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目的:探讨去甲肾上腺素对人THP-1细胞CD137、IL-6及HMGB1表达的影响.方法:加入101μmol/L的去甲肾上腺素处理THP-1细胞1小时.运用逆转录多聚酶链反应检测其CD137、IL-6及HMGB1mRNA的表达.结果:10μmol/L的去甲肾上腺素能上调THP-1细胞CD137及IL-6mRNA的表达,与对照组比较差异有显著性(P<0.01);但对HMGB1mRNA的表达没有影响.结论:去甲肾上腺素上调THP-1细胞CD137及IL-6mRNA水平. 相似文献
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速滑运动员心理发挥状态与儿茶酚胺排除量和状态焦虑关系的探讨 总被引：1，自引：0，他引：1
以尿内儿茶酚胺排出量和状态焦虑为观察指标,在运动员参加重大比赛期间进行了不同时段检测。结果表明:比赛发挥好的运动员在赛前0.5~2h段表现出较高心理激活水平;而比赛发挥差的运动员则表现相反,并且还有在赛前和比赛后儿茶酚胺排出量明显增加及高焦虑的特点。 相似文献
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Niels Holmqvist Niels H. Secher Kåre Sander‐Jensen Ulrich Knigge J⊘rgen Warberg Thue W. Schwartz 《Journal of sports sciences》2013,31(2):123-128
Exhaustive exercise is associated with a persistent sensation of weakness and sometimes nausea suggesting abdominal vagal activity. We measured plasma indices of sympathoadrenal (adrenaline, noradrenaline, dopamine) and vagal (pancreatic polypeptide) activity before, during and after submaximal and maximal exercise in healthy young subjects. Plasma adrenaline, noradrenaline and dopamine increased to 8.5 (range 7.4–40.5), 48.0 (32.3–100.5) and 1.8 (1.2–6.6) nmol l–1 respectively (n = 5), during maximal exercise and decreased towards control values within 15 min of rest. Pancreatic polypeptide (n = 10) increased only during maximal exercise and reached its highest value, 48 (21–145) pmol l–1, after exertion. The results conform to an increase in sympathetic activity during exercise and a persistent vagal activity after intense exercise which could contribute to the sensation of weakness. 相似文献
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