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Kang CHEN Ye MAO Shao-hua LIU Qiong WU Qing-zhi LUO Wen-qi PAN Qi JIN Ning ZHANG Tian-you LING Ying CHEN Gang GU Wei-feng SHEN Li-qun WU 《Journal of Zhejiang University. Science. B》2014,15(6):507-514
Objective
We are aimed to investigate whether right ventricular mid-septal pacing (RVMSP) is superior to conventional right ventricular apical pacing (RVAP) in improving clinical functional capacity and left ventricular ejection fraction (LVEF) for patients with high-degree atrio-ventricular block and moderately depressed left ventricle (LV) function.Methods
Ninety-two patients with high-degree atrio-ventricular block and moderately reduced LVEF (ranging from 35% to 50%) were randomly allocated to RVMSP (n=45) and RVAP (n=47). New York Heart Association (NYHA) functional class, echocardiographic LVEF, and distance during a 6-min walk test (6MWT) were determined at 18 months after pacemaker implantation. Serum levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) were measured using an enzyme-linked immunosorbent assay (ELISA) kit.Results
Compared with baseline, NYHA functional class remained unchanged at 18 months, distance during 6MWT (485 m vs. 517 m) and LVEF (36.7% vs. 41.8%) were increased, but BNP levels were reduced (2352 pg/ml vs. 710 pg/ml) in the RVMSP group compared with those in the RVAP group, especially in patients with LVEF 35%–40% (for all comparisons, P<0.05). However, clinical function capacity and LV function measurements were not significantly changed in patients with RVAP, despite the pacing measurements being similar in both groups, such as R-wave amplitude and capture threshold.Conclusions
RVMSP provides a better clinical utility, compared with RVAP, in patients with high-degree atrioventricular block and moderately depressed LV function whose LVEF levels ranged from 35% to 40%. 相似文献2.
计算机辅助教学(CAI)在盲校英语教学中的运用顺应了教育改革和发展的大趋势,符合"缺陷补偿"的教学原则,适应视障学生身心发展的需要.利用CAI可以增强视障学生英语词汇的记忆效果,为他们创设良好的语言情境,帮助他们掌握知识重点,还能发挥其主体作用,激发其学习兴趣,并及时反馈教学效果,全面提高教学效率. 相似文献
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《运动与健康科学(英文)》2014,3(1):43-51
BackgroundRegular exercise is beneficial for adults with cardiovascular disease (CVD) and CVD risk factors. Tai Ji Quan is popular among older adults and may offer additional exercise options. The present article aims to review the scientific literature published within the past decade on Tai Ji Quan as an exercise modality to prevent and manage CVD.MethodsAn electronic literature search of four databases (PubMed, CINAHL, PsycINFO, and AMED) was conducted from April 2003 through March 2013. Studies that examined Tai Ji Quan, were published in English, and specified a target study population of participants with a known CVD condition (e.g., coronary artery disease, chronic heart failure, or stroke) or studies conducted among participants with a CVD risk factor (e.g., hypertension, dyslipidemia, or impaired glucose metabolism) were included.ResultsA total of 20 studies met the inclusion criteria: 11 randomized clinical trials, seven quasi-experimental studies and two cross-sectional studies. The effect of Tai Ji Quan was examined on more than 20 different study variables among persons with coronary artery disease (n = 5 studies), chronic heart failure (n = 5 studies), stroke (n = 4 studies), and CVD risk factors (n = 6 studies). These studies were conducted primarily in Asia (n = 9, 45%) or the United States (n = 8, 40%). Overall, participants enrolled in Tai Ji Quan had better outcomes, though mixed results were reported.ConclusionCollectively, these studies indicate that Tai Ji Quan is a safe form of exercise to prevent and manage CVD. Further research is needed with more rigorous study designs, larger sample sizes, adequate Tai Ji Quan exercise doses, and carefully chosen outcome measures that assess the mechanisms as well as the effects of Tai Ji Quan, before widespread recommendations can be made. 相似文献
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Hermundur Sigmundsson Marianne StØlan Rostoft 《Scandinavian Journal of Educational Research》2013,57(4):451-459
