities, comprehensiveuniversities, liberal arts colleges) wasminimal indicating a stable pattern with onlyrandom fluctuations during this 15 yearperiod. 相似文献
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Ivana Mijatovic Mladen Cudanov Sandra Jednak Djordje M. Kadijevich 《Teaching in Higher Education》2013,18(5):506-517
In this paper, our aim is to explore the predictors of adoption by students of a Learning Management System (LMS) based on a Modular Object-Oriented Dynamic Learning Environment as well as the influence of active student participation and the interactive usage of an LMS on the achievements of students in a blended learning environment. Our study was conducted on 169 students, who are using an LMS for the first time in their studies, from the largest university from Serbia. Our findings indicate that students' active participation in class has a stronger positive effect on students' achievement than does students' interactive usage of the LMS. A stepwise linear regression analysis revealed that a student's interactive usage of the LMS and his/her active participation in class accounted for 47% of the variation in a student's achievement. A student's interactive usage of the LMS is only affected by his/her perceived easy usage of the LMS. 相似文献
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This research study addresses differences in student perception of the significance of Moodle learning management system (LMS) quality characteristics and differences in student satisfaction in regard to such characteristics. Therein, it has been proven in this study that male and female students are equally satisfied with Moodle LMS quality characteristics and that there is a difference in the significance that students give to these characteristics. When students were observed in regard to their age and year of study, it was found that these groups assigned different significance levels to quality characteristics and were not equally satisfied with them. It was also found that there is a substantial statistical difference in the significance students gave to quality characteristics and in student satisfaction itself, according to how much time they spent using the Moodle application, which is also noted as one of the most important aspects of the research conducted. A further analysis of the variables demonstrated that the following components of quality characteristics were more important to female students: average waiting time for a response, feedback quality, material thoroughness, material clarity, website user-friendliness, cooperation diversity, and material quantity. 相似文献
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Turkovic LF Pizent A Dodig S Pavlovic M Pasalic D 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(2):217-224
Introduction:
Metabolic syndrome (MetS) is a multifactorial disorder in which dyslipidemia plays an important role. Fatty acid-binding protein 2 (FABP 2) is responsible for transport of free fatty acids in the intestinal endothelium cells. FABP2-genetic variants might affect plasma lipid concentrations and intracellular lipid transport. The aim of this study was to investigate the association between FABP2 Ala54Thr genetic polymorphism and metabolic syndrome and some biochemical and anthropological parameters in elderly subjects.Materials and methods:
This cross-sectional study included 140 men and 176 women older than 70 years. Fasting serum concentration of glucose, lipid parameters, total proteins and C-reactive protein were determined by standardized methods. Presence (MetS(+)) or absence (MetS(−)) of MetS was determined according to criteria of the International Diabetes Federation. FABP2 genetic polymorphism Ala54Thr (rs1799883) was genotyped with PCR-RFPL.Results:
The genotype frequencies for Ala/Ala, Ala/Thr and Thr/Thr genotype were 60, 36 and 6 in MetS(−), and 131, 70 and 13 in MetS(+), respectively, without statistical significance (P = 0.567). Ala/Ala genotype was a subgroup of non-carriers, while Ala/Thr and Thr/Thr genotypes were Thr54-carriers. Median triglyceride concentration was significantly lower in carriers then in non-carriers for whole MetS(+) group (P = 0.050); there were no significant difference between men with MetS (P = 0.144), but there was a difference between women with MetS (P = 0.020). T-test showed that mean HDL cholesterol concentrations in MetS(+) group for Thr54-carriers was significantly higher in whole group (P = 0.001), and for both genders (men P = 0.039; women P = 0.004) as compared to non-carriers.Conclusions:
FABP2 genetic polymorphism is associated with lower triglyceride and higher HDL-cholesterol concentrations in elderly subjects with MetS. This genetic variation might be a useful marker for understanding dyslipidemia in MetS. 相似文献10.