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The paraoxonase gene family in humans includes three members: PON1, PON2 and PON3. The products of those three genes are the following enzymes: paraoxonase 1 (PON1), paraoxonase 2 (PON2) and paraoxonase 3 (PON3). PON1 is mainly associated with a high density lipoprotein (HDL). A small amount of this enzyme is also bound to very low-density lipoprotein (VLDL) and postprandial chylomicrons. PON1 possess organophosphatase, arylesterase and lactonase activity and it hydrolyzes many different substrates. It is also known that PON1 may have antiatherogenic function. Compared to the PON1, PON2 and PON3 are much less studied and described. PON2 is ubiquitously expressed intracellular protein, while PON3 is bound to HDL, like PON1. The both enzymes possess antioxidant properties.  相似文献   
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The popularity of business process re-engineering (BPR) and its international diffusion from the United States make it important to understand the influence of cultural factors on this concept. The global economic prominence of the Chinese and their distinctive cultural characteristics prompted our study of Chinese business process re-engineering. This article addresses a large gap in the Chinese management literature and is intended to help those who are managing organizations or marketing information technology (IT) products and related services in Greater China. We systematically compare IT-enabled change in the American and Chinese business cultures. Informal planning and process modelling, highly interdependent social and organizational relationships with ingrained hierarchies, and the prevailing attitudes towards information management and organizational change will shape the preparation for IT-enabled process innovation efforts as well as the design and implementation of IT-enhanced business process models in Chinese organizations.  相似文献   
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为了帮助学校控制教学质量,荷兰国家教育测量研究院(Cito)为初等教育阶段开发出一套监测与评估系统。该系统包括一系列连续的国家范围内的标准化考试,对学生受教育过程中的成绩进行纵向评估。本文介绍了该系统的主要内容、教育及心理测量依据以及提供的部分成绩报告,并重点讨论了荷兰学校如何利用这些报告改进和提高教学水平。  相似文献   
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