This study set out to explore motor competence in 4-year-old children. This age group has not been previously tested in Norway. Ninety-one 4-year-old children from ten nursery schools were tested using the Movement ABC test. The most striking finding was that only one out of 91 children would be classified as clumsy within the fifth percentile of the USA norms, with seven children being 'borderline'. The study also showed that out of the eight children failing in the motor impaired and borderline groups, seven were boys. Clear sex differences were also apparent in the development of motor skills. On the total scores and in the two of three sections (manual dexterity and balance) boys were significantly worse than girls. There were no significant differences between the sexes with respect to ball skills competence. 相似文献
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Arvind Kumar Poornima Tewari Sibasis S. Sahoo Arvind Kumar Srivastava 《Indian journal of clinical biochemistry : IJCB》2005,20(2):10-17
A total of 172 first degree relatives (FDRs) and 178 controls were included in this study. All the cases and controls were
subjected to various anthropometric measurements, fasting and postprandial glucose estimation, fasting insulin measurement
and fasting lipid profile. Results revealed the prevalence of Impaired Fasting Glucose (IFG) (cases 37% Vs controls 11.6%),
Impaired Glucose Tolerance (IGT) (cases 34.3% Vs controls 11.2%) and diabetes (cases 11.05% controls 3.37%) was significantly
higher in first degree relatives. Insulin resistance was measured using various methods, which included fasting plasma insulin
(FPI), Homeostasis Model Assessment for Insulin Resistance (HOMAIR), insulin sensitivity index (ISI) (Mffm/l). Prevalence of insulin resistance (Insulin Resistance) as observed comparing FPI
and HOMAIR in cases and controls was 43.6% and 11.24% (P=0.005) and 37.8% and 12.47% (P=0.000) respectively. Prevalence of IR (Insulin
Resistance) observed in cases having Normal Glucose Tolerance (NGT), Impaired Fasting Glucose (IFG), Impaired Glucose Tolerance
(IGT) and diabetes mellitus measuring FPI Vs HOMAIR was 37.5% vs 30.2%, 45% vs 40%, 38.98% vs 37.28% and 36.84% vs 31.57% as accordingly. However, ISI (Mffm/l) was not found
to be a promising index for IR due to its poor specificity. Though HOMA is taken as gold standard for measurement of IR globally,
our study observed fasting plasma insulin representing high sensitivity (89.7%) and specificity (93.3%) as compared to HOMA.
Thus FPI had emerged in this work as a simple and reliable test for diagnosing insulin resistance across the population susceptible
to develop diabetes including FDRs. 相似文献
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张杨 《乐山师范学院学报》2013,28(5):133-137
通过作文资料收集法,对7-9年级聋生及普生冲突解决策略的运用情况进行了调查,比较了7-9年级聋生和普校学生同伴冲突解决策略特点的差异及差异程度。研究结果表明:7-9年级聋生与普通学生应对冲突策略存在差异,并且表现出年级、性别特征。总体来看普生解决冲突更具建设性,而聋生依靠第三者介入较多。 相似文献
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从盲人数字图书馆项目管理的角度,对系统的建设和设计背景、功能需求以及技术架构等方面进行分析和论述,并对盲人数字图书馆的相关技术内容进行必要的整理和归纳。 相似文献
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The effect of communication anxiety upon signing effectiveness among the profoundly hearing‐impaired
Melanie Booth‐Butterfield Debra Heare Steve Booth‐Butterfield 《Communication quarterly》2013,61(3):241-250
Anxiety influences and interferes with the production of messages, yet findings linking trait anxiety with communication gestures and movement have been inconsistent and weak. This may be because most studies observe the communicative movements which complement the message rather than movements which constitute the primary message. This study examined the influence of predisposi‐tional anxiety on gestures when they are the central channel of communication— the signing behavior of deaf students. Anxiety was significantly related to signing in that more predispositionally anxious students' signs were less dear, slower, smaller, less intense, were more incomplete, and generally less effective compared to less anxious students. However compared to the general population, deaf students were not found to be more fearful of communication overall. 相似文献
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