Combining fiber dissection,plastination, and tractography for neuroanatomical education: Revealing the cerebellar nuclei and their white matter connections          下载免费PDF全文

Hisse Arnts  Michiel Kleinnijenhuis  Jan G.M. Kooloos  Annelieke N. Schepens‐Franke  Anne‐Marie van Cappellen van Walsum 《Anatomical sciences education》2014,7(1):47-55

In recent years, there has been a growing interest in white matter anatomy of the human brain. With advances in brain imaging techniques, the significance of white matter integrity for brain function has been demonstrated in various neurological and psychiatric disorders. As the demand for interpretation of clinical and imaging data on white matter increases, the needs for white matter anatomy education are changing. Because cross‐sectional images and formalin‐fixed brain specimens are often insufficient in visualizing the complexity of three‐dimensional (3D) white matter anatomy, obtaining a comprehensible conception of fiber tract morphology can be difficult. Fiber dissection is a technique that allows isolation of whole fiber pathways, revealing 3D structural and functional relationships of white matter in the human brain. In this study, we describe the use of fiber dissection in combination with plastination to obtain durable and easy to use 3D white matter specimens that do not require special care or conditions. The specimens can be used as a tool in teaching white matter anatomy and structural connectivity. We included four human brains and show a series of white matter specimens of both cerebrum and cerebellum focusing on the cerebellar nuclei and associated white matter tracts, as these are especially difficult to visualize in two‐dimensional specimens and demonstrate preservation of detailed human anatomy. Finally, we describe how the integration of white matter specimens with radiological information of new brain imaging techniques such as diffusion tensor imaging tractography can be used in teaching modern neuroanatomy with emphasis on structural connectivity. Anat Sci Educ. 7: 47–55. © 2013 American Association of Anatomists.  相似文献   

MEDIA COVERAGE AND THE FLOW OF VOTERS IN MULTIPARTY SYSTEMS: THE 1994 NATIONAL ELECTIONS IN HOLLAND AND GERMANY     

Kleinnijenhuis  Fan; Fan  David P. 《Int. Journal of Public Opinion Research》1999,11(3):233-256

Positive news is advantageous for a party, but the effects ofnegative news are less obvious, especially in a multiparty system.One possibility is an indecisionmodel in which negative informationwould push voters to the undecided category. An alternativeis a proportional model in which voters would move to otherparties in proportion to their share of the vote. A third scenariowould correspond to a proximity model in which the shift wouldbe to parties holding viewpoints similar to those of the criticizedparty. The three models were tested using the ideodynamic modelor the 1994 elections in the Netherlands and Germany. The explanatoryvariables were content analysis data obtained daily for majorprint and electronic news media. The dependent variable wasweekly survey data of party preferences of voters. The analysisshowed the proportional model to be the least plausible withthe proximity model being promising. Campaign strategists startingfrom the proximity model will both promote negative news aboutother parties and adopt their issue positions.  相似文献