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Guilherme Giannini Artioli Craig Sale Rebecca Louise Jones 《European Journal of Sport Science》2019,19(1):30-39
AbstractCarnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease. 相似文献
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Kirsty Jayne Elliott-Sale Ashley Graham Stephanie Jane Hanley Sherry Blumenthal Craig Sale 《European Journal of Sport Science》2019,19(1):62-70
AbstractMaternal dietary habits influence maternal and foetal health, representing a pathway for intervention to maximise pregnancy outcomes. Advice on energy intake is provided on a trimester basis, with no additional calories required in the first trimester and an additional 340?kcal?d?1 and 452?kcal?d?1 needed for the second and third trimesters. Energy intake depends on pre-gravid body mass index (BMI); underweight women are recommended an increase of 150, 200 and 300?kcal?d?1 during the first, second and third trimester, normal weight women an increase of 0, 350 and 500?kcal?d?1 and obese women an increase of 0, 450 and 350?kcal?day?1. The recommendations for carbohydrate and protein intake are 175?g?d?1 and 0.88–1.1?g?kgBM?d?1, with no change to fat intake. The number of pre-gravid obese women is rising; therefore, we need to regulate weight in women of childbearing age and limit gestational weight gain to within the recommended ranges [overweight women 6.8–11.3?kg and obese women 5.0–9.1?kg]. This can be achieved using nutritional interventions, as dietary changes have been shown to help with gestational weight management. As pregnancy has been identified as a risk factor for the development of obesity, normal weight women should gain 11.5–16.0?kg during pregnancy. While some research has shown that dietary interventions help to regulate gestational weight gain and promote postpartum weight loss to some extent, future research is needed to provide safe and effective guidelines to maximise these effects, while benefitting maternal and foetal health. 相似文献
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CAD是土木工程专业的学生走向工作岗位必备的最实用的工具。为了满足社会对高等学校培养的专业人才能熟练掌握CAD这门课程的能力的需要,明确CAD课程的教学目标,探寻出目前CAD教学中存在的主要问题,在CAD教学中运用工程实例方法取得较好的教学效果。 相似文献
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Michelle A. Hendricks Elizabeth W. Sale Carol J. Evans Lori McKinley Sherri DeLozier Carter 《Psychology in the schools》2010,47(2):173-183
The effectiveness of a school‐based truancy court intervention in four middle schools in a mid‐sized school district was evaluated. Cumulative data from 185 youth attending a truancy court from 2004 through 2008 were included in the analyses. Results indicated a differential impact of the truancy court intervention depending on truancy severity at baseline. The intervention was most successful in increasing attendance for students with severe truancy, but had limited impact on students with moderate truancy, and no impact on mild truancy. The intervention did not result in improved school attachment or grade point averages, nor did it significantly reduce discipline offenses. Furthermore, the aftercare intervention, consisting of regular meetings with an authority figure (e.g., a juvenile officer), was only effective at maintaining truancy court attendance gains for students with severe truancy at baseline, although it was associated with a substantial decrease in discipline offenses for all groups. These results suggest that truancy courts similar to the one described here may have an impact on truancy for severely truant students, but may have a limited effect on students with mild or moderate truancy. © 2009 Wiley Periodicals, Inc. 相似文献
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Daniel Martin Simon Cooper Craig Sale Graham Compton 《Journal of sports sciences》2015,33(11):1159-1165
The purpose of this study was to determine the reliability of maximum voluntary isometric force (MVIF), cross-sectional area (CSA) and force per unit CSA measures, of the first dorsal interosseus (FDI) muscle, using a custom-built dynamometer and ultrasonography. Twenty-seven participants completed MVIF and CSA measurements on two separate occasions under the same conditions. Reliability was determined using paired samples t-tests, systematic bias ratio and ratio limits of agreement (RLoA), intra-class correlation (ICC) and coefficient of variation (CV). MVIF of the FDI muscle (mean ± s; 31.8 ± 7.6 N and 31.6 ± 7.3 N) was not different between trials (P = 0.63); RLoA between trials were 1.00 ×/÷ 1.09, ICC = 0.990 and CV = 3.22%. CSA of the FDI muscle (22.6 ± 6.9 and 22.9 ± 6.9 mm2) was also not different between trials (P = 0.31); RLoA between trials were 0.98 ×/÷ 1.19, ICC = 0.979 and CV = 6.61%. Force per unit CSA was not different between trials (1.49 ± 0.43 and 1.46 ± 0.44 N·mm2; P = 0.18), RLoA were 1.02 ×/÷ 1.17, ICC = 0.985 and CV = 5.76%. The techniques used to determine MVIF and CSA of the FDI muscle were reliable and can be combined to calculate force per unit CSA. 相似文献
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