Implementation of instructional innovations in K-8 science classes: perspectives of inservice teachers     

Pradeep Maxwell Dass 《International Journal of Science Education》2013,35(9):969-984

The Iowa Chautauqua Programme (ICP) was disseminated through the National Diffusion Network (NDN) of the US Department of Education as an exemplary model of professional development for inservice science teachers. As a result, several new professional development programmes, emulating the Iowa Chautauqua model, were initiated in diverse settings across the USA. Adhering closely to the principal features of the ICP, the Collier Chautauqua Programme (CCP) was developed in Collier County, Florida. Teacher concerns associated with classroom implementation of instructional innovations promoted by the programme were studied qualitatively during the first year of programme implementation. Data were collected through individual and focus group interviews, workshop and classroom observations, and pre-formatted teacher journals. These data were analysed using the stages of concern (SoC) of the concerns based adoption model (CBAM) as the conceptual framework. Results reveal intricate relationships between classroom implementation by teachers and programme implementation by the school district.  相似文献   

Antagonistic effect of FePP on the ethanol mediated induction of hepatic, renal and splenic δ-amino levulinic acid synthase activityin vivo in rats     

Ramesh Chandra  Ritu Aneja  Charu Rewal  Swati Bhowmik  Sujata K. Dass  Ritu Jain 《Indian journal of clinical biochemistry : IJCB》2000,15(2):141-147

In the current study, we report perturbations in hepatic, renal and splenic heme synthesis at the level of the rate limiting enzyme, δ-amino levulinic acid synthase (ALA-S) on ethanol administration independently and in conjunction with iron-protoporphyrin (FePP) in male Wistar rats. Excessive ethanol administration (5 ml/kg bw) resulted in a significant induction of hepatic, splenic and renal ALA-S activity. Simultaneous administration of FePP (50 μmol/kg bw) reverted the observed induction response to a sharp decline. The features of the action of ethanol and FePP togetherin vivo, i.e. a substantial inhibition of ALA-S is suggestive of the beneficial effects of this formulation in acute attacks of porphyria.  相似文献   

Conference agenda     

Nishant Shah 《Inter-Asia Cultural Studies》2013,14(3):349-352

ABSTRACT

The Indian state, when it announced the opening of its borders – physical and imaginary – to globalisation, also embraced new digital technologies of telecommunication and transportation in its attempt to reconfigure itself as a global player in the world market. The neo‐liberal economic policies and the restructuring of the State had immediate and far reaching impact on the question of citizenship. The technologised State posited the need for a technosocial subject – a subject that was not only a consumer/user of technology but also subject to the different technological networks instituted towards a new‐modernism. The fetishisation of such a technosocial subject entails a new regime of discipline and containment that produces certain glorified non‐legal subject positions which challenge the efforts of the State to create a homogeneous sanitised cyberscape. This paper is an attempt to examine the production of illegalities with reference to cyberspace, to make a symptomatic reading of new conditions within which citizenships are enacted, in the specific context of contemporary India. Looking at one incident each, of cyber‐pornography and cyber‐terrorism, the paper sets out to look at the State’s imagination of the digital domain, the positing of the ‘good’ cyber citizen, and the production of new relationships between the state and the subject. This essay explores the ambiguities, the dilemmas and the questions that arise when Citizens become Subjects, not only to the State but also to the technologies of the State.  相似文献   

Cadmium, carcinogen, co-carcinogen and anti carcinogen     

Ramesh Chandra  Sujata K. Dass  Priyanka Tomar  Manisha Tiwari 《Indian journal of clinical biochemistry : IJCB》2001,16(2):145-152

As a stress agent, inducing apoptosis and blocking it, Cd can have both helpful and harmful effects. The atmosphere is a thin envelope which makes the worid a global village. Cd is the most toxic metal in air. As both the first and second messenger of the stress response, it is synergistically toxic with all other stressors, including many other carcinogens. Elimination of Pb and its replacement with added benzene in gasoline appears to have increased the toxicity of atmospheric Cd. With scientific understanding of the molecular basis of Cd's role in carcinogenesis and anti-carcinogenesis, primary cancer prevention can be practiced by reducing Cd and chemical air pollution and educating the public on smoke cessation, healthy eating habits and stress reduction. Using the existing information on Cd and its effects, determinations could be made on established cancers so that individualized treatment protocols can be developed to improve patient care.  相似文献   

Inhibitory effect of metalloporphyrins in conjunction with cholesterol on hepatic phospholipase A2 activityin vivo in rats     

