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Cultural Studies of Science Education - India has borrowed a colonial legacy of English language education from its British colonizers. Post-Independence, education policies pertaining to the...  相似文献   
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Circadian rhythm of serum glucose, pyruvate, lactate and lactate dehydrogenase (LDH) was studied in normal healthy young volunteers at the onset (I Group, 7 cases) and peak (II Group, 8 cases) of winters in India with highly varied temperature. There was a significant difference, in the circadian rhythm of glucose, pyruvate and lactate dehydrogenase (LDH) of the two groups. A clockwise shift was observed in acrophase except in serum lactate, which is related to the energy demand in association with time qualified changes in diurnal activity of the individuals and change in photoperiod.  相似文献   
3.
Nychthemeral rhythmicity of urinary copper (Cu) was studied in 40 clinically healthy volunteers and 35 renal stone formers. A marked diurnal rhythm was noticed in urinary Cu levels in healthy subjects with maximum excretion at 0000 to 0600 hr followed by a progressive fall during the rest of the period reaching minimum between 1200 to 1800 hr in males and 0600 to 1200 hr in female volunteers. Similarly, all stone patients exhibited a definite rhythm in urinary Cu with significant amplitude and acrophases at 2145 hr for males and 2141 hr for female stone formers. However, there was no difference in mean 24-hr Cu excretion in male and female stone formers, whereas a significant change was observed in case of healthy subjects. Urinary Cu was found to be significantly increased in renal stone formers in comparison to healthy controls of either sex attributing a significant role of this overlooked trace mineral in the crystallization and/or activation of either of the process of stone formation in the renal tubules.  相似文献   
4.
Open educational resources (OER) are digitised material freely available to the students and self learners. Many institutions had initiated in incorporating these OERs in their higher educational system, to improve the quality of teaching and learning. These resources promotes individualised study, collaborative learning. If they are coupled with Learning Objects of Learning Management System (LMS), they can lead to opportunities for further pedagogical innovation. It has become increasingly important for educational institutions to support these resources, in a planned and systematic manner. Adapt, assemble and conceptualise existing OERs to respond to diverse learning needs of students and support a variety of learning approaches for a given learning goal is a challenge. In this work, convergence of OERs with Learning Objects is done through metadata using classification techniques. Localisation of these high quality learning materials with the learning content of LMS, delivered as a single instructional unit may help in greater knowledge delivery and this can satisfy the learning needs of diverse student.  相似文献   
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Traditionally small intestinal biopsy has been considered a gold standard for the diagnosis of celiac disease (CD). But now data has shown that serological markers like anti-tissue-transglutaminase antibodies (tTGA) can be used to make the diagnosis with great sensitivity and specificity. The objective of the present study was to evaluate whether patients with high probability of CD and high titre of tTGA, have a high probability of intestinal damage and may not require biopsy for final diagnosis. All the cases with tTGA levels ≥15 IU/ml and who subsequently underwent biopsy from July 2010 to June 2013 were selected. Histopathological findings graded as per Marsh classification were correlated with serum tTGA levels. Grade 3 lesions were considered diagnostic for the disease. Out of total 731 patients 470 had serum tTGA levels >100 IU/ml and 261 patients had <100 IU/ml. Highest levels of tTGA (219.3 IU/ml) were seen in grade 3c which was >12 times the normal cutoff value. Mean serum tTGA in higher histological grade i.e. 3 (3a, 3b, 3c) was 186.7 IU/ml (>12 times the normal cut off value) as compared to grade 1 which was 108.9 IU/ml (>7 times the normal cut off value). Using a tTGA cutoff value of 70 IU/ml, sensitivity was found to be 83.9% while specificity was 56.10% with an overall accuracy of 77.7%. This study confirms that a small intestinal biopsy is not always necessary for the diagnosis of CD in symptomatic patients with high tTGA levels (>70 IU/ml).  相似文献   
6.
This paper presents a trajectory-based online control reconfiguration mechanism against unknown fault occurring in an electric circuit. First, we demonstrate the modeling of an electric circuit by taking the time-trajectory viewpoint, where no a priori input–output partition has been made. The uniqueness of this viewpoint lies in the fact that it deals only with variables that describe the system without any dedicated (external or internal -type) representation. Subsequently, we illustrate a novel real-time fault-tolerant control (FTC) strategy based on this trajectory standpoint, which does not require an explicit model-based fault diagnosis unit. Instead, the controller is reconfigured directly based on the trajectories generated by the system in real-time, and the given control specifications. In this way, we efficiently excrete the shortcomings that are often seen in model-based fault-tolerant systems. The proposed FTC method is effectively demonstrated on an RLC circuit.  相似文献   
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Plasma vitamin E levels were estimated in 75 patients each of carcinoma breast and benign breast diseases. Mean plasma vitamin E concentration was found to be significantly reduced in malignancy compared to the controls as well as the non malignant conditions. The decrease in plasma vitamin E in cancer patients was directly related with the TNM stage of cancer. The levels, however, did not vary significantly with respect to histopathology or after 8 days of surgery.  相似文献   
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Kantak C  Zhu Q  Beyer S  Bansal T  Trau D 《Biomicrofluidics》2012,6(2):22006-220069
Here, we utilize microfluidic droplet technology to generate photopolymerizeable polyethylene glycol (PEG) hydrogel microbeads incorporating a fluorescence-based glucose bioassay. A microfluidic T-junction and multiphase flow of fluorescein isothiocyanate dextran, tetramethyl rhodamine isothiocyanate concanavalin A, and PEG in water were used to generate microdroplets in a continuous stream of hexadecane. The microdroplets were photopolymerized mid-stream with ultraviolet light exposure to form PEG microbeads and were collected at the outlet for further analysis. Devices were prototyped in PDMS and generated highly monodisperse 72?±?2 μm sized microbeads (measured after transfer into aqueous phase) at a continuous flow rate between 0.04 ml/h-0.06 ml/h. Scanning electron microscopy analysis was conducted to analyze and confirm microbead integrity and surface morphology. Glucose sensing was carried out using a F?rster resonance energy transfer (FRET) based assay. A proportional fluorescence intensity increase was measured within a 1-10 mM glucose concentration range. Microfluidically synthesized microbeads encapsulating sensing biomolecules offer a quick and low cost method to generate monodisperse biosensors for a variety of applications including cell cultures systems, tissue engineering, etc.  相似文献   
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