Long-term endurance training increases serum cathepsin S and decreases IL-6 and hsCRP levels     

Michael Sponder  Ioana-Alexandra Campean  Michael Emich  Monika Fritzer-Szekeres  Brigitte Litschauer  Jutta Bergler-Klein 《Journal of sports sciences》2017,35(21):2129-2134

Cathepsin S (CS) was shown to play a key role in cancer progression, atherosclerosis, heart valve disease, insulin resistance and diabetes mellitus. The present prospective study aimed to investigate the influence of sports on CS, interleukin-6 (Il-6) and high-sensitivity C-reactive protein (hsCRP) levels.

Ninety-eight of 109 participants completed the study. Ergometries were performed at baseline and after 8 months to evaluate/quantify the performance gain. Blood samples were taken at baseline and every 2 months. CS was measured by ELISA (enzyme-linked immunosorbent assay). Compared to the control group (mean performance gain ?3.41 ± 4.62%) we observed a significant physical-activity-induced increase of CS levels (3.45–3.73 ng · ml^?1; P = 0.027) and a significant decrease of Il-6 (2.43–1.91 pg · ml^?1; P = 0.031) and hsCRP-levels (0.11–0.09 mg · dl^?1; P = 0.001) in the intervention group (mean performance gain: 12.13 ± 6.32%). Furthermore, the tendency of the progression was significant for CS and Il-6 (P = 0.002/0.033).

We could show a significant sports-induced decrease of the classic inflammation parameters hsCRP/Il-6, probably expressing a downregulation of permanently prevalent inflammation processes. Simultaneously CS levels increased significantly. Our results show that increasing CS amounts are not simply to equal with an enhanced inflammation status and might even have beneficial effects on inflammation and angiogenesis.  相似文献   

Teacher Empathy and Attitudes Towards Individuals with Disabilities     

Monika Parchomiuk 《International Journal of Disability, Development & Education》2019,66(1):56-69

The article presents research results of a study aimed at determining the correlation between empathy understood as a personality disposition and general attitudes towards individuals with disability. The sample consisted of 300 special education teachers working with persons with intellectual disabilities in primary and secondary schools and institutions of rehabilitation, and 280 general education teachers working with able-bodied students in primary and secondary schools. Two instruments were used: Empathic Understanding of Other People Questionnaire, and the Scale of Attitudes towards Individuals with Disability. In the group of special education teachers, only Syndrome 2 of empathy was statistically significant for shaping the attitudes, whereas among teachers, Syndromes 1, 3 and 4 were significant. In Syndromes 1, 2 and 4, including the highest level of emotional, cognitive, motivational and communication aspects of empathy, the correlations were positive as expected. In the case of Syndrome 3, including the considerable level of cognitive empathy, the correlation was negative.  相似文献   

WOMEN IN DISTANCE STUDY ‐ WOMEN STUDENTS AT THE FERNUNIVERSITAT IN HAGEN (FEDERAL REPUBLIC OF GERMANY)     

Michaele Hetzel  Monika Schneidereit  Angela Schuch 《Higher Education in Europe》1981,6(3):18-22

The authors take up the hypothesis that distance education was also meant to facilitate the access of women to higher education. Recent studies carried out at the University for Distance Education at Hagen show that results do not always match expectations. By analysing in detail the causes for this partial failure, the authors come forward with some remedial proposals.

The authors are all members of the staff of Hagen University.  相似文献   

Effect of Tara (Caesalpinia spinosa) Pod Powder on the Oxidation and Colour Stability of Pork Meat Batter During Chilled Storage     

Monika Skowyra  Urszula Janiewicz  Anna Marietta Salejda  Gra?yna Krasnowska  María Pilar Almajano 《Food Technology and Biotechnology》2015,53(4):419-427

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Perspective Paper: Assessing Air Quality as Part of a Physical Therapy Plan of Care     

Dennis C. Sobush  Monika Burrescia 《Cardiopulmonary Physical Therapy Journal》2011,22(1):20-24

Purpose: The purposes of this clinical perspective paper are (1) to expand physical therapists’ awareness to the topic of air quality as a health priority when providing professional services; and (2) to provide templates for screening the indoor clinical environments and patient profiles to avert respiratory exacerbations, especially in persons with asthma. Summary of Key Points: The location where a physical therapist practices determines the air quality indices to which a person is exposed. Poor indoor air quality can expose a person to even greater compromise of respiration (ie, Sick Building Syndrome) than outdoor air quality secondary to an array of factors like building materials, the ventilation exchange rate of an enclosed space, chemicals used in cleaning, and humidity. Statement of Conclusions: Extrinsic (ie, environmental) and intrinsic (eg, pre-disposition to airway hypersensitivity) factors must be accounted for by physical therapists to safeguard their patients and themselves from experiencing respiratory compromise and/or distress as a result of a treatment session or their place of employment. Recommendations: Efforts to screen indoor environments for potential triggers and patient risk profiles for abnormal airway reactivity should routinely be undertaken. Individualized Action Plans should be prospectively prepared and readied for implementation when warranted.Key Words: asthma, Sick Building Syndrome, indoor air quality, respiratory impairment  相似文献   

