Antioxidant effect ofPhyllanthus emblica fruits on healing of indomethacin induced gastric ulcer in rats     

Pakrashi  Anita  Pandit  Srikanta  Bandyopadhyay  Sandip K.  Pakrashi  Satyesh C. 《Indian journal of clinical biochemistry : IJCB》2003,18(1):15-21

Post-treatment of the indomethacin induced ulcerated rats at the optimal dose of 100 mg/kg body-wt. orally for 7 consecutive days with the lyophilized aqueous extract of the fruits ofPhyllanthus emblica L. syn.Emblica officinalis Gaertn. (Euphorbiaceae) exhibited highly significant (p<0.001) enhancement of secretion of catalase, reduced glutathione and decrease in malonyldialdehyde (MDA). Furthermore, the gross morphological observation and highly significant (p<0.001) decrease of ulcer index (81.43%) indicated healing effect of the extract on gastric ulcer.  相似文献