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1.
β-hydroxy-β-methylbutyrate (calcium: HMB-Ca and free acid: HMB-FA) and α-hydroxyisocaproic acid (α-HICA) are leucine metabolites that have been proposed to improve body composition and strength when combined with resistance exercise training (RET). In this double-blind randomized controlled pragmatic trial, we evaluated the effects of off-the-shelf supplements: α-HICA, HMB-FA and HMB-Ca, on RET-induced changes in body composition and performance. Forty men were blocked randomized to receive α-HICA (n?=?10, fat-free mass [FFM]?=?62.0?±?7.1?kg), HMB-FA (n?=?11, FFM?=?62.7?±?10.5?kg), HMB-Ca (n?=?9, FFM?=?65.6?±?10.1?kg) or placebo (PLA; n?=?10, FFM?=?64.2?±?5.7?kg). The training protocol consisted of a whole-body resistance training routine, thrice weekly for 8 weeks. Body composition was assessed by dual-energy x-ray absorptiometry (DXA) and total body water (TBW) by whole-body bioimpedance spectroscopy (BIS), both at baseline and at the end of weeks 4 and 8. Time-dependent changes were observed for increase in trunk FFM (p?相似文献   
2.
Before the century of great discoveries, and during most of the fifteenth century, the Portuguese developed important commercial activity in the Mediterranean. This is the central issue of this article as seen through two themes: the first is an assessment of the Portuguese organization of Mediterranean trade, with special attention given to the foodstuffs which were, and continued to be, a feature of such trade; and second, is to observe how Portuguese faced competition from others nations’ merchants in the region. The study of these two aspects will provide a better understanding of the re-orientation of Portuguese trade towards the Atlantic.  相似文献   
3.
Science & Education - The current COVID-19 pandemic raises reflection on the new roles of science education in citizen education in a world characterized by civilization risks, derived from the...  相似文献   
4.
In recent years, countries of the Pacific have been moving strongly towards enhancing inclusive educational practices within a previously segregated education system. Through the Pacific Education Development Framework (PEDF) approved by 14 Pacific Island Education Ministers in 2009, the implementation of regional policies of inclusive education is a priority. To ensure that progress is measurable, these countries have been working collaboratively with several Australian institutions to develop a set of contextually appropriate indicators for measuring disability-inclusive education. This article describes the process adopted in developing these indicators and initial findings regarding the key outcomes. The research is guided by three key principles of collaboration, a need for systemic change and ‘nothing about us without us’. The process adopts a three-stage approach which is outlined and key issues and implications discussed.  相似文献   
5.
Abstract

Drag is one of the major factors that influences kayaking performance. To focus on the drag of the kayak’s hull shape and the paddlers’ weight per se, the passive drag (Dp) was measured on a flat-water sprint course for one paddler with added weights. Dp was measured by an electromechanical towing device using a load cell, at incremental and constant velocities from 2.78 to 5.56 m/s. Three kayaks of different sizes and shapes (Nelo® K1 Quattro-M, ML, and L) were used and the paddlers’ body weight was adjusted with weights so the total paddler weight in the kayak was 65, 75, and 85 kg. The mean Dp increased by the power function of D = kvn (mean R2 = .990; SD .006). The Dp went from 21.37?±?1.29 N at 2.78 m/s to 89.32?±?6.43 N at 5.56 m/s. For the two lighter weighted kayaks (65 and 75 kg), the lowest Dp was observed with different kayak sizes (M, ML, or L) depending on the target velocity. The manufacturers suggest that paddlers should select a kayak size according to their body weight to minimise drag; however, the results of this study suggest that target velocities, and thus competition distance should also be factored into kayak selection.  相似文献   
6.
ABSTRACT

To assess the effects of plyometric jump training (PJT) in female soccer player’s vertical jump height, a review was conducted using the data sources PubMed, MEDLINE, Web Of Science and SCOPUS. Only peer-review articles were included. To qualify for inclusion in the meta-analysis, studies must have included (i) a PJT programme of at least 2 weeks, (ii) cohorts of healthy female soccer players with no restriction for age, (iii) a control group, (iv) a measure of countermovement jump (CMJ). The inverse variance random-effects model for meta-analyses was used. From 7,136 records initially identified through database searching, 8 were eligible for meta-analysis, comprising 9 training groups (n = 99) and 9 control groups (n = 94). The magnitude of the main effect was moderate (ES = 1.01 [95%CI = 0.36–1.66], Z = 3.04, p = 0.002). Sub-group analyses were performed (i.e., PJT frequency, duration and total number of sessions), revealing no significant subgroup differences (p = 0.34–0.96). Among the studies included in this review, none reported injury or other adverse effects. In conclusion, PJT is effective in female soccer players for the improvement of vertical jump height. In future, research must identify specific dose–response relationships following PJT, particularly in the long term.  相似文献   
7.
The purpose of this study was to investigate the relationship between movement velocity and relative load in three lower limbs exercises commonly used to develop strength: leg press, full squat and half squat. The percentage of one repetition maximum (%1RM) has typically been used as the main parameter to control resistance training; however, more recent research has proposed movement velocity as an alternative. Fifteen participants performed a load progression with a range of loads until they reached their 1RM. Maximum instantaneous velocity (Vmax) and mean propulsive velocity (MPV) of the knee extension phase of each exercise were assessed. For all exercises, a strong relationship between Vmax and the %1RM was found: leg press (r2adj = 0.96; 95% CI for slope is [?0.0244, ?0.0258], P < 0.0001), full squat (r2adj = 0.94; 95% CI for slope is [?0.0144, ?0.0139], P < 0.0001) and half squat (r2adj = 0.97; 95% CI for slope is [?0.0135, ?0.00143], P < 0.0001); for MPV, leg press (r2adj = 0.96; 95% CI for slope is [?0.0169, ?0.0175], P < 0.0001, full squat (r2adj = 0.95; 95% CI for slope is [?0.0136, ?0.0128], P < 0.0001) and half squat (r2adj = 0.96; 95% CI for slope is [?0.0116, 0.0124], P < 0.0001). The 1RM was attained with a MPV and Vmax of 0.21 ± 0.06 m s?1 and 0.63 ± 0.15 m s?1, 0.29 ± 0.05 m s?1 and 0.89 ± 0.17 m s?1, 0.33 ± 0.05 m s?1 and 0.95 ± 0.13 m s?1 for leg press, full squat and half squat, respectively. Results indicate that it is possible to determine an exercise-specific %1RM by measuring movement velocity for that exercise.  相似文献   
8.

