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Hepatocellular carcinoma (HCC) is one of the commonest tumors worldwide. The treatment of HCC is vital for disease diagnosis and prognosis, as the liver is the most important organ controlling metabolic functions. Now-a-days, western folklore medicines are largely dependent on the phyto compounds which are highly effective in therapy and with low side effects. Luteolin is a flavonoid (3,4,5,7-Tetrahydro flavones) possess anti-inflammatory, anticancer and anti allergic property. The present study evaluates the efficacy of luteolin against N-nitrosodiethylamine (DEN) induced HCC in albino rats. In the highlight of the above, luteolin was evaluated for its efficacy against DEN induced HCC in male Wistar albino rats. The Biochemical parameters such as tissue damaging enzymes viz., AST, ALP, LDH and γ-GT, enzymatic antioxidants viz., SOD, CAT, GSH and GPx and histopathological changes have been estimated. The tissue damaging enzymes were found to be high in DEN alone treated group whereas the enzymatic antioxidants decreased destructively. Severe lesions and cirrhosis were observed in the toxin (DEN alone) treated group. The luteolin treated DEN group altered the tissue damaging enzymes and the enzymatic antioxidants. The damaged lesion in the histoarchitecture of DEN treated rat liver was almost completely restored. Finally this study strongly demonstrates that luteolin has potent curative property against HCC in albino rats. 相似文献
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施春华 《泰州职业技术学院学报》2005,5(5):80-82
人格品质在个人生活中占有极其重要的地位.大学生良好品格的形成不仅关系到个人的建功立业,更与祖国实现社会主义现代化的伟大事业密切相关.高校两课是培养青年大学生的人格品质的重要阵地.在两课教学过程中,突出邓小平人格品质的概述,发挥榜样教育的作用,这会对大学生的品质形成产生积极影响. 相似文献
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李玲 《商丘职业技术学院学报》2012,(3):8-9
在新的历史时期,邓小平思想政治教育理论适应时代要求和广大人民群众的迫切需要,丰富和发展了马克思关于思想政治工作的思想,是指导我们在思想政治教育领域开拓创新的强大思想武器,是社会主义思想政治工作发展史上的一个新的里程碑。 相似文献
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