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Breast displacement has been investigated in various activities to inform bra design, with the goal of minimising movement; however, breast motion during swimming has yet to be considered. The aim was to investigate trunk and breast kinematics whilst wearing varying levels of breast support during two swimming strokes. Six larger-breasted females swam front crawl and breaststroke (in a swimming flume), in three breast support conditions while three video cameras recorded the motion of the trunk and right breast. Trunk and relative breast kinematics were calculated. Greater breast displacement occurred mediolaterally in the swimsuit condition (7.8, s = 1.5 cm) during front crawl and superioinferiorly in the bare-breasted condition (3.7, s = 1.6 cm) during breaststroke, with the sports bra significantly reducing breast displacements. During front crawl, the greatest trunk roll occurred in the sports bra condition (43.1, s = 8.3°) and during breaststroke greater trunk extension occurred in the swimsuit condition (55.4, s = 5.0°); however, no differences were found in trunk kinematics between the three breast support conditions. Results suggest that the swimsuit was ineffective as a means of additional support for larger-breasted women during swimming; incorporating design features of sports bras into swimsuits may improve the breast support provided.  相似文献   
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In the present study, we examined the independent and combined effects of an inspiratory muscle warm-up and inspiratory muscle training on intermittent running to exhaustion. Twelve males were recruited to undertake four experimental trials. Two trials (Trials 1 and 2) preceded either a 4-week training period of 1 × 30 breaths twice daily at 50% (experimental group) or 15% (control group) maximal inspiratory mouth pressure (PImax). A further two trials (Trials 3 and 4) were performed after the 4 weeks. Trials 2 and 4 were preceded by a warm-up: 2 × 30 breaths at 40% PImax. Pre-training PImax and distance covered increased (P < 0.05) similarly between groups after the warm-up (~11% and ~5-7% PImax and distance covered, respectively). After training, PImax increased by 20 ± 6.1% (P < 0.01; d = 3.6) and 26.7 ± 6.3% (P < 0.01; d = 3.1) when training and warm-up were combined in the experimental group. Distance covered increased after training in the experimental group by 12 ± 4.9% (P < 0.01; d = 3.6) and 14.9 ± 4.5% (P < 0.01; d = 2.3) when training and warm-up interventions were combined. In conclusion, inspiratory muscle training and inspiratory muscle warm-up can both increase running distance independently, but the greatest increase is observed when they are combined.  相似文献   
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In this article, The Social Justice Education in Schools (SJES) Project integrates field-based study and existing research to identify five key Principles of Social Justice Education in Schools. An outgrowth of the federally funded Massachusetts Coalition for Teacher Quality and Student Achievement, the SJES Project seeks to positively impact teacher preparation, student achievement, and social justice practice in urban environments. The authors ground their discussion in their partnership with Rodriguez Elementary School, and present specific points of inquiry to facilitate K-12 educators, administrators, and community members' critical reflection on their own school environments. By developing a concrete framework for Social Justice Education in Schools, the authors hope to encourage future empirical research explicitly linking Social Justice Education to student achievement.  相似文献   
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BackgroundConsidering the potential cumulative effects of repetitive head impact (HI) exposure, we need sensitive biomarkers to track short- and long-term effects. Circulating small extracellular vesicles (sEVs) (<200 nm) traffic biological molecules throughout the body and may have diagnostic value as biomarkers for disease. The purpose of this study was to identify the microRNA (miRNA) profile in circulating sEVs derived from human plasma following repetitive HI exposure.MethodsHealthy adult (aged 18–35 years) soccer players were randomly assigned to one of 3 groups: the HI group performed 10 standing headers, the leg impact group performed 10 soccer ball trapping maneuvers over 10 min, and the control group did not participate in any soccer drills. Plasma was collected before testing and 24 h afterward, and sEVs were isolated and characterized via nanoparticle tracking analysis. Next-generation sequencing was utilized to identify candidate miRNAs isolated from sEVs, and candidate microRNAs were analyzed via quantitative polymerase chain reaction. In silico target prediction was performed using TargetScan (Version 7.0; targetscan.org) and miRWalk (http://mirwalk.umm.uni-heidelberg.de/) programs, and target validation was performed using luciferase reporter vectors with a miR-7844-5p mimic in human embryonic kidney (HEK) 293T/17 cells.ResultsPlasma sEV concentration and size were not affected across time and group following repetitive HI exposure. After 24 h, the HI read count from next-generation sequencing showed a 4-fold or greater increase in miR-92b-5p, miR-423-5p, and miR-24-3p and a 3-fold or greater decrease in miR-7844-5p, miR-144-5p, miR-221-5p, and miR-22-3p. Analysis of quantitative polymerase chain reaction revealed that leg impact did not alter the candidate miRNA levels. To our knowledge, miR-7844-5p is a previously unknown miRNA. We identified 8 miR-7844-5p mRNA targets: protein phosphatase 1 regulatory inhibitor subunit 1B (PPP1R1B), LIM and senescent cell antigen-like domains 1 (LIMS1), autophagy-related 12 (ATG12), microtubule-associated protein 1 light chain 3 beta (MAP1LC3B), integrin subunit alpha-1 (ITGA1), mitogen-activated protein kinase 1 (MAPK1), glycogen synthase kinase 3β (GSK3β), and mitogen-activated protein kinase 8 (MAPK8).ConclusionCollectively, these data indicate repetitive HI exposure alters plasma sEV miRNA content, but not sEV size or number. Furthermore, for the first time we demonstrate that previously unknown miR-7844-5p targets mRNAs known to be involved in mitochondrial apoptosis, autophagy regulation, mood disorders, and neurodegenerative disease.  相似文献   
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