Zusammenfassung. Die intelligente Ressourcenadaption ist eine der gro?en Herausforderungen für die n?chste Generation mobiler Navigationssysteme.
Da man typischerweise mehrere Fortbewegungsarten oder Verkehrsmittel kombinieren muss, um an einen Zielort zu gelangen, muss
sichergestellt werden, dass mobile, allgegenw?rtige Navigationshilfen dies über eine jeweils situationsangepasste Benutzerschnittstelle
unterstützen. Der notwendige Wechsel zwischen verschiedenen Positionierungstechnologien soll für den Endbenutzer m?glichst
unbemerkt bleiben. Im folgenden wird ein hybrides Personennavigationssystem vorgestellt, das die in bestimmten Fortbewegungssituationen
verfügbaren Positionierungstechnologien und deren Genauigkeit optimal nutzt, um die Pr?sentation der Wegbeschreibung auf verschiedene
Endger?te und Ausgabemodalit?ten sowie die kognitive Ressourcenlage des Benutzers zu adaptieren.
Eingegangen am 28. Februar 2001 / Angenommen am 8. August 2001 相似文献
The first natural history collections opened to the public were inspired by a sense of curiosity and wonder about the products of nature. They were ‘cabinets of curiosities’ that offered a first-hand interaction between owner and visitors. Nowadays, these two facets of the museum experience—dialogue and wonder—have been lost, in part, due to the information overload coming via the media and the impersonal nature of the museum visit. This paper offers some reflections on the evolution of the museum visit, suggests some ways to rediscover this ‘sense of wonder’ and provides ideas on how to promote two-way communication with museum visitors. Two examples of exhibitions are offered as illustrations of the points discussed. 相似文献
Screening programs for colorectal cancer (CRC) are mainly based on a first-line fecal immunochemical test for hemoglobin (FIT). Fecal M2-type pyruvate kinase (M2-PK) has been evaluated in clinical settings showing promising results for early CRC detection. However, the impact of fecal M2-PK assessment on the performance of first-round CRC screening programs is not known. We investigated whether fecal M2-PK alone or in combination with FIT may improve CRC screening efficacy in the general population.
Materials and methods
A total of 1027 asymptomatic subjects (median age 66 [59-74] years; females 504 [49.1%]), identified through the general practitioners’ rosters, were invited for the collection of 2 fecal samples for FIT and M2-PK evaluation. Participants with at least positive one fecal test were referred for colonoscopy. Quality indicators for screening performance were calculated and analyzed using Fisher’s exact test.
Results
Overall, 572 subjects underwent both FIT and M2-PK assessment (participation rate 55.7%): 93 participants showed positive results for at least one test (positivity rate 16.3%). Only 10 patients were positive for both tests. Attendance rate to colonoscopy was 86.0% and a total of 65 adenomas and 7 cancers were detected. Combined use of FIT and fecal M2-PK permitted the identification of 18 more neoplasm (25%) without improving colonoscopy workload, as deduced by the comparable number needed to scope (P = 0.402).
Conclusion
The addition of M2-PK testing to FIT offers the potential to detect additional neoplasms that either do not bleed or only bleed intermittently without reducing participation rate and without increasing endoscopy workload.Key words: biomarker, colorectal cancer, occult blood, M2-type pyruvate kinase, screening相似文献
Testing is one of the important tasks in any multi-step sport programme. In most ball games, coaches assess motor, physical and technical skills on a regular basis in early stages of talent identification in order to further athletes’ development. The purpose of the study was to investigate anthropometric variables and vertical jump heights as a free throw effectiveness predictor in water-polo players of different age groups. Two hundred and thirty-six young (10–18 years) male water-polo players partitioned into three age groups underwent anthropometric variables’ measures and squat- and countermovement-jump tests, and performed water-polo free throws. Anthropometric variables, vertical jump heights and throw speed – as a proxy for free throw effectiveness – resulted different over age groups. Particularly, throw speed changed from 9.28 to 13.70 m · s?1 (+48%) from younger to older players. A multiple-regression model indicated that body height, squat-jump height and throw time together explain 52% of variance of throw speed. In conclusion, tall height, high lower limb power and throwing quickness appeared to be relevant determinants for effective free throws. Such indications can help coaches during talent identification and development processes, even by means of novel training strategies. Further research is needed over different maturity statuses. 相似文献
Psychobiology is an area of knowledge that deals with the biological basis of behaviour. Its concretion as a specific area of study originates in the confluence and development of other areas such as physiological psychology, experimental and comparative psychology, ethology, biology and the neurosciences. For some, psychobiology would be that part of the neurosciences that deals with the study of the processes of emotion, motivation, cognition and learning. Others are of the opinion that it covers a much wider area, and that its objective is rooted in the study of all biological mechanisms that govern behaviour — and these, undertaken from a philogenetic and ontogenetic perspective.
In the last decade, we have witnessed the creation of psychobiology departments throughout the world. These departments participate in the teaching of faculties of medicine, psychology, biology and zoology. In some universities, these departments even contribute to the teaching imparted by the faculties of philosophy and educational sciences. Sooner or later, the universities teaching at a distance had to consider the creation of departments of psychobiology to attend to the up‐dating of the curriculum of diversive faculties.
In the National University of Education at a Distance, U.N.E.D. (Madrid, Spain) the teaching of psychobiology is entrusted to a department of the same name which started during the academic year of 1982–83. Even though the experience is very short to be able to advance a complete evaluation, the difficulties encountered in the organization of the form and content of different courses imparted by the department of psychobiology (D.P.) could be useful to the reader. Therefore, these difficulties must be understood within the educational model of teaching at a distance at U.N.E.D. 相似文献