The neural correlates of working memory training in typically developing children     

Jonathan S. Jones  Anna-Lynne R. Adlam  Abdelmalek Benattayallah  Fraser N. Milton 《Child development》2022,93(3):815-830

Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed.  相似文献   

Refugees in Context: A Systemic,Intersectional Exploration of Discrimination in the United States     

Interiano-Shiverdecker  Claudia G.  Kondili  Elvita  Bazzi  Reyma 《International journal for the advancement of counseling》2022,44(2):263-282

International Journal for the Advancement of Counselling - The goal of this study was to examine how individual, community, and socio-political mechanisms of discrimination intersect, manifest, and...  相似文献   

A Symbiosis of Access: Proliferating STEM PhD Training in the U.S. from 1920–2010     

Fernandez  Frank  Baker  David P.  Fu  Yuan-Chih  Muñoz  Ismael G.  Ford  Karly Sarita 《Minerva》2021,59(1):79-98

Minerva - Over the course of the 20th century, unprecedented growth in scientific discovery was fueled by broad growth in the number of university-based scientists. During this period the American...  相似文献   

Modeling the Pathways to Self-Confidence for Graduate School in Computing     

Wofford  Annie M. 《Research in higher education》2021,62(3):359-391

Research in Higher Education - Given the significant need to increase and diversify graduate enrollments within computing fields, it is vital to understand what shapes students’ pathways to...  相似文献   

(B) CBQ CURRENTS—TOPICAL ESSAYS ABOUT CONTEMPORARY IDEAS     

Meta G. Carstarphen 《Communication Booknotes Quarterly》2018,49(1):3-4

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Does modality matter? A latent profile and transition analysis of sedentary behaviours among school-aged youth: The UP&DOWN study     

David Sánchez-Oliva  Rebecca M. Leech  Alberto Grao-Cruces  Irene Esteban-Cornejo  Carmen Padilla-Moledo  Oscar L. Veiga 《Journal of sports sciences》2020,38(9):1062-1069

ABSTRACT

The aims of this study were to identify profiles of sedentary behaviour (SB) patterns, based on leisure-time self-reported SB modalities (screen, educative, social, and relaxing) and to evaluate changes in these profiles over 2 years among Spanish youth aged 8–18 years. Latent profile analysis (LPA), a data-driven analytic approach, was used to identify groups of boys and girls (n = 1553; 48% girls; mean±SD age: 12.56 ± 2.49 y) with distinct SB profiles using the SB modalities (time/d) as input variables. Latent transition analysis, an extension of LPA that uses longitudinal data, was used to analyse 2-year changes in these profiles. At baseline, four and three SB profiles were found among boys (labelled: screen, educative, social, and relaxing) and girls (labelled: screen/social, educative, and relaxing), respectively. Overall, more girls (range: 48%-67%) had the same profile over time, than boys (40%-52%). Participants with a screen or relaxing SB profile at baseline were more likely to have an educative profile after 2 years. Youth with a social and an educative SB profile at baseline were more likely to transition to profiles characterized by higher screen and social SB, respectively. Using a novel and person-centered approach, this study identified gender-specific SB profiles that were moderately stable over time.  相似文献   

Could knee joint mechanics during the golf swing be contributing to chronic knee injuries in professional golfers?     

Howie Carson  Jim Richards  Simon G. S. Coleman 《Journal of sports sciences》2020,38(13):1575-1584

ABSTRACT

Full three-dimensional movements and external moments in golfers’ knees and the possible involvement in injuries have not been evaluated using motion capture at high sample frequencies. This study measured joint angles and external moments around the three anatomical axes in both knees of 10 professional golfers performing golf drives whilst standing on two force plates in a motion capture laboratory. Significant differences were found in the knee joint moments between the lead and trail limbs for the peak values and throughout all stages during the swing phase. A significantly higher net abduction moment impulse was seen in the trail limb compared with the lead limb (?0.518 vs. ?0.135 Nms.kg^?1), indicating greater loading over the whole swing, which could contribute to knee lateral compartment or anterior cruciate ligament injuries. A significant correlation (r = ?0.85) between clubhead speed at ball contact and maximum joint moment was found, with the largest correlations being found for joint moments at the top of the backswing event and at the end of the follow-through. Therefore, although knee moments can contribute to high clubhead speeds, the large moments and impulses suggest that they may also contribute to chronic knee injuries or exacerbate existing conditions.  相似文献   

Editorial     

B. Sury 《Resonance》2018,23(7):723-725

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Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)     

Fadhaa A. Ghafil  Bassim I. Mohammad  Hussain S. Al-Janabi  Najah R. Hadi  Hayder A. Al-Aubaidy 《Indian journal of clinical biochemistry : IJCB》2021,36(1):81

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.  相似文献   

The Evolution of U.S. Museums and Science Centers as Informal Learning Environments     

Renee M. Clary 《Science & Education》2018,27(3-4):371-377

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