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Dietary spice components ofCurcuma longa andAbroma augusta have been screened for their protective effect against reactive oxygen species induced lipid peroxidation. They have been
found to be efficient antioxidant when administered in combination. The purpose of the study was to investigate the effect
of oral administration (300mg/Kg) of the aqueous extract of turmeric whose active ingredient isCurcumin andAbromine powder as a hypoglycemic agent mixed with diet. The effect of this aqueous extract on blood glucose, lipid peroxidation (LPO)
and the antioxidant defense system in rat tissues like liver, lung, kidney and brain was studied for 8 weeks in streptozotocin
induced diabetic rats. The administration of an aqueous extract of turmeric and abromine powder resulted in a significant
reduction in blood glucose and an increase in total haemoglobin. The aqueous extract also resulted in decreased free radical
formation in the tissues studied.
The decrease in thiobarbituric acid reactive substances (TBARS) and increase in reduced glutathione (GSH), superoxide dismutase
(SOD) and catalase (CAT) clearly showed the antioxidant property of the mixture. It is suggested that these changes initially
counteract the oxidative stress in diabetes however, a gradual decrease in the antioxidative process may be one of the factors
which results in chronic diabetes. These results indicate that the mixture of the two plants have shown antidiabetic activity
and also reduced oxidative stress in diabetes. A combination ofAbroma augusta and Curcuma longa also restored the other general parameters in diabetic animals. The results were statistically analyzed and indicated that
combination of herbal extracts showed better efficacy as compared to individual herbal plant extracts used. 相似文献
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Biswajit Saha 《Indian journal of clinical biochemistry : IJCB》2006,21(2):67-71
During routine screening, some otherwise healthy individuals who showed remarkably lower post prandial (at 2 hour) plasma
glucose without any symptom were subjected to extended glucose tolerance test and a few of them to extended post meal tolerance
test as well. It was observed that post prandial (at 2 hour) plasma glucose after glucose administration was significantly
lower than the fasting level (p<0.05−p<0.001). However, post prandial plasma glucose at 2 hour after their usual meal exhibited
a significantly higher level than the fasting and post glucose level (p<0.05−p<0.001). Glucose appears to be a stronger agent
than the more natural mixed meal in these individuals in causing post prandial lowering of plasma glucose. Hence, these individuals
are to be evaluated with their usual meals before considering further investigations. Like upper limit, there is the need
to have a consensus lower limit of reference interval of blood glucose level. 相似文献
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老年糖尿病并发低血糖误诊原因分析及诊治 总被引：4，自引：0，他引：4
林荣 《河北北方学院学报(医学版)》2005,22(1):76-77
目的:探讨老年糖尿病并发低血糖的临床特点、误诊原因及诊断治疗.方法:回顾性分析我院收治的老年糖尿病并发低血糖病人32例.结果:院内、外误诊18例(56%).结论:通过了解老年糖尿病的生理、临床特点,提高对并发低血糖的警惕,及时检测血糖,同时建议临床医师指导病人合理用药,加强对本病的预防. 相似文献
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运动负荷试验是评定人体工作能力、确定心血管机能状态常用的实验方法。其实验时间短,运动量较小,一般不易发生低血糖休克。本例受试者空腹时间过长,在逐级递增负荷运动试验后恢复期发生低血糖休克。在运动负荷试验时发生低血糖休克,须与其它原因所致的休克,尤其是心源性休克相鉴别。及时静脉注射高渗糖,可使病人迅速痊愈。长时间空腹状态应作为运动负荷试验禁忌症。 相似文献
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许瑞凌 《襄樊职业技术学院学报》2014,(2):49-50
目的 分析门诊输液病人发生低血糖反应的原因,寻求预防方法.方法 对襄阳职业技术学院附属医院2012年1至12月门诊输液出现低血糖反应的病人进行原因分析.结果 出现低血糖反应者多为幼儿、老年人和老年糖尿病人,输液溶媒为盐水.结论 门诊输液病人出现低血糖的原因多样,尤以幼儿、老年及老年糖尿病人多见,早预防可防止其发生. 相似文献
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邱俊英 《孝感职业技术学院学报》2008,11(2):107-108
目的：探讨饮酒后低血糖昏迷的发生机制及诊疗方法。方法：选择我院急诊酒精中毒患者16例,根据其入院时临床表现及低血糖程度,给予高糖及纳洛酮静滴,观察患者治疗后的症状及血糖改善的变化。结果：经过2h治疗后所有患者症状均有明显的改善,昏迷患者意识逐渐恢复,心悸,震颤,出汗等症状好转,复查血糖在4．4～6．2mmol／L后出院。结论：空腹及有肝病史患者在大量饮酒后易出现低血糖表现,发病机制是酒精在肝脏内代谢,可抑制糖异生引起低血糖;此外,饮酒后乙醇可刺激胰岛素分泌增加导致低血糖发生。同时,需要注意与醉酒症状及脑血管病相鉴别。 相似文献
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