Ramesh Chandra  Manisha Tiwari  Ritu Aneja  Sujata K. Dass  Archana Sharma 《Indian journal of clinical biochemistry : IJCB》2000,15(2):148-154

We investigated the effect of cholesterol and the metalloporphyrins cobalt mesoporphyrin (CoMP) and chromium protoporphyrin (CrPP) on phospholipase A₂ (PLA₂) activity and the consequent hepatic mitochondrial stability as well as on lipid concentrations. Our studies revealed that on administration of cholesterol, CrPP, CoMP as well as simultaneous adminstration of cholesterol and CrPP, there was an inhibition of PLA₂ activity. These moieties may therefore, be agents for preventing destabilisation of the mitochondrial membrane and the consequent pathological conditions which may arise due to membrane lysis. Our results revealed that cholesterol administration increased phospholipid concentration, albeit by modest amounts. Although the independent administration of metalloporphyrins led only to minor elevations in phospholipid concentration, the simultaneous administration of cholesterol and CrPP generated a steep elevation in the concentration of total phospholipid. Since cholesterol inhibits PLA₂ activity it has the potential of being therapeutic agent for preventing the pathological conditions which may arise due to membrane lysis.  相似文献   

Asia in the edges: a narrative account of the Inter-Asia Cultural Studies Summer School in Bangalore     

Nishant Shah 《Inter-Asia Cultural Studies》2013,14(2):306-314

Abstract

The Inter-Asia Cultural Studies Summer School is a Biennial event that invites Masters and PhD students from around Asia to participate in conversations around developing and building an Inter-Asia Cultural Studies thought process. Hosted by the Inter-Asia Cultural Studies Society along with the Consortium of universities and research centres that constitute it, the Summer School is committed to bringing together a wide discourse that spans geography, disciplines, political affiliations and cultural practices for and from researchers who are interested in developing Inter-Asia as a mode of developing local, contextual and relevant knowledge practices. This is the narrative account of the experiments and ideas that shaped the second Summer School, “The Asian Edge” which was hosted in Bangalore, India, in 2012.  相似文献   

Venture capital investment strategies under financing constraints: Evidence from the 2008 financial crisis     

Annamaria Conti  Nishant Dass  Francesco Di Lorenzo  Stuart J.H. Graham 《Research Policy》2019,48(3):799-812

This paper employs the 2008 financial crisis as an empirical setting to examine how investment strategies of venture capitalists (VCs) vary in the presence of a liquidity supply shock, and what the performance implications of these strategies are for their portfolio startups. We show that while, on aggregate, funded startups receive no less financing during the financial crisis than in non-crisis times, VCs allocate relatively more resources to startups operating in the VCs’ core sectors. We show that this skew allocation follows from VCs choosing to double down on their core-sector investing, rather than by a changed mix of investors or startups during the financial crisis. These effects are strongest for early-stage startups, for which information problems are most severe. Furthermore, these results are driven by the investment strategies of more-experienced VCs. Building on these findings, we find superior ex post performance among crisis-funded portfolio startups operating in more-experienced VCs’ core sectors.  相似文献   

An opium alkaloid-papaverine ameliorates ethanol-induced hepatotoxicity: Diminution of oxidative stress     

Ramesh Chandra  Ritu Aneja  Charu Rewal  Rama Konduri  Sujaka K. Dass  Shefali Agarwal 《Indian journal of clinical biochemistry : IJCB》2000,15(2):155-160

In this communication, we show the modulatory potential of papaverine, an opium alkaloid and a well known vasodilator agent on the ethanol-induced hepatic oxidative stress in male Wistar rats. Ethanol treatment (50% v/v) enhanced lipid peroxidation significantly accompanied by a decline in the activities of glutathione peroxidase (G-Px), glutathione reductase (GR) and depletion in levels of hepatic glutathione (GSH). Ethanol administration increased hepatic glutathione-s-transferases (GST). Enhanced lipid peroxidation induced by ethanol was significantly reduced when papverine was coadministered (P<0.05). In addition, the depleted levels of glutathione and inhibited activities of G-Px and GR recovered significantly (P<0.05) levelling off to control values on co-exposure. Papaverine (200 mg/kg bw) effectively antagonised the ethanol-induced lipid peroxidation and impaired glutathione levels and glutathione dependent enzyme systems. Our results suggest that papaverine is an effective chemopreventive agent in the liver and may suppress the ethanol-induced hepatotoxicity.  相似文献