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1.
The study was carried out with 175 Turkish students by using drawings at different ages understanding of gene, DNA and chromosome concepts. Students from 8th, 9th, 11th grades and, science and biology student teachers were simply asked to draw the structure of gene, DNA and chromosome in a cell and also to give explanations about these three concepts. Differences in understanding between the age groups were found to be significant for the concepts of gene and DNA. None of the groups exhibit sound understanding and regardless of the age levels, students in all groups had alternative ideas about the three concepts investigated.  相似文献   
2.

Introduction

Total 25-hydroxyvitamin D [25(OH)D] is the most reliable indicator of vitamin D status. In this study, we compared two automated immunoassay methods, the Abbott Architect 25-OH Vitamin D assay and the Roche Cobas Vitamin D total assay, with the liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Materials and methods

One hundred venous blood samples were randomly selected from routine vitamin D tests. Two of the serum aliquots were analyzed at the Abbott Architect i2000 and the Roche Cobas 6000’s module e601 in our laboratory within the same day. The other serum aliquots were analyzed at the LC-MS/MS in different laboratory. Passing-Bablok regression analysis and Bland-Altman plot were used to compare methods. Inter-rater agreement was analyzed using kappa (κ) analysis.

Results

The Roche assay showed acceptable agreement with the LC-MS/MS based on Passing-Bablok analysis (intercept: -5.23 nmol/L, 95% CI: -8.73 to 0.19; slope: 0.97, 95% CI: 0.77 to 1.15). The Abbott assay showed proportional (slope: 0.77, 95% CI: 0.67 to 0.85) and constant differences (intercept: 17.08 nmol/L; 95% CI: 12.98 to 21.39). A mean bias of 15.1% was observed for the Abbott and a mean bias of -14.1% was observed for the Roche based on the Bland-Altman plots. We found strong to nearly perfect agreement in vitamin D status between the immunoassays and LC-MS/MS. (κ: 0.83 for Abbott, κ: 0.93 for Roche) using kappa analysis.