Children with deficits in executive functions (EFs) and impairments in pragmatic language have a range of cognitive and language difficulties that affect their literacy and educational achievements. As deficits in EFs and pragmatic impairments are characteristics of autism spectrum disorders, this study examined the associations between EFs and pragmatic skills in children with high-functioning autism (HFA). Fifteen children with HFA (5–9 years; M?=?7.44, SD 1.21), matched to 15 typically developing peers on age, gender, and non-verbal intelligence participated in the study. Children completed a pragmatic language assessment protocol, and a rating scale of EFs was administered to parents. Our results point to two main findings: children with HFA presented pragmatic difficulties and EFs impairments when compared with typically developing peers; and, as shown by a significant indirect effect of group on pragmatics via EFs, the poor pragmatics skills of HFA children were associated with their EFs difficulties. These findings may be of clinical relevance for children with pragmatic impairments, such as autism spectrum disorders. Future studies are crucial to further investigate the relationship between impaired pragmatics and EFs.

  相似文献   
9.
ABSTRACT

Leucine metabolites may reduce training-induced inflammation; however, there is scant evidence for this assertion. We conducted a double-blind randomized controlled pragmatic trial where 40 male participants were allocated into 4 groups: α-hydroxyisocaproic acid group ([α-HICA], n = 10, Fat-free mass [FFM] = 62.0 ± 7.1 kg), β-hydroxy-β-methylbutyrate free acid group ([HMB-FA], n = 11, FFM = 62.7 ± 10.5 kg), calcium β-hydroxy-β-methylbutyrate group ([HMB-Ca], n = 9, FFM = 65.6 ± 10.1 kg) or placebo group ([PLA]; n = 10, FFM = 64.2 ± 5.7 kg). An 8-week whole-body resistance training routine (3 training sessions per week) was employed to induce gains in skeletal-muscle thickness. Skeletal muscle thickness (MT), one repetition maximum (1RM), interleukin-6 (IL-6), high-sensitivity C-reactive protein (hsCRP) and tumour necrosis factor alpha (TNF-α) were assessed at baseline and at the end of weeks 4 and 8. Time-dependent increases were detected from baseline to week 8 for MT (vastus lateralis: p = 0.009; rectus femoris: p = 0.018), 1RM (back squat: α-HICA, 18.5% ± 18.9%; HMB-FA, 23.2% ± 16%; HMB-Ca, 10.5% ± 13.8%; PLA, 19.7% ± 9% and bench press: α-HICA, 13.8% ± 19.1%; HMB-FA, 15.5% ± 9.3%; HMB-Ca, 10% ± 10.4%; PLA, 14.4 ± 11.3%, both p < 0.001), IL-6, hsCRP (both p < 0.001) and TNF-α (p = 0.045). No differences were found between groups at any time point. No leucine metabolite attenuated inflammation during training. Additionally, backwards elimination regressions showed that no circulating inflammatory marker consistently shared variance with the change in any outcome. Using leucine metabolites to modulate inflammation cannot be recommended from the results obtained herein. Furthermore, increases in inflammatory markers, from training, do not correlate with any outcome variable and are likely the result of training adaptations.  相似文献   
10.
This study evaluated the effect of a multi-component intervention on motor performance (MP) and metabolic risk markers (MRM) in overweight/obese youth. A secondary aim was to examine whether changes in MP are associated to changes in MRM. A 3-month multi-component intervention was performed, consisting of physical exercise sessions (twice/week;1h), nutritional education sessions (once/month), and parental support (twice/week). The sample included 35 volunteers (7–13 y.o), allocated to intervention (INT, n = 17) and control (CONT, n = 18) group. Variables were measured pre (T0) and post intervention (T1). Fasting blood samples were analyzed for MRM. MP tests included the measurement of health related physical fitness components and motor coordination performance (KTK battery). To assess food intake, a 24-hour recall diary was used. GLM-ANCOVA was performed. Standardized scores were calculated for the outcome variables, and multilinear regressions were applied to analyze associations between the key variables. INT group showed improvements in MP, glycolytic and hepatic profiles. After adjustments for MVPA, SB, total intake and maturational stage, negative associations between %ΔMP and %Δglycolytic (β = -.424; 95%CI:-0.343:-0.022), and %Δhepatic scores (β = -.382 95%CI:-0.001:-0.009) were observed. The intervention produced a moderate-to-high effect on the MP and some MRM. Changes in MP were inversely associated with changes in glycolytic and hepatic markers.  相似文献   
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