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行政许可法的颁布对于保护公民、法人和其他组织的合法权益,维护公共利益和社会秩序,保障和监督行政机关有效实施行政管理,推动政府进一步转变职能,加强廉政建设,促进社会主义市场经济体制的完善具有十分重要的作用。  相似文献   
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Objective: To investigate the immunological function of a yeast expression system for thymosin α1(Tα1). Methods: A constructed Tα1 yeast expression system was used to investigate the immunological function of orally administered Tα1. Dried yeast containing three different concentration of Tα1 was fed to normal Balb/c mice and other Balb/c mice whose immunities were inhibited in advance by cyclophosphamide. Synthesized Tα1 peptide was used as positive control and dried yeast with empty plasmid was used as negative control. CD4 and CD8 levels were detected by flow cytometry assay. TNF-α IFN-γ IL-2, IL-6 and IL-10 levels were detected by liquid chip. Results: In normal Balb/c mice or immune inhibition Balb/c mice, CD8 levels were significantly increased. Especially in immune inhibition Balb/c mice, CD8 levels in synthesized Tα1 group (18.77%±4.72%),small dose group (13.48%±6.17%) and large dose group (22.74%±1.09%) were significantly higher than that in empty yeast control group (7.49%±2.14%). Conclusion: Orally administered Tα1 has its certain immunomodulatory function.  相似文献   
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晚清戏曲理论批评家梁廷枏主张戏曲负有歌颂盛世、教育风化、动荡之际有补于世的政教功能,主张戏曲有揭露现实的黑暗、抒发对现实不满的宣泄不平功能,同时,他认为词曲为小技,还有娱乐抒怀的作用。由于动荡时代的需要,传统儒家诗教影响下文人自觉的社会责任感,兼受经世之学思想的影响,梁廷枏的戏曲功能论以富国强民的爱国精神为旨归。  相似文献   
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高等学校预算执行机制是预算管理的一个重要组成部分,经过了“统一领导、集中管理”和“统一管理、一级核算、定额包干、结余留用”的强加性预算执行机制及参与性预算执行机制三个时期。近十年的预算执行实践,不同程度地反映出预算执行机制存在着滞后、较粗、过度松弛等现象。本文通过设立全程参与性预算机制、业绩考核、预算执行情况分析、推行预算管理科目等设想入手,从实际出发,坚持以人为本,运用科学发展观,不断完善单位预算执行机制。  相似文献   
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摘要:随着我国体育社团管理体制改革的不断深化,运用社会资本的能力对体育社团的健康发展至关重要。作为经济社会发展水平居于全国前列的直辖市,其体育社团在社会资本利用方面具有先天的优势,这对于全国体育社团社会资本的培育和利用具有典型的前瞻性意义。基于此,综合运用文献资料法、德尔菲法、问卷调查法等研究方法,从结构型社会资本、关系型社会资本与认知型社会资本3个维度对我国4个直辖市体育社团社会资本进行了现状分析。研究认为:在良好的国家社团政策环境下,直辖市体育社团社会资本的培育和利用呈现良好态势,但也存在一些尚待解决的问题,集中表现在体育社团社会资本的结构有待优化、质量有待提高、运作有待加强等方面。在此基础上,从体育社团的自我发展驱动、体育社团社会资本的特色培育、体育社团社会资本的有效运作等3个方面提出了不断完善我国体育社团社会资本的路径。为新形势下我国体育社团合理运用社会资本,增强自身造血能力提供参考。  相似文献   
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边区非物质文化遗产在都市化背景下。出现了横向边区聚落和纵向代际生成的文化现象,有必要对其进行横向与纵向一体化的研究,而地方性高等院校是非物质文化遗产保护工程中连接政府机构与社会力量的桥梁,它承担着四重任务:记录、保存、文化创新与经济转化。  相似文献   
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贾平凹在长篇新作《秦腔》中的清风街为我们提供了西部农村社会现实的一个范本。这里积淀着以“秦腔”为代表的深厚的农耕社会文化,却缺乏现代文化气息,人的素质十分低下,社会体制以人治为主,再加上资源奇缺,使农民陷入了令人堪忧的困境。  相似文献   
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Objective: To investigate the immunological function of a yeast expression system for thymosin α1 (Tα1). Methods: A constructed Tα1 yeast expression system was used to investigate the immunological function of orally administered Tα1. Dried yeast containing three different concentration of Tα1 was fed to normal Balb/c mice and other Balb/c mice whose immunities were inhibited in advance by cyclophosphamide. Synthesized Tα1 peptide was used as positive control and dried yeast with empty plasmid was used as negative control. CD4+ and CD8+ levels were detected by flow cytometry assay. TNF-α, IFN-γ, IL-2, IL-6 and IL-10 levels were detected by liquid chip. Results: In normal Balb/c mice or immune inhibition Balb/c mice, CD8+ levels were significantly increased. Especially in immune inhibition Balb/c mice, CD8+ levels in synthesized Tα1 group (18.77%±4.72%), small dose group (13.48%±6.17%) and large dose group (22.74%±1.09%) were significantly higher than that in empty yeast control group (7.49%±2.14%). Conclusion: Orally administered Tα1 has its certain immunomodulatory function. Project (No. 2003C13015) supported by the Key Project from Science and Technology Department of Zhejiang Province, China  相似文献   
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Immunomodulatory function of orally administered thymosin α1   总被引:1,自引:0,他引:1  
INTRODUCTION The thymus is a vital immune organ and plays a very important role in the development and mainte- nance of the lymph system. The extract of animal thymus has been used in clinical practice as an ad- junct treatment in patients with carcinoma, viral in- fection and immunodeficiency, but the extract con- taining miscellaneous animal proteins may easily lead to allergy in patients. Thymosin α1 (Tα1) is the most potent ingredient in thymosin and the biological ac- tivity of pur…  相似文献   
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贾平凹在长篇新作<秦腔>中的清风街为我们提供了西部农村社会现实的一个范本.这里积淀着以"秦腔"为代表的深厚的农耕社会文化,却缺乏现代文化气息,人的素质十分低下,社会体制以人治为主,再加上资源奇缺,使农民陷入了令人堪忧的困境.  相似文献   
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