Conclusion

Both immunoassays demonstrated acceptable performance, but the Roche Cobas assay demonstrated better performance than the Abbott Architect in the studied samples.Key words: 25-Hydroxyvitamin D, chromatography, immunoassay, methods, tandem mass spectrometry  相似文献   
3.
Objective: This prospective randomized clinical trial was conducted to evaluate the necessity of drainage after total thyroidectomy or lobectomy for benign thyroidal disorders. Methods: A total of 116 patients who underwent total thyroidectomy or lobectomy for benign thyroidal disorders were randomly allocated to be drained or not. Operative and postoperative outcomes including operating time, postoperative pain assessed by visual analogue scale (VAS), total amount of intramuscular analgesic administration, hospital stay, complications, necessity for re-operation and satisfaction of patients were all assessed. Results: The mean operating time was similar between two groups (the drained and non-drained groups). The mean VAS score was found to be significantly low in the non-drained group patients in postoperative day (POD) 0 and POD 1. The mean amount of intramuscular analgesic requirement was significantly less in the non-drained group. One case of hematoma, two cases of seroma and three cases of transient hypoparathyroidism occurred in the non-drained group, whereas one case of hematoma, two cases of seroma, two cases of wound infections and two cases of transient hypoparathyroidism occurred in the drained group. No patient needed re-operation for any complication. The mean hospital stay was significantly shorter and the satisfaction of patients was superior in the non-drained group. Conclusion: These findings suggest that postoperative complications cannot be prevented by using drains after total thyroidectomy or lobectomy for benign thyroid disorders. Furthermore, the use of drains may increase postoperative pain and the analgesic requirement, and prolong the hospital stay. In the light of these findings, the routine use of drains might not be necessary after thyroid surgery for benign disorders.  相似文献   
4.
Environmental attitudes depend on the relative importance that individuals attach to themselves, other people, or all living things. These distinct bases have been found to predict environmental concern, and may act as statistically significant determinants of pro-environmental behaviours. We claim that examining the complex nature of value orientations and concern levels among elementary school students as well as the interrelationships between these attributes could guide researchers and educators in Turkey. This study aimed (1) to explore Turkish elementary students’ ecocentric and anthropocentric attitudes, and environmental apathy; (2) to investigate their egoistic, altruistic and biospheric value orientations as well as their environmental concerns; (3) to examine relationships among environment-related attributes and (4) to determine the role of gender on these attributes. Participants seemed to be highly concerned and held favourable ecocentric attitudes. Furthermore, students with higher levels of anthropocentric attitudes tended to exhibit higher levels of environmental apathy, and those expressing biospheric concerns held lower levels of egoistic concerns. The findings suggest that girls were significantly more concerned about environmental problems and tended to value nature more for its own sake than boys.  相似文献   
5.
This study was made in order to determine whether concepts are related to each other in the conceptual development of 6 year olds. The sample group of the study consisted of 40 children, 24 of which were girls and 16 were boys. The conceptual development of children was evaluated using the Bracken Basic Concept Scale (BBCS). Data were collected in a period of 8 weeks at two kindergartens, one belonging to the state and the other to the private sector. The data obtained were evaluated via the test of the significance of the difference between two matching elements. Cette étude a été exécutée pour déterminer si les concepts avaient été en rapport avec l'un l'autre dans le cours du développement conceptual des enfants au groupe de l'âge de 6 années. Le groupe des sujets a contenu de 40 enfants totaux, inclure 24 filles et 16 garçons. Les développements conceptuels des enfants ont été évalués sur le Bracken Basic Concept Scale (BBCS). Les données se sont rassemblés sur un travail qui dure pour 8 semaines dans deux jardins d'enfants institutionnels, un privé et un public. Les données rassemblés ont été évalués sur la base du test sur importance de la différence entre deux égaux. Este Estudio fue realizado para determinar si los conceptos se relacionaran a nosotros en el curso del desarollo conceptual de los niños al grupo de edad de 6 años. El grupo de ejemplos constó de de total 40 niños, incluyendo a 24 muchachas y 16 muchachos. Se evaluaron los desarollos conceptuales de los niños en el Bracken Basic Concepts Scale (BBCS). Los datos se coleccionaron en un trabajo que dure durante 8 semanas en dos jardines de infantes institucionales, uno privado y uno público. Los datos reunido se evaluaron en base a la prueba en la importancia de la diferencia entre dos partidas.  相似文献   
6.
Research in Science Education - Informal science educators’ (ISEs) work with young children has received limited attention in the literature. We investigated ISEs’ goals for...  相似文献   
7.
This paper presents the development and initial validation of a feedback scale which measures the thoughts and affective reactions of prospective teachers concerning feedback on their teaching experiences. To reach this goal, data from 512 prospective teachers were used to test the internal consistency, exploratory and confirmative factor structure. While exploratory factor analysis was conducted on a random split-half sample of the data to examine the factor structure of the feedback scale items, confirmative factor analysis was conducted in the holdout sample. As a result of these analyses, it has been determined that the scale showed good validity and it has a structure composed of two factors; professional development and anxiety. Also, the reliability of these sub-factors of scale scores was found to be highly reliable. Overall, results suggest that this scale is a valid measurement that should reveal the viewpoints of prospective teachers regarding feedback in the form of observable behaviours for future research.  相似文献   
8.
This study examined the influence of socioeconomic (age, education, marital status, income, and health) and demographic variables and the quantity and quality of relationships with adult children, grandchildren, siblings and friends on life satisfaction of the elderly. Participants were 200 persons older than 60 years of age. Hierarchical regression analysis was used for data analysis. The three sets of regression models were run for each gender. Regression equations involved three sets of independent variables: socioeconomic, demographic, and relational (i.e., frequency, satisfaction) variables. When the three models were examined together, health and education made the highest contribution to females' life satisfaction. Health had a similar effect on the life satisfaction of males.  相似文献   
9.
Psoriasis patients are determined to have a high ratio of coronary artery calcification. Fetuin-A and osteoprotegerin are systemic calcification inhibitors and related to vascular calcification and cardiovascular mortality. In this study we investigated the relationship between fetuin-A and osteoprotegerin levels in psoriasis patients. The study included 40 healthy volunteers and 40 psoriasis patients. Venous blood were collected from healthy volunteers and psoriasis patients in order to search the fetuin-A and osteoprotegerin levels. Disease severity were grouped as mild, moderate and severe according to psoriasis area and severity index (PASI). The relationship between fetuin-A and osteoprotegerin levels and clinical features as sex, PASI and presence of psoriatic arthritis were analyzed. Fetuin-A levels in psoriasis patients were statistically lower than the control group (p < 0.001). In serum osteoprotegerin levels, no statistically significant difference was found in two groups (p > 0.05). Serum fetuin-A and osteoprotegerin level differences were not statistically significant between patients with psoriatic arthritis history and those without. When we grouped patients in respect of their sexes fetuin-A and osteoprotegerin levels of males and females were not significantly different (p > 0.05). No correlation was detected between the ages and PASI scores and the fetuin-A and osteoprotegerin levels of patients. As a result fetuin-A levels in psoriasis patients are found to be low but not related to disease severity. In the light of our results we concluded that fetuin-A may have a role in psoriasis pathogenesis and may contribute to the calcification process developed in psoriasis.  相似文献   
10.
Coaches have identified the batter's weight shift as a critical component for promoting proper timing and balance in a baseball swing. Analysing the weight shift through maximum horizontal (Fx) and vertical (Fz) ground reaction forces (GRFs) of professional batters (N = 29; height = 185 +/- 6 cm; mass = 92 +/- 9 kg), the purpose of this study was to compare GRFs among swings against fastballs and changeups. General linear models were used to compare three conditions of interest: successful results against fastballs, successful results against changeups, and unsuccessful results against changeups. Batters had a similar loading mechanism and initial weight transfer from back foot to front foot regardless of pitch type, but peak front foot GRFx and GRFz occurred with significantly different magnitudes and at significantly different times, depending on the pitch type and hit result. Peak front foot GRFs were greater for successful swings against fastballs compared to both successful and unsuccessful swings against changeups. Peak front foot GRFs of unsuccessful swings against changeups occurred, on average, 15-20 ms earlier than successful swings against changeups and 30-35 ms earlier than successful swings against fastballs, quantifying how a changeup can disrupt the coordination of a hitter's weight shift.  相似文献   
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