排序方式： 共有12条查询结果，搜索用时 15 毫秒
1.
目的：研究中药与一氧化氮（NO）的腹膜淋巴孔调控，探讨中药复方的消腹水机理，方法：通过扫描电镜观察和计算机图像处理定量分析，测定腹膜淋巴孔孔径、面积和开放密度，同时测定尿钠浓度。结果：（1）中药组腹膜淋巴孔孔径，面积和开放密度均增大，尿钠排出量显著增多（P＜0．01）；（2）NO供体硝普钠组腹膜淋巴孔孔径，面积和开放密度均增加（P＜0．01或P＜0．05）；（3）在给中药时，又给NO合酶抑制剂L－硝基精氨酸，腹膜淋巴孔孔径，面积及开放密度均减小（P＜0．01）。结论：本中药复方有较好的调控淋巴孔促尿钠离子排出的作用，结果提示，中药可能是通过升高内源NO浓度，舒张腹膜淋巴孔达到消腹水作用。 相似文献
2.
目的:观察过度训练对大鼠腹膜巨噬细胞吞噬功能的影响及胰岛素样生长因子1(IGF-1)和机械生长因子(MGF)在其中所起的作用.方法:8周龄健康雄性Wistar大鼠16只,随机分为安静对照组(control)和过度训练组(overtraining).过度训练组进行11周递增负荷跑台训练.最后1次训练后36 h,记录体重变化并测定血液中血红蛋白和睾酮含量.断头处死大鼠并分离纯化腹膜巨噬细胞,中性红法测定巨噬细胞吞噬功能,荧光定量PCR技术测定IGF-1和MGF基因表达.离体状态下用不同浓度的IGF-1或MGF与巨噬细胞孵肓2h,观察IGF-1和MGF对巨噬细胞吞噬功能的影响.结果:与安静对照组相比,过度训练组大鼠体重、血红蛋白和睾酮含量均显著降低,分别下降了约19.3％(P＜0.01)、13.5％(P＜0.01)、55.3％ (P＜0.01).过度训练组巨噬细胞摄取中性红能力显著低于安静对照组,下降约27％(P＜0.05);过度训练组巨噬细胞IGF-1 mRNA水平约为安静对照组的21倍(P＜0.01),MGF mRNA水平约为安静对照组的92倍(P＜0.01);IGF-1对巨噬细胞吞噬功能无显著影响,各浓度组与未加药组相比均无显著性差异(P＞0.05); MGF呈浓度依赖性的抑制巨噬细胞吞噬功能,与未加药组相比,10 ng/ml、50 ng/ml组有显著性差异(P＜0.05),l00 ng/ml、200 ng/ml组有极显著性差异(P＜0.0l),各浓度组间比较无显著性差异(P＞0.05).结论:过度训练抑制巨噬细胞吞噬功能;过度训练诱导产生的MGF可能在过度训练抑制巨噬细胞吞噬功能中发挥关键作用. 相似文献
3.
4.
5.
Geoffroy P.J.C. Noël 《Anatomical sciences education》2013,6(1):67-71
Anatomy teaching is seeing a decline in both lecture and laboratory hours across many medical schools in North America. New strategies are therefore needed to not only make anatomy teaching more clinically integrated, but also to implement new interactive teaching techniques to help students more efficiently grasp the complex organization of the human body. Among the difficult anatomical concepts that students struggle to understand, the anatomy of the peritoneal cavity with its complex projections of peritoneum could benefit strongly from new learning aids. In this report, an innovative teaching tool is presented to engage students during both lecture and laboratory, and help them build three‐dimensional (3D) mental maps of peritoneal cavity. The model consists of a patchwork of mesenteries and gut made from colored cloth stitched together onto a T‐shirt to denote the origin and outflow of each peritoneum projection. As the lecturer wears the life‐size model, the students can appreciate the 3D organization of the peritoneal cavity on a living body. In addition, the T‐shirt model can be used in parallel with dissection to ensure a strong reinforcement of the spatial understanding of the peritoneal cavity. Anat Sci Educ. © 2012 American Association of Anatomists. 相似文献
6.
