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1.
M. Maneesh Sanjiba Dutta Amit Chakrabarti D M Vasudevan 《Indian journal of clinical biochemistry : IJCB》2007,22(1):138-142
Infertility is well-established harmful effect in chronic alcoholism and so far, there is no effective treatment for this
condition. The study was conducted to determine the effects of alpha tocopherol on ethanol induced testicular injuries in
male albino rats of Wistar strain. Five groups (n=6) of animals were used. Group I served as control. Group II received daily
1.6g ethanol/kg body weight/day for 4 weeks orally. Group III received 1.6g ethanol+80mg alpha tocopherol/kg body weight/day
for four weeks orally. Group IV received 1.6g ethanol/kg body weight for/day 4 weeks and followed by 80mg alpha tocopherol/kg
body weight/day for four weeks orally. Group V received 1.6g ethanol/kg body weight/day orally for 4 weeks, followed by 4
weeks abstinence. Twently-four hours after the last treatment the rats were sacrificed using anesthetic ether. Testes were
removed and used for the estimation of extent of lipid peroxidation and tissue levels of antioxidants and steroidogenic enzymes.
Alpha tocopherol treatment increased the activities of testicularΔ
5, 3β-HSD. Moreover, the treatment was also associated with significant decrease in testicular oxidative stress. Ethanol-induced
oxidative stress and decreased steroidogenesis can be reversed by treatment with alpha tocopherol. 相似文献
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Debraj Chakrabarti 《Resonance》2011,16(8):754-769
In this popular expository article, we discuss some important ways in which complex analysis in more than one variable is
different from complex analysis in one variable. Analytic continuation in several variables is contrasted with that in one
variable, and the notion of psuedoconvexity is defined. Hartogs phenomenon and the Levi problem are also discussed in an informal
way. 相似文献
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Necessary and sufficient conditions for reducibility of certain classes of multivariable polynomials are considered. The special case when a polynomial in that class can be factored into a finite product of single variable polynomials is investigated. A set of necessary and sufficient conditions for decomposing a multivariable p.r.f. into a sum of single variable p.r.f.'s is given. Examples to illustrate applications of sum and product separabilities of functions are given. 相似文献
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M. Maneesh H. Jayalakshmi T A Singh Amit Chakrabarti 《Indian journal of clinical biochemistry : IJCB》2006,21(1):165-168
In view of association of diabetes mellitus and male infertility, present study was designed to investigate the functional
status of hypothalamic pituitary gonadal (HPG) axis in diabetic men. Thirty-five diabetic men (BMI 22.24±0.21) in the age
group 20–40 (30.6±4.7) years were selected. Twenty-five healthy men (BMI 23.85±0.25), in the same age group (29.5±4.8) served
as control. Blood samples were collected for hormonal and biochemical estimations. Diabetic men had significantly low serum
testosterone with low LH and FSH, hypercholesterolemia, hypertriglyceridemia, hypoalbuminemia and increased oxidative stress.
Low serum testosterone in diabetic men was accompanied by low LH and FSH; the inability of the pituitary gland to respond
appropriately to a decline in testosterone implying central effect of high serum glucose on the interaction between the nervous
and endocrine system. Nutritional deficiency, increased oxidative stress and increased aromatase activity due to excessive
body fat might have also contributed to low serum testosterone. 相似文献
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Pal R Chakrabarti K Chakraborty A Chowdhury A 《Journal of Zhejiang University. Science. B》2005,6(8):756-758
INTRODUCTION Pencycuron [1-(4-chlorobenzyl)-1-cyclopentyl- 3-phenylurea], a relatively new non-systemic protec-tive fungicide for controlling sheath blight (Rhizoc-tonia solani) of rice (Sylvanie and Cornis, 1989; Tomlin, 1997), is expected to be used widely in ag-ricultural production particularly in Asia. However, information on the dissipation pattern of pencycuron in rice plant is lacking. Little information on the en-vironmental fate of pencycuron has been published although there … 相似文献
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Maneesh Mailankot H. Jayalekshmi Amit Chakrabarti D. M. Vasudevan 《Indian journal of clinical biochemistry : IJCB》2009,24(1):94-97
To investigate reversibility of ethanol induced testicular injuries on treatment with L-ornithine-L-aspartate, male Wistar
rats were treated with ethanol (1.6g/kg b.wt/day) and L-ornithine- L-aspartate (200mg/kg b.wt/ day) for 4 weeks. L-ornithine-L-aspartate
effectively prevented the ethanol induced body and testes weight reduction; changes in testicular weight well correlated with
body weight. Drug exhibited an ability to counteract ethanol induced oxidative challenge as it effectively reduced testicular
TBARS and increased tissue ascorbic acid, GSH and activities of superoxide dismutase, catalase, GSH-Red and Se-GSH-Px. However
the drug didn’t show promising effect on inhibitory effect of ethanol on testicular D5, 3-beta and 17-beta HSD (hydroxy steroid
dehydrogenase). 相似文献
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