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1.
Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed.  相似文献   
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Early childhood is a sensitive period for learning and social skill development. The maturation of cerebral regions underlying social processing lays the foundation for later social-emotional competence. This study explored myelin changes in social brain regions and their association with changes in parent-rated social-emotional development in a cohort of 129 children (64 females, 0–36 months, 77 White). Results reveal a steep increase in myelination throughout the social brain in the first 3 years of life that is significantly associated with social-emotional development scores. These findings add knowledge to the emerging picture of social brain development by describing neural underpinnings of human social behavior. They can contribute to identifying age-/stage-appropriate early life factors in this developmental domain.  相似文献   
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As medical programs place increasing importance on competency-based training and surgical simulations for residents, anatomy laboratories, and body donation programs find themselves in a position of adapting to changing demands. To better assess the demand for “life-like” cadaveric specimens and evaluate the possible impacts that competency-based medical education could have upon the body donation program of McGill University, Canada, the authors tracked, over the course of the last 10 years, the number of soft-embalmed specimens, along with the number of teaching sessions and the residents enrolled in competency-based programs that are using cadaveric material. The results reveal that the number of soft-embalmed specimens used within residency training increased from 5 in 2009 to 35 in 2019, representing an increase from 6% of bodies to 36.5% of the total number of body donors embalmed in this institution. Correspondingly, the number of annual teaching sessions for residents increased from 19 in 2012 to 116 in 2019. These increases in teaching are correlated with increasing number of residents enrolled in competency-based programs over the last 3 years (Pearson r ranging from 0.9705 to 0.9903, and R2 ranging from 0.9418 to 0.9808). Those results suggest that the new skill-centered curricula which require residents to perform specific tasks within realistic settings, exhibit a growing demand for “life-like” cadaveric specimens. Institutions’ body donation programs must, therefore, adapt to those greater need for cadaveric specimens, which presents many challenges, ranging from the logistical to the ethical.  相似文献   
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Research in Higher Education - Given the significant need to increase and diversify graduate enrollments within computing fields, it is vital to understand what shapes students’ pathways to...  相似文献   
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体医融合和非医疗健康干预可以有效促进疾病管理与健康服务模式的形成,但体医融合项目治理初期仍然受到理念融合、体医融资、部门协同等因素的影响。该文以病毒、人体免疫与体育运动的体医融合关系视角,依据共生理论对体医融合项目的风险治理逻辑进行了阐述。采用文献资料法、数理统计法等对体医融合项目风险治理的相关个案进行了整理,并基于NVIVO11.0质性分析软件对体医融合个案进行识别分析,构建了体医融合项目风险治理的影响因素评价指标体系,包括13个一级指标30个二级指标。最后提出了体医融合项目风险治理的路径选择(1)将体医融合理念提升至构建公共卫生保障体系战略的高度;(2)落地变现体医融合项目购买方案;(3)打造政府精准购买体医融合项目区块链。  相似文献   
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Abstract

Supporting global health priorities through the development of robust health science librarianship partnerships is of significant importance. Increased demand for synthesizing evidence-based information, collating quality resources, and increasing research productivity to improve human health requires integration of library and information science skills and expertise. The Health Sciences Library (HSL) at the University of North Carolina at Chapel Hill (UNC), exists to be an indispensable partner in health information and knowledge, teaching and learning, and research. As global efforts at UNC expanded, the HSL sought to ensure that our global engagement strategy and integration were aligned with campus priorities and partner needs. The HSL created a global research partnership plan: identify resources that improve efficiency, increase access to information, build in-country capacity and expertise—all while strengthening collaborations across multiple countries. Creating a meaningful and sustainable engagement strategy was central to envisioning our path forward and can be used as a framework for consideration by librarians in similar settings.  相似文献   
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  • Scientific publication has been a key part of the scientific method since the inception of Philosophical Transactions in 1665.
  • The scientific publications industry has grown exponentially along with science, incorporating technological innovations along the way, and adapting journal processes and practices to changing needs of science as it matured.
  • Of all the technological innovations over more than 300 years, the move to online journals may be the most significant, making open access to content practical for the first time.
  • The open‐access movement is disrupting the economics of journal publishing, which is hoped will make the industry more competitive: the ability of the publications industry to adapt to open access will be a measure of its resilience.
  • The demand for articles published in reputable journals continues to grow as readers trust the credibility of peer reviewed journal articles, and good authors value the prestige of publishing in the best journals.
  • It is difficult to predict what new functionalities may be included in articles of the future or what additional services publishers and editors will provide, but there is every reason to believe that scientific journal articles are here to stay.
  相似文献   
10.
Seventy-nine 3-year olds and their mothers participated in a laboratory-based task to assess maternal hostility. Mothers also reported their behavioral regulation of their child. Seven years later, functional magnetic resonance imaging data were acquired while viewing emotional faces and completing a reward processing task. Maternal hostility predicted more negative amygdala connectivity during exposure to sad relative to neutral faces with frontal and parietal regions as well as more negative left ventral striatal connectivity during monetary gain relative to loss feedback with the right posterior orbital frontal cortex and right inferior frontal gyrus. In contrast, maternal regulation predicted enhanced cingulo-frontal connectivity during monetary gain relative to loss feedback. Results suggest parenting is associated with alterations in emotion and reward processing circuitry 7–8 years later.  相似文献   
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