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1.
Luigi M Castello Sophie Negro Francesca Santi Isabella Zanotti Matteo Vidali Marco Bagnati Giorgio Bellomo Gian Carlo Avanzi 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(3):380-384
Introduction:
Two Italian adults arrived at the Emergency Department referring diarrhea, nausea and vomiting for 4 days; weakness, fatigue and visual hallucinations were also complained of. Patients reported the ingestion of some leaves of a plant, which they supposed to be “donkey ears”, a week before. Physical examination showed hypotension and bradycardia and ECG examination disclosed sinus rhythm and repolarization abnormalities (scooping of the ST-T complex) in both patients and a 2:1 AV block in the man.Materials and methods:
Digoxin concentration was evaluated twice for each patient (at the admission and after 4 hours) by the automated immunoassay system ADVIA Centaur®. Digitoxin concentration was evaluated by liquid chromatography-mass spectrometry (LC-MS/MS).Results:
Despite clinical picture was suggestive of digitalis intoxication, digoxin levels were undetectable. Due to the more severe clinical picture, the male patient was treated with anti-digoxin antibodies (Digifab®) achieving a good clinical improvement and remission of the AV block within two hours. Initial diagnosis was confirmed by LC-MS/MS showing high digitoxin concentrations, but digoxin was undetectable. Patients remained stable and 48 hours later were discharged from the hospital.Conclusion:
Whereas digoxin determination frequently relies on monoclonal antibodies which do not cross-react to digitoxin, polyclonal antibodies constituting Digifab® recognize a large spectrum of cardiac glycosides, including digitoxin. This report emphasizes the primary role of the clinical approach to patients in the emergency setting and how an active communication and a continuous sharing of professional experiences between Laboratory and Clinicians ensure an early and correct diagnosis. 相似文献2.
3.
石蔚 《河北北方学院学报(医学版)》2002,19(6):26-27
目的 :探讨乙酰胺肌注治疗儿童氟乙酰胺中毒的疗效与安全性。方法 :对收治的氟乙酰胺中毒儿童以乙酰胺肌注治疗 ,剂量为 10 0mg/kg .d ,作临床分析。 结果 :全部病例效果良好 ,无一例遗留后遗症。结论 :对有机氟类灭鼠药中毒早期使用肌注乙酰胺治疗 ,疗效较好 ,安全性好。 相似文献
4.
Gizem Karaali 《PRIMUS》2019,29(3-4):312-327
AbstractWe provide context and motivation for an instructor to use real-life examples in the calculus classroom. To this end we describe two specific project ideas, one related to the devastating impact of methylmercury fungicide in a grain seed supply and the other to a catastrophic methane leak. By using calculus in contexts that have social justice implications, we hope to empower students to reason for themselves, to use mathematics as a powerful tool to deepen their understanding of the world, and ultimately, to effectively confront the challenges society faces. 相似文献
5.
AdHoe网络有其自身优于其他网络的特点,但是这些特点不可避免的导致了它抵抗攻击的脆弱性。故安全性的研究成为AdHoe网络发展迫切解决的问题。在AdHoe网络中网络威胁和急待解决的问题,从网络的每层即网络应用层、传输层、网络层、数据链路层、物理层来分析关注AdHoc网络的安全性问题,给出每层中可能出现的安全威胁,以及对安全问题给出一定的解决方案。 相似文献
6.
缪小莉 《泰州职业技术学院学报》2010,10(3):34-35,59
目的观察血必净注射液在治疗急性有机磷农药中毒时的疗效。方法将82例急性有机磷农药中毒患者随机分为血必净治疗组（40例）与对照组（42例）,在正规使用阿托品及胆碱酯酶复能剂治疗的基础上,治疗组加用血必净100ml静脉点滴,每天一次,共3天,50ml静脉点滴,每天一次,共4天,总疗程一周。观察治疗过程中两组间全血胆碱酯酶及C反应蛋白差别,统计平均住院时间及死亡率。结果治疗前后,血必净治疗组及对照组的全血胆碱酯酶均有恢复,且治疗组较对照组恢复速度快（P〈O．05）。在C反应蛋白水平治疗后第3、4天数值较前均有所改善（P〈0．05）,治疗组改善更著（P〈O．05）。治疗组平均住院时间明显少于对照组（P〈O．05）。结论血必净注射液能有效促进血胆碱酯酶恢复,较好调控机体炎症反应过程,改善SIRS症状,缩短住院时间,取得满意的疗效。 相似文献
7.
Qin Zhang Wei-zhen Wu Yuan-qiang Lu Jie-zan Wang An-dong Shang Feng Yao Yan Chen 《Journal of Zhejiang University. Science. B》2012,13(5):413-418
Objective
To report on three patients with paraquat (PQ) intoxication surviving after combined therapy with hemoperfusion (HP), cyclophosphamide (CTX), and glucocorticoid. 相似文献8.
为了研究急性铅中毒对小鼠睾丸病理变化的影响,通过对小鼠饲喂含有醋酸铅的去离子水建立铅负荷小鼠模型.处理10 d后取材,分析体质量、睾丸指数和睾丸病理剖检变化.结果显示：与对照组相比,铅中毒组小鼠体质量无明显变化,睾丸指数降低,且差异显著（P＜0.05）;小鼠睾丸中支持细胞、生精细胞和间质细胞数量减少.铅对小鼠睾丸具有显著损害作用,从而影响小鼠的生殖健康. 相似文献
9.
寇瑾 《中国教育研究与创新》2005,2(11):33-35
治理“铅魔”危害，防止儿童铅中毒，这不仅仅是医学问题，也是一个家庭问题、社会问题，需要全社会高度重视，积极参与。 相似文献
10.
碳酸氢钠对人体运动能力的影响 总被引：2，自引：0，他引：2
通过对三种不同供能形式为主的运动项目运动员服用碳酸氢销后对运动成绩和某些生理生化指标的影响方面的研究进行综述和分析,揭示了服用碳酸氢钠诱导碱中毒对运动能力影响的机制。证实了口服一定剂量的碳酸氢钢有助于提高机体以乳酸能系统供能为主的运动项目的成绩。 相似文献