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Jonathan S. Jones Anna-Lynne R. Adlam Abdelmalek Benattayallah Fraser N. Milton 《Child development》2022,93(3):815-830
Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed. 相似文献
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Guilherme Giannini Artioli Craig Sale Rebecca Louise Jones 《European Journal of Sport Science》2019,19(1):30-39
AbstractCarnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease. 相似文献
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Ian McNay 《Higher Education Quarterly》2002,56(3):303-315
A small pilot project suggests that the governance of smaller colleges differs significantly from that of large universities, including the former polytechnics which were incorporated at the same time. The differences do not only relate to size, even though small size allows greater contact between governors and academic activities in their role in relation to 'the general educational character' of an institution. Small size also creates possibilities of a 'drift' to a greater role for governors in management rather than governance, and key issues emerge of role boundaries and relationships with staff. Smaller colleges have other factors affecting governance. Some have particular specialisms – music, art, land–based industries and so on – with their own cultures, shifting employment contexts, and considerable overlap between professionals inside and outside the colleges. The history of some as church colleges also continues to have influence. In general, their size allows a more 'familial' climate in decision–making, but that, too, has strengths and weaknesses. 相似文献
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Ian Wells 《British Journal of Special Education》1991,18(2):63-66
Responsibility for pupils with severe learning difficulties in Northern Ireland was only recently taken by the education authorities. The findings of research into the school leaving arrangements are described by Dr Ian Wells, senior research officer with the Northern Ireland Council for Educational Research (NICER), Belfast. 相似文献
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One of the highest priorities in today's hospitals is the provision of quality care to patients. The medical librarian has an increased responsibility to furnish quality information to the medical staff. Traditional methods of reference service continue to work well, but it is increasingly important for librarians to become more directly involved in hospital quality assurance (QA) activities. Occurrence screening is one system of QA where the librarian can make a difference. 相似文献