基于二模复杂网络的隐性知识发现方法研究——以潜在药物靶点挖掘为例     

李东巧  陈芳  韩涛  杨艳萍  王学昭  王燕鹏  Cynthia Liu  Yingzhu Li 《图书情报工作》2020,64(21):120-129

[目的/意义] 通过构建二模复杂网络模型，揭示隐藏在海量文献中的隐性知识。[方法/过程] 通过NetworkX复杂网络工具包，依据任意两个节点的共现关系构建二模复杂网络模型；对网络模型中节点的共现关系进行加权，计算网络的拓扑信息并进行AP聚类，提取节点间的直接关系；采用AUC方法对AA、JC、加权改进的wAA和wJC等4种链路预测算法进行评价，遴选出最合适的预测算法，并对复杂网络的隐性关系进行预测分析。[结果/结论] 以潜在药物靶点挖掘为例进行的实证研究结果表明，wAA链路预测算法为最优的链路预测算法；二模复杂网络模型、指标和方法体系在美国化学文摘社数据库中的药物靶点挖掘中具有一定的有效性。下一步计划在其他数据库中或其他研究领域中进行尝试，以进一步验证该模型的通用性和有效性。  相似文献   

A Corpus-Based Learning Method of Compound Noun Indexing Rules for Korean     

Jee-Hyub Kim  Byung-Kwan Kwak  Seungwoo Lee  Geunbae Lee  Jong-Hyeok Lee 《Information Retrieval》2001,4(2):115-132

In Korean information retrieval, compound nouns play an important role in improving precision in search experiments. There are two major approaches to compound noun indexing in Korean: statistical and linguistic. Each method, however, has its own shortcomings, such as limitations when indexing diverse types of compound nouns, over-generation of compound nouns, and data sparseness in training. In this paper, we propose a corpus-based learning method, which can index diverse types of compound nouns using rules automatically extracted from a large corpus. The automatic learning method is more portable and requires less human effort, although it exhibits a performance level similar to the manual-linguistic approach. We also present a new filtering method to solve the problems of compound noun over-generation and data sparseness.  相似文献   

Editorial     

Professor Lee Harvey  Dr Celia Whitchurch 《Higher Education Quarterly》2009,63(3):217-218

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Effects of Manipulative Instruction on Solving Area and Perimeter Problems by Students with Learning Disabilities     

Mike Cass  Dennis Cates  Michelle Smith  Cynthia Jackson 《Learning disabilities research & practice》2003,18(2):112-120

Abstract. A multiple baseline design was employed to test the effect of manipulative instruction on the perimeter and area problem‐solving performance of middle and high school students who had been diagnosed with LD in the area of mathematics. Modeling, prompting/guided practice, and independent practice in conjunction with manipulative training were employed to teach both perimeter and area problem‐solving skills. Analysis of data revealed that the students rapidly acquired the problem‐solving‐skills, maintained these skills over a two‐month period, and transferred these skills to a paper and pencil problem‐solving format. This research extends previous findings by revealing that use of concrete manipulatives promotes the long‐term maintenance of skills.  相似文献   

Good High Schools for Students with Disabilities     

Catherine Cobb Morocco  Cynthia Mata Aguilar  Karen Clay  Nancy Brigham  Naomi Zigmond 《Learning disabilities research & practice》2006,21(3):135-145

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The Democratization of Mass Political Orientations in South Korea: Ascertaining the Cultural Dimension of Democratic Consolidation     

Shin  Doh Chull; Park  Chong-Min; Hwang  Ah-Ran; Lee  Hyeon-Woo; Jang  Jiho 《Int. Journal of Public Opinion Research》2003,15(3):265-284

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Non-finite loss and challenges to communication between parents and professionals     

Elizabeth Bruce  & Cynthia Schultz 《British Journal of Special Education》2002,29(1):9-13

Elizabeth Bruce PhD, a psychologist in private practice, and Cynthia Schultz PhD, honorary associate at LaTrobe University, both live and work in Australia. Their work on supporting parents who have children with special needs, however, has been published around the world. In this article Bruce and Schultz explore the notion of 'non-finite loss', defined as the ongoing sense of grief experienced by parents caring for children with severe disabilities. The authors discuss the issues that professionals need to consider when working with parents in these circumstances. The article closes with a set of recommendations for promoting more effective partnerships between parents and professionals.  相似文献   

Regulating IVF: a reply to concerns     

Lee S 《New scientist (1971)》1991,131(1783):8

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So many filters, so little time: the development of a search filter appraisal checklist          下载免费PDF全文

Julie Glanville  Sue Bayliss  Andrew Booth  Yenal Dundar  Hasina Fernandes  Nigel David Fleeman  Louise Foster  Cynthia Fraser  Anne Fry-Smith  Su Golder  Carol Lefebvre  Caroline Miller  Suzy Paisley  Liz Payne  Alison Price    Karen Welch 《Medical Library and Historical Journal》2008,96(4):356-361

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Manufacture and Date of a Goryeo dynasty Sutra Box with Mother-of-pearl Inlaid Decoration at the Rijksmuseum,Amsterdam     

Nanhee Lee 《文物保护研究》2018,63(3):163-170

Currently, about ten Goryeo dynasty (918–1392 CE) sutra boxes are preserved in museums in Korea, Japan, the United States, the Netherlands, and the United Kingdom. This article is the result of an examination of a sutra box in the collection of the Rijksmuseum, Amsterdam (hereafter ‘Rijksmuseum sutra box’), which was first introduced to a European audience in the Transactions and Proceedings of the Japanese Society, in 1913–1914. The Rijksmuseum sutra box differs from other Goryeo sutra boxes. With its altered structure and modified motifs, this box bears significant value, not only for the research of thirteenth-century Goryeo mother-of-pearl art, but also for the study of cross-cultural adaptations in East Asian lacquer art. This article investigates the date of manufacture of the sutra box by analysing the manufacturing techniques and its various original and modified parts. For this, an X-ray radiograph was carried out for the first time. As a result, discoveries have been made regarding the structure and decoration of the lower part, which has been modified and is different from Goryeo mother-of-pearl sutra boxes. Finally, this paper reconsiders conservation and repair of Goryeo sutra boxes, as illuminated by an understanding of the original and repaired parts of this box.  相似文献