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1.
The format of cycling time trials in England, Wales and Northern Ireland, involves riders competing individually over several fixed race distances of 10–100 miles in length and using time constrained formats of 12 and 24 h in duration. Drawing on data provided by the national governing body that covers the regions of England and Wales, an analysis of six male competition record progressions was undertaken to illustrate its progression. Future forecasts are then projected through use of the Singular Spectrum Analysis technique. This method has not been applied to sport-based time series data before. All six records have seen a progressive improvement and are non-linear in nature. Five records saw their highest level of record change during the 1950–1969 period. Whilst new record frequency generally has reduced since this period, the magnitude of performance improvement has generally increased. The Singular Spectrum Analysis technique successfully provided forecasted projections in the short to medium term with a high level of fit to the time series data.  相似文献   
2.
This article explores an understanding of learning as authentic enquiry and language as a social practice of meaning construction as the theoretical perspectives underlying an educational initiation beyond mainstream tertiary language education. With a general ethnographic approach and relying on multiple data sources, we investigate critical practices of teaching medical English in an Iranian university and illustrate a contextualized instance of enquiry-based language learning that embodies enquiry and discovery in two senses: students’ research and learning about the content for oneself, and moving away from spoon-feeding views of academic language education to experience language in real social contexts. On this basis, we argue for stepping beyond predetermined content-based approaches to university language teaching and call for living the language that is being learned, which involves enquiring, experiencing, discovering, challenging, and owning it.  相似文献   
3.
The search for fairness in language testing is distinct from other areas of educational measurement as the object of measurement, that is, language, is part of the identity of the test takers. So, a host of issues enter the scene when one starts to reflect on how to assess people's language abilities. As the quest for fairness in language testing is still in its infancy, even the need for such a research has been controversial, with some (e.g., Davies, 2010) arguing that such research is entirely in vain. This paper will provide an overview of some of the issues involved. Special attention will be given to critical language testing (CLT) as it has had a large impact on language testing research. It will be argued that although CLT has been very effective in revealing the ideological and value implications of the constructs of focus in language testing, extremism in this direction is not justified.  相似文献   
4.
Social informatics research offers insights into the relationship between information technologies and social contexts. However, the material roles of information technologies, and their interplay with the agentic work of social actors, have not been addressed. Drawing on a field study of 37 mobile knowledge workers, we examine the dual material roles (enabling and constraining) played by information technologies in their work practices. We also investigate how these workers exert agency by fashioning multiple information technologies into a functioning digital assemblage. Although information technologies provide consequential affordances that enable mobilization of work across spaces and times, they simultaneously present design-driven, local, organizational, and temporal technological constraints that require mobile knowledge workers to engage in “configuration work” to make information technologies function effectively. Building on a sociomaterial perspective, we further discuss the interplay of information technologies and work practices enacted by mobile knowledge workers, in which both human and technological agency are materialized.  相似文献   
5.
Measurement of optical properties of skin is an expanding and growing field of research. Recent studies have shown that the biological tissue, especially skin, changes the polarization state of the incident light. Using this property will enable the study of abnormalities and diseases that alter not only the light intensity but also its polarization state. In this paper we report an experimental study for measuring changes of polarization state of the light scattered from a phantom similar to a sample model of scattering skin. Using the notation of Stokes vector for the polarized light and Mueller matrix for the sample with its polarization properties, we have shown that some elements of the matrix were particularly sensitive to the changes of the polarization-altering physical properties of the scatterers within the phantom.   相似文献   
6.
A new programming course to prepare novices for the traditional Computer Science 1 course (CS1) is proposed. The course uses 3D interactive animation in a novice-friendly environment to introduce object-oriented programming concepts and help students develop problem-solving skills. Pedagogical issues are presented that involve the use of visualization and graphics concepts, the notion of state, and programming language concerns. A study of practice and experimentation with this course is underway. The evaluation plan for this study is briefly described and some early results are summarized, along with observed benefits and concerns.  相似文献   
7.
The objective of the investigation was to study the application of ultrasound reactor technology (USRT) as a disinfectant for reduction of fungi from sewage effluent. Fungi are carbon heterotrophs that require preformed organic compounds as carbon sources. USRT is an attractive means to improve water quality because of the system simplicity and no production of toxic by-products. An ultrasound reactor produces strong cavitation in aqueous solution causing shock waves and reactive free radicals by the violent collapse of the cavitation bubble. These effects should contribute to the physical disruption of microbial structures and inactivation of organisms. There was significant reduction in fungal growth, with decreased fungal growth with increasing USRT. In this study, ultrasound irradiation at a frequency of 42 kHz was used to expose suspensions of fungi to evaluate the disinfection efficacy of the ultrasound reactor. Also, this study showed that in this system more than 99% reduction of sewage fungi was achieved after 60 min.  相似文献   
8.
