排序方式： 共有15条查询结果，搜索用时 31 毫秒
1.
Ferenc Torma Zoltan Gombos Marcell Fridvalszki Gergely Langmar Zsofia Tarcza Bela Merkely Hisashi Naito Noriko Ichinoseki-Sekine Masaki Takeda Zsolt Murlasits Peter Osvath Zsolt Radak 《运动与健康科学(英文)》2021,10(4):470
BackgroudBlood flow restriction (BFR) with low-intensity resistance training has been shown to result in hypertrophy of skeletal muscle. In this study, we tested the hypothesis that BFR during the rest periods between acute, high-intensity resistance exercise sessions (70% of 1 repetition maximum, 7 sets with 10 repetitions) enhances the effects of the resistance training.MethodsA total of 7 healthy young men performed squats, and between sets BFR was carried out on one leg while the other leg served as a control. Because BFR was applied during rest periods, even severe occlusion pressure (approximately 230 mmHg), which almost completely blocked blood flow, was well-tolerated by the participants. Five muscle-specific microRNAs were measured from the biopsy samples, which were taken 2 h after the acute training.ResultsDoppler data showed that the pattern of blood flow recovery changed significantly between the first and last BFR. microRNA-206 levels significantly decreased in the BFR leg compared to the control. The mRNA levels of RAC-β serine/threonine-protein kinase v22, nuclear respiratory factor 1, vascular endothelial growth factor, lupus Ku autoantigen protein p70 genes (p < 0.05), and paired box 7 (p < 0.01) increased in the BFR leg. The protein levels of paired box 7, nuclear respiratory factor 1, and peroxisome proliferator-activated receptor γ coactivator 1α did not differ between the BFR leg and the control leg.ConclusionBFR, during the rest periods of high-load resistance training, could lead to mRNA elevation of those proteins that regulate angiogenesis, mitochondrial biogenesis, and muscle hypertrophy and repair. However, BFR also can cause DNA damage, judging from the increase in mRNA levels of lupus Ku autoantigen protein p70. 相似文献
2.
In a social system or production line,the restrictions of the cost and the due-time exist in each period.Generally,whether these restrictions are satisfied is dependent not only on the risks of this period,but also on the risks generated beforehand.We consider controlling the production process by switching the processing rate to a faster one at a given period.This paper deals with the optimal switching period to minimize the total expected cost of the production process.We first propose the optimal switching period model,and then the mathematic formulation of the total expectation is presented.Finally,the policy of optimal switching period is investigated in detail by numerical experiments. 相似文献
3.
Hitoshi Inoue Eisuku Naito Mika Koshizuka 《International Information and Library Review》1997,29(3-4)
The author re-examines the concepts in the light of “digital literacy” to determine the problems, tasks and fields of common interest. He reviews the government actions in Japan in providing access to digital knowledge and in creating information literacy, such as schools, higher education, life-long education, etc. He explores which findings in recent developments in Japan can be of common interest and shared with other advanced, as well as developing countries. Finally, possibilities for future international co-operation are discussed. 相似文献
4.
Hitoshi Inoue Eisuku Naito Mika Koshizuka 《International Information and Library Review》2013,45(3-4):403-413
The author re-examines the concepts in the light of “digital literacy” to determine the problems, tasks and fields of common interest. He reviews the government actions in Japan in providing access to digital knowledge and in creating information literacy, such as schools, higher education, life-long education, etc. He explores which findings in recent developments in Japan can be of common interest and shared with other advanced, as well as developing countries. Finally, possibilities for future international co-operation are discussed. 相似文献
5.
Journal of Science Teacher Education - 相似文献
6.
7.
Studies on bullying at school proliferate, but the discourse is seriously lacking in sociological perspective. The explanation as to why some students bully others has been sought primarily within the personal attributes of the bully and the victim. Despite the fact that the school is the place where most bullying occurs, school factors that are correlated with the prevalence of bullying have been under-investigated. In Japan, however, schools have been subject to great scrutiny. By reviewing the Japanese literature on bullying ( ijime ), this paper discusses factors that appear to contribute to the school climate in which bullying among students becomes commonplace. These include authoritarian, hierarchical, and power-dominant human relationships, alienating modes of learning, high levels of regimentation, dehumanising methods of discipline, and highly interventionist human relationships in an excessively group-oriented social environment. The paper suggests the paradigm of student bullying needs to be re-thought. 相似文献
8.
Tomiko Yakura Naoyuki Hatayama Chikako Kawahara Yusuke Ohmichi Mika Ohmichi Nobutaro Ban Shuichi Hirai Takashi Nakano Munekazu Naito 《Anatomical sciences education》2022,15(2):392-402
Although the methods for medical education continue to evolve due to the development of medicines, the cadaver dissection course still plays a fundamental role. The cadaver dissection course allows students to learn to handle instruments correctly while actively exploring three-dimensional anatomy. However, dissection comes with the risk of accidental injury. In recent years, the number of classes offered for the cadaver dissection course has decreased while the amount of knowledge required in clinical medicine has increased. Simulation-based education (SBE) has been proven to be an effective educational method that enhances the development of practical skills by integrating learners' knowledge and skills. This study aimed to investigate the effect of SBE as a preparatory education course when taken prior to a medical student's enrollment in the cadaver dissection course. In the present study, an SBE assuming practical cadaver dissection course was performed in the Clinical Simulation Center. The frequency of injury rates per 1000 h of cadaver dissection course was significantly less in 2017 and 2018 compared to that in 2016. Two years after the implementation of the SBE, average student self-efficacy scores and written examination scores significantly increased, whereas self-contentment scores were relatively unchanged. The results showed that the implementation of SBE decreased the incidence of injuries and improved students' overall self-efficacy scores and increased acquisition of knowledge evident on written examination score. Therefore, SBE as a preparatory education course may effectively promote the combined development of dissection skills and anatomical knowledge in the subsequent fundamental cadaver dissection course. 相似文献
9.
The present experiment examined whether predictability of food acquisition would eliminate the impairment of subsequent escape performance that otherwise resulted from uncontrollability over food acquisition. In pretreatment, the yoked and the yoked-signal groups received response-independent food at the same times as the experimental group acquired it on an FR 5/20 lever-press schedule. However, a pellet presented for the yoked-signal group followed a 1.5-sqc tone, which served as a predictive signal of food. The naive control group received the same clumber of pellets in their home cages in this phase. Results of the escape latency in the subsequent FR 2 shuttling shock-escape test indicated that the predictability of outcome eliminated the escape deficits showed by the yoked-non signal group. This modulating effect of a predictive signal is hypothesized to be due to an overshadowing of uncontrollability by predictability. 相似文献
10.
In two experiments, we examined whether or not a loss of control over food availability would interfere with subsequent two-way shuttle-escape learning. Rats that had experienced loss of control over food delivery were impaired in their acquisition of a shuttle-escape response, relative to the response-contingent and the continuous-reinforcement control rats (in Experiments 1 and 2) and to the lack-of-control and home cage control rats (in Experiment 2). Rats that had received noncontingent food delivery without a prior history of control over food exhibited poorer performance than did the home cage control rats. Moreover, loss of control resulted in a larger interference effect than did lack of control, supporting the view that the learning of response-outcome noncontingency is the main determinant of the interference effect. 相似文献