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The 21st century collection manager encounters serious challenges in collection development (e.g., budget shortages, lack of skilled personnel, lower agency prioritization, and reduced available staff time). This article explores a practical, low-cost solution to these challenges that prevent collection developers from regularly creating/managing adequately balanced collections. It discusses the role of 93 “community-embedded” librarians-in-training to develop contextually situated collections in a graduate course taught seven times in an information sciences program in a southern land grant university. Findings of collection management activity tasks completed during the course provide evidence of accrued tangible outcomes/benefits to motivate collection development librarians and their information agencies collaborate with librarians-in-training in future initiatives. 相似文献
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Like all public libraries, rural public libraries in the Appalachian region can play a significant role in the economic development of their communities. Economic development in rural communities potentially benefit from many of the same resources and services all enjoy at public libraries, including free and public Internet access, space, education, question answering, and materials on many business-related subjects. This article reports survey findings of current activities that rural public libraries perform in one state, namely the state of Tennessee, as a case study to apply the lessons and insights to other parts of the United States. The discussion includes assessment of activities and some recommendations to streamline and stimulate all public libraries in conducting this assistance efficiently. 相似文献
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In this paper we consider the problem of finding a minimum number of nonzero elements of a given nxn matrix on removal of which the resulting matrix can be permuted to an nxn lower triangular matrix using summetric permutations on the rows and columns of the matrix. The problem is related to finding a minimum feedback cutset for the digraph of the matrix. A topological method for finding a minimum feedback cutset for a given digraph is presented. Possible extensions to our work are indicated. 相似文献
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There is minimal research on the cross-cultural needs, priorities, and behaviors of international participants immersed in contemporary culturally alien information environments. Through a quantitative analysis of Internet use patterns of international teaching assistants (ITA) studying in graduate school at a representative university in the United States, the authors discover communication-information convergences in ITAs’ use of the Internet as a “glocal” network, connecting the “global” and “local” dimensions in their everyday lives. The paper identifies dual functions of the Internet considered meaningful to the ITAs in the diaspora, namely: (1) to engage in various communication activities with friends and family in their home countries (the “global”), thereby providing psychological comfort and overcoming social isolation; and (2) to conduct information gathering activities that establish coping mechanisms for ITAs in their new homes in the United States (the “local”). The paper presents empirical data highlighting correlations between communication and information intersections in ITAs’ use of the Internet. Findings extend past Internet research and user studies in traditional communication and information research, which only alluded to these communication-information convergence processes, to better understand how international people use the Internet in present-day cross-cultural contexts of interaction. 相似文献
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Debapriya Bandyopadhyay Haren Baruah Bharat Gupta Shailja Sharma 《Indian journal of clinical biochemistry : IJCB》2012,27(2):164-170
Vascular thrombotic disorders have emerged as a serious threat to our society. Platelet adhesion to fibrinogen, collagen and other platelet activators exposed over the atherosclerotic plaques can trigger platelet signaling events, activate platelets and lead to thrombotic events. Since anticoagulant and thrombolytic treatment strategies are usually associated with serious bleeding complications, preventing platelets adhesion may help to maintain platelets in an inactive state. In this study we tried to find out the effect of Silver nanoparticles, through their interaction with various platelet surface integrins on platelet adhesion on immobilized fibrinogen. Platelets, isolated from anti-coagulated human whole blood sample from healthy donors, were suspended in physiological buffer and each sample was divided into four tubes. In three of them 0.05, 0.5, and 5 μM concentrations of Silver nanoparticles were added, fourth tube served as control. Platelet adhesion on immobilized fibrinogen matrices and integrin mediated cell signaling events were studied in all the four samples. In the present study we show that nanosilver prevent platelet adhesion without conferring any lytic effect on them and effectively prevents integrin-mediated platelet responses in a concentration-dependent manner. 相似文献
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Keni Smita Mehra Raina S. P. Taskar 《Indian journal of clinical biochemistry : IJCB》1992,7(2):147-154
A condition of malnutrition was induced in rats during post weaning stage, by feeding rats with diet containing low protein and high carbohydrate viz. diet with 25% protein [Group I-control rats]. diet with 9% protein [Group II-moderately malnourished] and diet with 6% protein [Group III-severely malnourished]. The rats were sacrified on 21st day. 35th day.42nd day and 90th day. As compared to control rats, somatic weight and pancreatic weight of group II rats was 55 to 80% and 50 to 80% while group III rats were only 50 to 70% and 30 to 40%, respectively. A decrease in cell number, as well as, cell size was evident in malnourished rats from their DNA[10 to 20% of control] and protein [20 to 70% of control] content.. At adulthood, activity of trypsin declined and was 86 and 64% of controls respectively, in groups II and III, while amylase and lipase activities registered a rise at 35 d followed by a decline there after. Malnourished rats were fed the 25% protein diet for 2 weeks after each period of malnutrition, inorder to see the extent of recovery subsequent to induction of a state of malnutrition. Recovery of somatic weight and weight of the pancreas were maximum when the duration of malnutrition was short i.e. following 35 days, recovery being more in group III than group II. Recovery of DNA and protein content was independent of each other. In malnourished rats trypsin activity increased, amylase activity showed a decline, and lipase activity did not respond to the nutritional rehabilitation. 相似文献
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Jagdish Mehra 《Resonance》2011,16(9):836-848
A ‘graduate student’ in biology 相似文献
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Ashavaid TF Raje HS Shah BV Shah SA 《Indian journal of clinical biochemistry : IJCB》2011,26(1):18-21
Single nucleotide polymorphisms in CYP3A5 (A6986G) and MDR-1 (C3435T) genes have been shown to be associated with the pharmacokinetics
of tacrolimus in case of renal transplant recipients. Knowing these genotypes of the recipients before undergoing transplantation,
is therefore essential for physicians to adjust the starting dose of tacrolimus in order to avoid drug induced nephrotoxicity.
We have designed an allele specific PCR method for easier and rapid detection of these polymorphisms. 20 Indian renal transplant
recipients on tacrolimus who developed nephrotoxicity within 1 month of transplantation and 58 Indian non-transplant subjects
having the risk factors for kidney disease i.e. hypertension or diabetes or the family history of these, have been studied
for these SNPs by allele specific PCR method. The data suggest that the heterozygosity of CYP3A5 and mutant allele frequency
of MDR-1 SNP is higher in transplant patients as well as in general population. 相似文献