本文对近五年来经手术证实的217例十二指肠溃疡穿孔,行术中腹腔灌洗(IOPL)治疗情况进行临床分析。灌洗液通常采用生理盐水或林格氏液,总量为1000～2000ml。其中选择30例,应用每1000ml 灌洗液中加入0.5%灭滴灵100ml 和庆大霉索24万 u 进行灌洗;术后与对照组比较观察并发症减少,并降低残死亡率。 相似文献
7.
Lara Milevoj Kopcinovic Jelena Culej 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2014,24(1):123-137
The pathological accumulation of serous fluids in the pleural, peritoneal and pericardial space occurs in a variety of conditions. Since patient management depends on right and timely diagnosis, biochemical analysis of extravascular body fluids is considered a valuable tool in the patient management process.The biochemical evaluation of serous fluids includes the determination of gross appearance, differentiation of transudative from exudative effusions and additional specific biochemical testing to assess the effusion etiology. This article summarized data from the most relevant literature concerning practice with special emphasis on usefulness of biochemical tests used for the investigation of pleural, peritoneal and pericardial effusions. Additionally, preanalytical issues concerning serous fluid analysis were addressed and recommendations concerning acceptable analytical practice in serous fluid analysis were presented. 相似文献
8.
石耳多糖对小鼠免疫功能影响的初步研究 总被引：1，自引：0，他引：1
通过酸、碱、水三种方法提取石耳子实体多糖,分别腹腔注射(200mg/kg)免疫小鼠,观察三种提取物对正常小鼠免疫功能的影响。结果表明:水提法多糖得率最高(4.3%)。三种提取物均能显著提高(p<0.01)小鼠腹腔巨噬细胞吞噬能力;并使小鼠脾脏重量明显增加,而胸腺重量显著减轻。 相似文献
9.
四君子汤对小鼠抗疲劳耐缺氧作用的研究 总被引：1，自引：0，他引：1
观察四君子汤对小鼠抗疲劳、耐缺氧能力的影响,并探讨其作用机理.方法:用水提醇沉法制得四君子汤.取小鼠160只,随机分成Ⅰ、Ⅱ、Ⅲ、Ⅳ四组,Ⅰ和Ⅲ组灌胃、Ⅱ和Ⅳ组腹腔注射四君子汤.各处理组给药浓度分别为0.5g/mL、1.0g/mL、1.5g/mL,给药量均为0.2mL/10g,对照组给予等量生理盐水.连续6天,在最后一次给药30min后,进行负重游泳及耐缺氧试验,测定小鼠的存活时间.结果:在耐缺氧试验中,腹腔注射高剂量(1.5g/mL)四君子汤作用效果明显(P＜0.05),其他各处理组小鼠在不同的抗应激试验中生存时间均比对照组延长,但差异不显著(P＞0.05).结论:灌胃和腹腔注射四君子汤水提醇沉液对小鼠均有一定的抗疲劳和耐缺氧作用. 相似文献
10.
氧氟沙星、糜蛋白酶腹腔灌注对术后腹腔粘连预防作用的实验研究 总被引：2，自引：0，他引：2
目的探讨氧氟沙星、糜蛋白酶腹腔灌注对污染手术后腹腔粘连的预防作用．方法家兔36只,随机分成模型组、预防组及对照组．制成污染手术后腹腔粘连模型,预防组腹腔灌注氧氟沙星12mg／kg,糜蛋白酶400u／kg,并以右旋糖研对照．结果预防组腹腔粘连程度较模型组、对照组显著减轻（P＜0．01）结论氧氟炒星、糜蛋白酶腹腔灌注对污染手术后腹腔粘连具有预防作用． 相似文献