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1.
A novel microfluidic device which consists of two stages for particle focusing and separation using a viscoelastic fluid has been developed. A circular capillary tube was used for three-dimensional particle pre-alignment before the separation process, which was inserted in a polydimethylsiloxane microchannel. Particles with diameters of 5 and 10 μm were focused at the centerline in the capillary tube, and the location of particles was initialized at the first bifurcation. Then, 5 and 10 μm particles were successfully separated in the expansion region based on size-dependent lateral migration, with ∼99% separation efficiency. The proposed device was further applied to separation of MCF-7 cells from leukocytes. Based on the cell size distribution, an approximate size cutoff for separation was determined to be 16 μm. At 200 μl/min, 94% of MCF-7 cells were separated with the purity of ∼97%. According to the trypan blue exclusion assay, high viability (∼90%) could be achieved for the separated MCF-7 cells. The use of a commercially available capillary tube enables the device to be highly versatile in dealing with particles in a wide size range by using capillary tubes with different inner diameters.  相似文献   
2.
This paper examines the complex relation between interest and comprehension recorded by postgraduate students in a language teacher education programme at various stages of two-hour lectures. The quantitative analysis suggests that its relationship with comprehension changes as the lecture continues. The analysis is also triangulated with the qualitative responses reported by students at different stages of the lecture. The type of comprehension that co-occurs with increasing interest differs from the type of comprehension that co-occurs with maintaining interest. Although the effect of comprehension on interest is low at the beginning of the lecture, its effect is more frequently noted as important at the later stages of the lecture. Postdictability (i.e., the ability to determine after the fact that unpredictability and difficulty that have been raised in the earlier parts of the lecture hang together and make sense) seems important in increasing interest, especially at the later stages of the lecture.  相似文献   
3.
Constructivist instruction has been implemented in the current instructional innovation in Singapore. Large scale survey study was conducted to examine the roles of teacher efficacy in implementing the innovative constructivist instruction. The results showed that the positive correlation between teacher efficacy and constructivist instruction was stronger than the correlation between teacher efficacy and didactic instruction. The study suggests that policy makers and school leaders should try to improve teacher’s efficacy beliefs so that innovative instruction could be effectively implemented by school teachers.  相似文献   
4.
罗辅林  吴银松 《编辑学报》2004,16(2):144-145
质量是期刊永恒的主题.期刊质量直接影响到期刊的发行量,发行量又制约着发布广告的数量,广告数量对期刊质量又有影响,三者互为因果关系.正确处理好三者的关系,就能为期刊社创造良好的社会效益和经济效益,使期刊走上自我发展的良性循环道路.  相似文献   
5.
The motivation for this research was to understand under what conditions supply chain cooperation might be feasible and under what circumstances it is not. Whereas previous research focuses on dyads in a supply chain, our research seeks to examine a possible factor that can explain why truly cooperative supply chains involving more than two firms are a rarity among independent firms. This research extends the use of game theory to demonstrate the potential impact of a multiple‐tier supply chain agreement.  相似文献   
6.
WISC and WISC-R IQs of two groups of normal ten-year-old children from divergent socioeconomic backgrounds (N = 36) were compared in a counterbalanced research design. Generally, all WISC mean IQs were higher than the WISC-R mean IQs for both groups of children. Significantly higher WISC IQs were obtained on the Verbal and Full Scales of the low socioeconomic group and on the Performance and Full Scales of the high socioeconomic group. Correlations between tests for Verbal, Performance, and Full Scale IQs were.95,.79, and.91 for the low socioeconomic group, and.84,.57, and.87 for the high socioeconomic group. Although practice effects did not appear to significantly affect IQs of the low socioeconomic group, various practice effects were observed in the high socioeconomic group. Negative effects were observed for both WISC and WISC-R on the Verbal Scale, whereas positive effects were observed on both Performance and Full Scales in this group. Analysis of simple effects reveals that WISC and WISC-R IQs did not differ significantly upon first administration, but were significantly different upon second administration. Conclusions were drawn that while WISC-R yields a lower IQ estimate than WISC for children of lower ability, results were not so clear for the children of higher ability, due to practice effects which disproportionately favor increases on WISC IQs upon second administration. The greater practice effects found on the WISC have implications for comparisons of the two tests in counterbalanced research designs. Simple randomized or treatment-by-levels design may be more useful in comparisons of the WISC and the WISC-R because of the bias introduced by counterbalanced designs.  相似文献   
7.
8.
This article presents an alternative approach to using service-learning courses to help students develop cultural competence. Service learning often comes from a deficit model that views the providers of a service as advantaged and the recipients as disadvantaged. The Conceptual Model for Cultural Engagement (CMCE) recognizes that those many deem as the disadvantaged have assets to share. The CMCE develops long-term, asset-based, reciprocal relationships between faculty members, community partners, and higher education students. During this relationship, all of the individuals actively participate in culturally engaged learning. The goal is to develop culturally effective members of our society who are educated to interact effectively with individuals from diverse backgrounds.  相似文献   
9.
ABSTRACT

This paper examines the multiple, intersecting identities expressed by international taught-post graduate students who are studying in a culture and language that is not their own. The study presented includes the collection of data around and beyond a planned pedagogical intervention on a pre-sessional EAP programme. The data were thematically analysed. Conflicting and intersecting identities emerged around themes of: performative, representational and core identities; international, national and individual identity; troublesome and transformative knowledge; power, agency and choice. These interwove with key underlying pre-occupations: language development; disciplinary knowledge and societal structures. By focussing on identity studies alongside the language and culture of academic contexts, international students developed an understanding of, and reflexivity around, their position within UK HE contexts. I argue this focus eased transition into a new study environment and allowed students to both better access the taught and hidden curriculum, and to understand their resistance to it.  相似文献   
10.
To test the efficacy of temporally patterned kinesthetic and auditory stimulation for promoting development of infants born prior to term, 88 preterm infants, below 35 weeks gestation, were assigned to 1 of 4 experimental or control groups. Control subjects received regular hospital care; fixed interval subjects received 15 min of rocking/heartbeat stimulation each hour; self-activating subjects received 15 min rocking/heartbeat when inactive for 90 sec, but only for 1 stimulation period per hour. Assessments included measures of neurological functioning, sleep-wake activity, mother-infant interaction, and mental and motor development at 8 and 24 months. All experimental infants, compared to controls, showed decreased rates of activity while in the hospital, fewer abnormal reflexes, and better orienting responses. At 24 months, experimental infants scored significantly higher on the Mental Development Index of the Bayley Scales. Few differences were found in parent-infant interaction patterns. The results indicate that both temporal patterning and contingent responsiveness in the preterm infant's early environment contribute positively to some aspects of the development of such infants.  相似文献   
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