Brucellosis, a zoonosis caused by four species of brucella, has a high morbidity. Brucella melitensis is the main causative agent of brucellosis in both human and small ruminants. As an alternative to conventional antibiotics, medicinal plants are valuable resources for new agents against antibiotic-resistant strains. The aim of this study was to investigate the usage of native plants for brucellosis treatment. For this purpose, the anti-brucella activities of ethanolic and methanolic extracts of Salvia sclarea, Oliveria decumbens, Ferulago angulata, Vitex pseudo-negundo, Teucrium polium, Plantago ovata, Cordia myxa, and Crocus sativus were assessed. The activity against a resistant Br. melitensis strain was determined by disc diffusion method at various concentrations from 50–400 mg/ml. Antibiotic discs were also used as a control. Among the evaluated herbs, six plant (Salvia sclarea, Oliveria decumbens, Ferulago angulata, Vitex pseudo-negundo, Teucrium polium, and Crocus sativus) showed anti-brucella activity. Oliveria decumbens was chosen as the most effective plant for further studies. A tested isolate exhibited resistance to tetracycline, nafcillin, oxacillin, methicillin, and colistin. Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values for Oliveria decumbens against resistant Br. melitensis were the same (5 mg/ml), and for gentamicin they were both 2 mg/ml. Time-kill kinetics for a methanolic extract of Oliveria decumbens was 7 h whereas for an ethanolic extract it was 28 h. Also, Oliveria decumbens extracts showed a synergistic effect in combination with doxycycline and tetracycline. In general, the similar values of MIC and MBC for Oliveria decumbens suggest that these extracts could act as bactericidal agents against Br. melitensis. In addition to Oliveria decumbens, Crocus sativus and Salvia sclarea also had good anti-brucella activity and these should be considered for further study.  相似文献   
9.
Cinnamon has been used as an anti-diabetic agent for centuries but only in recent few years its mechanism of action has been under investigation. Previous studies showed that cinnamon might exert its anti-diabetic effect via increasing glucose transporter isotype-4 (GLUT4) gene and glycoprotein contents in fat cells. To study if hydro-alcoholic cinnamon extract (HACE) enhances GLUT4 translocation from intracellular compartments of nuclear or endoplasmic reticulum membranes (N/ER) into the cytoplasmic membrane (CM). C2C12 myoblastic cell line were seeded in DMEM plus 20 % FBS and differentiated to myotubes using 2 % horse serum. After myotubes formation, 100 or 1,000 μg/ml HACE, as intervention, and as control 1 % DMSO were added for 3 h. Cells were washed and homogenized followed by ultracentrifuge fractionation, protein separation by SDS-PAGE and GLUT4 detection using semi-quantitative Western blotting. Data analysis was done by two-independent samples t test for comparison of mean ± SD of GLUT4 percent in categories. GLUT4 contents were higher in CM of groups 100 and 1,000 μg/ml HACE and lower in 1 % DMSO treated myotubes (CI = 0.95, P < 0.05). For N/ER reverse results were obtained (CI = 0.95, P < 0.05). As our results have shown HACE induces GLUT4 translocation from intra-cell into cell surface. We conclude that cinnamon maybe a choice of type-2 diabetes mellitus treatment because its extract enhances GLUT4 contents in CM where it facilitates glucose entrance into the cell. However it is necessary to trace the signaling pathways which are activated by HACE in muscular tissue.  相似文献   
10.
This study investigates on a strong correlation between complex network (CN) controllability (characterized by the number of required driver nodes) and graph symmetry (described by automorphism groups) in undirected and unweighted networks. Based on the properties of permutation products of elementary automorphisms, novel necessary conditions for CN controllability are presented which are computationally more effective than previous method. In addition, a novel index of symmetry is proposed upon which a more meaningful understanding of symmetry impact on CN controllability can be comprehended. Based on this new index, a modification strategy is suggested aiming to satisfy CN controllability with a lower number of driver nodes. The study shows that the proposed modification approach can result in a minimal set of driver nodes with a reasonable computational complexity. Further, the critical components of complex networks, in terms of their impact on the number of required driver nodes, are identified. The results of the proposed methodologies have been verified for several synthetic and real test systems including small, medium, and large power networks.  相似文献   
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