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Tertiary Education and Management - External quality audits have been introduced in many parts of the world including Asia Pacific, Asia, Africa, Europe, and the Middle East. While external quality... 相似文献
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The Nobel Prize in Chemistry, 2012 has been awarded to Robert J Lefkowitz and Brian K Kobilka for their studies on G-Protein Coupled Receptors (GPCRs). GPCRs are receptor proteins present on the cell surface, which are involved in sensing molecules outside the cell and initiating a cellular response. They can sense a wide variety of ligands ranging from light to hormones and small peptides, triggering various physiological responses. Today we understand the molecular mechanisms by which these receptors work largely due to the contributions of Lefkowitz and Kobilka. Owing to the role of GPCRs in cell communication and involvement in various disease conditions, they are targets of over 40% of current drugs in the market. These findings have not only revealed how GPCRs work, but have also made a huge impact on the field of GPCR-associated drug discovery. 相似文献
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Private for-profit higher education has grown rapidly in many parts of the world. This growth is attributed to many factors, including a broadening of the student population and the recognition that wider access to higher education will be economically beneficial to individuals, governments and society as a whole. In Australia, the number of students in private for-profit higher education is rising, with dramatic projections for the next 10 years. The Australian government has set a target to increase the participation of students in higher education, with a focus on increasing the access and success of students from disadvantaged backgrounds. It is unclear, however, what role the burgeoning private for-profit institutions will play in meeting the government's targets, and what incentives will be provided for them to increase the access and participation of students from disadvantaged groups. This paper analyses the key drivers of growth in private for-profit higher education in Australia, and discusses issues around quality and standards. It examines the strengths and limitations of the sector, and the extent to which it contributes to diversity, access and the participation of students from disadvantaged backgrounds. It argues that the sector needs clear government directions to improve levels of access, and new government policies to encourage public-private collaborations to help ensure sustainability. The paper also briefly touches on the need for a review into the current structure of Australia's higher education sector as a whole, and whether higher education would benefit from the formation of public community colleges with the explicit aim of widening access for disadvantaged student groups. Further, the paper suggests that encouraging such public-private collaboration may be beneficial to ensure access and participation of students from all walks of life, including disadvantaged groups. 相似文献
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Ashavaid T. F. Altaf A. K. Nair K. G. 《Indian journal of clinical biochemistry : IJCB》2000,15(1):11-16
Modification of platelet proteins by free radicals and glycation has been studied in the present work, as anin vitro model. The results of the two parameters, SDS-PAGE and carbonylation study are quite corroborative. We observed that the
inducers like ferrous sulphate, ascorbate (mainly in supraphysiological concentration) and glucose attack the protein in a
dose dependent manner, of which ferrous sulphate is most potent. Proteins from aged and degenerative conditions like malignancy
and diabetes mellitus have suffered greater damage than normal adult and foetal proteins. The individual life expectancy in
terms of biological versus chronological age may also be worked out from the individual stress level. 相似文献
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Tester F. Ashavaid Farah F. Eghlim Kavita K. Shalia Kappiareth G. Nair 《Indian journal of clinical biochemistry : IJCB》2003,18(2):106-110
Determination of plasma total homocysteine by high-pressure liquid chromatography (HPLC) usually requires reduction of protein
bound or free homocysteine-disulphides into thiols by a reducing agent and the liberated thiols are then derivatized by a
fluorescent marker. In this study we have standardized the HPLC method for homocysteine measurement using dithiothreitol (DTT)
as reductant.
The results of plasma total homocysteine values obtained by HPLC were compared with IMx method. The difference between the
two means was statistically insignificant [P=0.616847 (two tail)] Linear regression analysis showed strong correlation between
the two methods (r=0.983). Using this method we have analyzed 132 controls and 130 Coronary Heart Disease (CHD) patients for
plasma total homocysteine, wherein, the mean plasma total homocysteine levels were 10.51±8.36 and 11.51±10.06 μmol/L respectively.
Our research study suggests that DTT method is a simple and inexpensive assay for homocysteine determination in human plasma
for research application. 相似文献
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Ashavaid T. F. Shalia K. K. Nair K. G. Dalal J. J. 《Indian journal of clinical biochemistry : IJCB》2000,15(1):1-5
The levels of cytotoxic aldehydic products in different culinary oils, with or without thermal stress, (routine domestic or
commercial frying) were determined by thiobarbituric acid method. The results showed that (i) thiobarbituric acid reactivity
was much higher in edible oils rich in polyunsaturated fatty acids than those rich in saturated fatty acids or monounsaturated
fatty acids, even without thermal stress, (ii) the lipid peroxide levels were in proportion to the duration of thermal stress,
(iii) nature of the container used (steel, iron or teflon-coated) had no significant effect on the extent of lipid peroxidation
under identical conditions of thermal stress and (iv) thermally stressed oils collected from hotels and roadside caterers
contained higher levels of cytotoxic aldehydic products, when compared to oils thermally stressed under domestic frying conditions.
These results suggest that dietary ingestion of thermally or autoxidatively stressed polyunsaturated fatty acid rich culinary
oils is more harmful compared with those similarly treated oils rich in saturated fatty acids and monounsaturated fatty acids. 相似文献
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The purpose of this study was to modify and validate a new form of the College and University Classroom Environment Inventory
(CUCEI), and to then use it to compare students' actual and preferred perceptions of their classroom learning environments
at the senior secondary and teritary levels of education. The study also examined differences in perceptions according to
the student's gender. A sample of 504 students participated in the study. The reliabilities of the scales of the modified
CUCEI ranged from .73 to .94. When the two levels were compared, students at the higher education level had a less favourable
perception of their learning environment. Previous research was replicated in that females were found generally to perceive
their learning environments in a more positive way than did males and that all students generally preferred a more positive
learning environment in their classes. 相似文献
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Leticia I. RAMíREZ-CAVAZOS Charles JUNGHANNS Rakesh NAIR Diana L. CáRDENAS-CHáVEZ Carlos HERNáNDEZ-LUNA Spiros N. AGATHOS Roberto PARRA 《Journal of Zhejiang University. Science. B》2014,15(4):343-352
研究目的：优化获得血红密孔菌（P.sanguineus）的最佳培养基组成,提高耐热漆酶的产量。创新要点：获得了目前文献报道的最高水平的漆酶活力。研究方法：通过单因素试验研究了不同培养基（番茄汁、麦麸、麦芽提取物和葡萄糖细菌蛋白胨培养基）和不同组合诱导剂（大豆油、阿魏酸、没食子酸、二甲基苯胺、酸性蓝62和活性蓝19分别与硫酸铜组合诱导剂）对P.sanguineus产耐热漆酶的影响。在此基础上采用中心组合试验设计,进一步研究了番茄汁培养基结合硫酸铜和大豆油组合诱导剂对P.sanguineus产耐热漆酶的影响。利用SAS10.0和响应面分析方法对试验结果进行了统计分析和建立回归模型。重要结论：通过中心组合设计优化得出P.sanguineus产耐热漆酶的最优培养基条件：以36.8%番茄汁为培养基,以3 mmol/L硫酸铜和1%大豆油作为组合诱导剂。该条件下在10 L搅拌槽生物反应器中漆酶活力达到了143 000 IU/L（2,2＇-联氮双（3-乙基苯并噻唑啉-6-磺酸）为底物,pH值为3.0）。 相似文献