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Santosh C. Das Aminu Z. Mohammed Sani U. Al-Hassan Abraham A. Otokwula Uche P. Isichei 《Indian journal of clinical biochemistry : IJCB》2007,22(2):79-83
In order to see the pattern of changes in differential serum lipid and lipoprotein fractions as a risk marker of coronary
complication in paired ‘maternal—neonate’ blood samples in an iodine deficient zone, 26 pregnant women and their corresponding
new born infants at term delivery from the iodine deficient Bassa region of Plateau state, Nigeria were assessed and the results
were compared with those seen in a similar 44 group of women and their newborns assessed in non lodine deficient region of
Jos. The serum thyroid function and lipid and lipoprotein profiles were determined by ‘ELISA’ and ‘enzymatic’ methods respectively.
Urinary iodide excretion level was also measured in 14 pregnant women in Bassa, 23 pregnant women in Jos and 16 non pregnant
control from Jos. Results indicate that the pregnant women assessed in Bassa were iodine deficient (P<0.01) and their thyroid
status was strikingly reduced as reflected by a drop in serum level of T4/TBG ratio (P<0.01) and a rise in TSH (P<0.005) in
comparison to that seen in Jos. There was marked hypertriglyceridaemia and total hypercholesterolaemia (P<0.005), with differential
significant rise in LDL cholestotol fraction (P<0.005) in the women assessed in Bassa as compared to Jos. The HDL cholesterol
however dropped less significantly in the group (P<0.05) with a concurrent marked rise (P<0.001) in the serum ratio of LDL
cholesterol/HDL cholesterol, total cholesterol/HDL cholesterol and triglycerides/HDL cholesterol in the lodine deficient group.
A similar pattern of changes were seen in the corresponding neonates in the Bassa group as compared to Jos group. It is concluded
that the pregnant women and their newborn offsprings living in a longstanding environmental iodine deficiency run a higher
risk of developing coronary complications than those living in non endemic region. It is striking that such newborns surrounded
by a continued state of lodine deficient may at a later adult-period of life develop marked risk of coronary complication
and other features of hyperlipidaemias associated with varying thyroid insufficiency and accompanied iodine deficiency disorders.
Prophylaxis measures as intervention has been highlighted. 相似文献
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Abdulwahab Olanrewaju Issa Kamal Tunde Omopupa Abdullateef Lanre M'Bashir Esther Uche Njoku 《Public Library Quarterly》2013,32(3):228-242
This study examines delinquency at the Oyo State Library Board, Dugbe, Ibadan, Nigeria. The study's objectives were to find out the reasons for delinquency, identify the causes/methods employed, and suggest ways of minimizing its occurrence in the study library. It employs the case study design, sampling nearly 50% of the staff and employing questionnaire, interviews, and personal observations. The findings show that students are the major culprits, who fear others will borrow but fail to return materials. Ways of ameliorating this are suggested, encapsulated in a well-formulated collection development policy to serve as a working document for the library staff. 相似文献
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This study examines the coverage of Africa by the U.S. television networks over a 30-year period, to determine whether the evening news broadcasts pay equal attention to Africa compared to South America and Europe. Also assessed is whether incidents of wars, famine, and public health crises and the increasing importance of Africa's oil, gold, and diamonds on the international market, continue to dominate the U.S. television network evening news coverage of the continent. A content analysis of ABC World News, NBC News, and CBS Evening News shows that coverage of Africa has steadily decreased more than coverage of other regions. The majority of international stories were about Europe while coverage of Africa on all three networks was far less when compared to other regions. Also, conflicts and crises dominated Africa's coverage throughout the 3 decades and stories linked a considerable amount of the news events to a particular U.S. interest. More results and their implications are discussed in detail. 相似文献
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Greg N. Uche 《International Journal of Lifelong Education》2013,32(5):365-374
Offenders, whether they are adults or juveniles, convicts or simply on remand are usually offered some sort of vocational training durir g the period of incarceration. For most prison service establishments, training has been elevated to a position of utmost prominence, so much so that an offender's post‐release career seems to depend largely on the success of training received in prison. Prison vocational training should address the vital aspects of offender rehabilitation and reintegration, and current agitations centre on whether offender should ‘do time’ or ‘use time’ during training sessions. By and large, training should not simply be part of prison routine, but instead should have firm features of an intervention, and also represent a treatment regime. This article discusses a treatment model of prison vocational training for all categories of offenders. The model provides for an initial diagnostic phase of offenders’ work history and training needs, which are carefully analysed in relation to labour market skills requirements. Central to this model is the provision of appropriate job and entrepreneurial skills in conjunction with aftercare services. It also places a high premium on the vocational adjustment of ex‐offenders in society, which must be closely monitored in order that success of the rehabilitation and resettlement processes can be correctly assessed. 相似文献
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Santosh C. Das Uche P. Isichei Aminu Z. Mohammed Abraham A. Otokwula Abiodun Emokpae 《Indian journal of clinical biochemistry : IJCB》2005,20(2):35-42
The effect of iodine deficiency (ID) on thyroid function in African women during pregnancy and postnatal period was examined,
for which very limited information is available. Serum T4, T3, TSH, TBG, thyroxine binding capacity (TBK), free thyroxine index (FT4I=T4/TBK) and T4/TBG were determined by ELISA technique in 32 pregnant women (resident of Plateau state, Nigeria- an ID zone) through pregnancy
upto term delivery, and in 5 women up to 6 weeks post delivery. Urinary iodide level was measured at delivery to determine
the degree of iodine deficiency. Results were matched with a non pregnant control comprising 44 subjects. 5555 birth weights
(BW) of term babies in the region were analysed to determine the prevalence of ‘small for dates’ (SFD) babies in the population.
Results show that the level of serum FT4I was elevated very significantly at late gestation (P<.001) but the women were not hyperthyroid, suggesting a marked disturbance
in binding of T4 with TBG during pregnancy. Five women with SFD babies were found in ‘compensated hypothyroid state’ and showed a significant
depression (p<.01) in serum T4/TBG, T4, FT4I and T3 levels to a low normal range, with a concurrent significant rise (p.<.001) in TSH level (above normal range) throughout pregnancy.
Incidence of SFD babies was higher (p.<.001) in ID zone (Bassa 15.2%) compared to control zone (Jos 9.8%). It is concluded
that a state of maternal ‘subclinical (compensated) hypothyroidism’ during pregnancy possibly plays an important role in the
aetiopathogenesis of SFD babies in Africans. A normal reference range for thyroid parameters at various stages of pregnancy
in healthy African women is established for the first time. 相似文献
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