Pathways From Childhood Sociomoral Sensitivity in Friendship,Insecurity, and Peer Rejection to Adult Friendship Quality     

Annekatrin Steinhoff  Monika Keller 《Child development》2020,91(5):e1012-e1029

Across the life span, friendship is an important component of people’s support networks. This article explores the developmental roots of adult friendship intimacy and satisfaction, taking into consideration the early interplay between sociomoral sensitivity in friendship, insecurity in peer contexts, and peer rejection. Data (N = 176) came from the longitudinal study “Individual Development and Social Structure.” Respondents were surveyed repeatedly from age 7 to 37 years. Autoregressive cross-lagged panel models show that sociomoral sensitivity in friendship protects adolescents from peer rejection and is reciprocally associated with insecurity. Childhood and adolescent sociomoral sensitivity antecede early adult friendship intimacy, which, in turn, antecedes friendship satisfaction in mid-adulthood. The findings indicate a sequence of pathways from sociomoral sensitivity developed early in life to friendship quality in adulthood.  相似文献   

Block scheduled versus traditional biology teaching—an educational experiment using the water lily     

Christoph Randler  Konstanze Kranich  Monika Eisele 《Instructional Science》2008,36(1):17-25

In this study, we compared a traditional teaching sequence (four distinct lessons) with a block schedule dealing with the ecological adaptations of the water lily. The educational unit contained original plant material and both experimental groups received the same tasks and working sheets. Pupils worked together in groups of three to four pupils in a self-regulated manner, carrying out hands-on experiments. However, both groups differed in their time schedule (four distinct lessons of 45 min versus one block of 180 min). Pupils from the traditionally scheduled education performed significantly better in the immediate post-test while these differences merged in retention.  相似文献   

Diagnostic and prognostic value of the urinary excretion of beta-aminoisobutyric acid in patients with urinary bladder cancer     

R. L. Gupta  K. Ramachandran  Monika  J. S. Chowhan 《Indian journal of clinical biochemistry : IJCB》1996,11(1):59-61

Urinary excretion of beta-aminoisobutyric acid (BAIB), was determined in 28 active and 12 inactive bladder cancer patients. Mean excretion of BAIB was higher in active cancer patients-187.8 mg/24 hours whereas it was 120.4 mg/24 hours in inactive cancer patients. The increased BAIB excretion in both disease groups was independent of tumour stage. BAIB appears to be a useful diagnositic aid in the assessment of bladder cancer patients.  相似文献   

NEGOTIATING POLITICIANS’ RESPONSIBILITIES IN NEWS INTERVIEWS     

Mats Ekström  Monika Djerf-Pierre  Bengt Johansson  Nicklas Håkansson 《Journalism Practice》2016,10(8):983-1004

News interviews are contexts in which political responsibilities are articulated and negotiated. Although the accountability interview is recognized as a commonsense practice in journalism, and the research on political interviews is substantial, it partly remains to explore how responsibilities are negotiated in different forms of questioning in journalism. This study investigates three generic forms of questioning: accountability questioning, the clarifying of promises, and the principal assessments. Key features of the different forms are specified. The empirical study investigates how the questionings are performed in news on industrial crises in Sweden, in the different political regimes in the 1970s and the 2000s. The data consist of 27 news interviews with the formally responsible Ministers. The method is based on Conversation Analysis and includes detailed analyses of questions and answers. The study shows (1) how the forms of questioning differ when it comes to the action agenda and in how responsibilities are invoked and negotiated; (2) how the questionings tend to reproduce particular expectations of Governmental interventions; (3) how increased assertiveness and adversarialness in interviewing coincide with reduced expectations of political responsibilities.  相似文献   

Validity of Holland’s theory in adolescence: evidence from a Slovak sample     

Martončik  Marcel  Kačmárová  Monika  Hruščová  Eva  Magáčová Žilková  Ivana  Kravcová  Michaela 《International Journal for Educational and Vocational Guidance》2020,20(3):543-565

The underlying calculus assumption of Holland’s theory was tested in two samples of primary school students (N₁ = 400 and N₂ = 250) with an average age of 13.86 and 14.14 years, respectively. Both exploratory and confirmatory multidimensional scaling and Hubert and Arabie’s randomization test of hypothesized order relations were calculated. The circular spatial arrangement of RIASEC types was not confirmed in either of the two samples. The study discusses possible causes of the inappropriateness of using Holland’s model in an adolescent sample.

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