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对非英语专业高职生的英语语用能力进行分年级的横向和纵向量化研究,结果显示,我国非英语专业高职生在一定程度上存在着英语语用能力石化现象。造成语用能力石化现象的主要原因是母语干扰与目的语文化知识的匮乏等因素。对此,笔者从高职英语教学的角度提出了应对非英语专业高职生英语语用能力石化现象的一些设想。 相似文献
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摘要：目的：分析中国不同人群中葡萄糖转运蛋白4基因多态性分布特征，寻找与运动能力关联的多态位点，作为中长距离游泳项目选材用基因标记。方法：选择120名中国优秀游泳运动员，采用飞行时间质谱（TOF-MS）解析葡萄糖转运蛋白4（GLUT4）rs5418位点；对照组为206名普通大学在校学生，多态位点的分析采用常规方法PCR-RFLP。结果：1）运动员组和对照组的基因型分布频率都符合Hardy-Weinbery平衡；2）实验组rs5418的基因型分布频率与对照组相比有显著性差异（χ2=6.338，df=2，P=0.042），携带AA纯合子型的游泳运动员显著性高于对照组；3）rs5418等位基因分布，2组具有显著性差异（χ2=6.171，df=1，P=0.008），对照组中A型等位基因极其低于运动员组；4）AA纯合型与AG+GG复合基因型分布，实验组和对照组有显著性差异（χ2=5.877；df=1，P=0.015）。结论：GLUT4基因rs5418多态位点与优秀中长距离游泳运动能力关联，可以作为该项目选材用分子标记。 相似文献
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BackgroundA single nucleotide polymorphism (SNP), rs53576, of the oxytocin receptor gene (OXTR) has been associated with fundamental aspects of social processes and behaviors. Compared to A carriers, GG individuals have enhanced social competencies and tend to elicit more positive responses from social partners. However, the G allele of the OXTR rs53576 has also been associated with greater social sensitivity.ObjectiveThe current study examined the unique influence of emotional childhood abuse on positive and negative aspects of different types of social relationships (e.g., family, spouse/partner, and friends) in midlife and whether genetic variations of OXTR rs53576 moderated these associations.Participants and Setting: A total of 614 participants in midlife (aged 40–65), recruited for a large-scale study of Phoenix metropolitan residents (AS U Live Project), answered self-report questionnaires and provided blood samples for DNA genotyping.MethodsHierarchical multiple regression analyses tested whether emotional childhood abuse predicted social support and strain for each relationship type and whether these potential linkages differed by OXTR genotype (GG versus AA/AG).ResultsOverall, individuals with a history of emotional childhood abuse had less supportive and more strained relationships in midlife. For supportive family relationships, the effect of emotional childhood abuse was moderated by OXTR rs53576 (p < .001). Under conditions of experiencing more emotional abuse in childhood, GG individuals had more supportive family relationships in midlife compared to A carriers.ConclusionsOverall, genetic variations of OXTR rs53576 may be an important candidate in understanding the development of social functioning within the context of emotional childhood abuse. 相似文献
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Dalya Sh. Al-owaidi Moaed E. Algazally Alaa Sadeq Alawaad 《Indian journal of clinical biochemistry : IJCB》2021,36(3):304
This case–control study is aimed to evaluate serum concentration of Cyclin-Dependent Kinase 6 (CDK6) and the genetic association between rs2237572 CDK6 gene and breast cancer (BC) in Iraq. To attain this goal, 80 patients with BC as cases and 80 healthy individuals as controls were included. Further, BC patients were sorted according to the molecular classification into four subtypes of Luminal A, Luminal B, Her2/neu enriched and TPN. Serum concentration of CDK6 enzyme, allelic and genotypic frequencies of rs2237572 CDK6, and the occurrence of BC phenotype and its subtypes in the studied population were investigated. ELISA technique was used to perform the biochemical testing, while the molecular analysis was achieved by real-time PCR, high resolution melting analysis, conventional PCR, as well as sequencing analysis. The results revealed no significant difference in serum concentration of CDK6 enzyme between patients and healthy controls (p > 0.05). Also, no significant differences were shown between BC patients subtypes (p > 0.05). The rs2237572 CDK6 genotypes were associated with the BC and affirmed that allele C was inherited as a recessive risk factor. Moreover, a highly significant difference between patients’ subtypes in the genotypic frequency of rs2237572 (p < 0.01) was noted. Furthermore, the association of rs2237572 genotypes and CDK6 serum concentration in BC patients showed a considered significant difference between C/C and T/T, C/C and T/C and the CDK6 level (p < 0.05). Nevertheless, T/T and T/C did not show any significant difference with the CDK6 level. Hence, it was concluded that the rs2237572 of CDK6 gene is significantly correlated with BC. 相似文献
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在1980－1981年对云南西双版纳克木人、基诺族、哈尼族和拉祜族四个民族青少年品德形成调查的基础上，又于2000－2001年对上述四个民族的青少年品德进行了调查及横向、纵向的比较研究。历时20年的调查研究表明，1．四个民族对青少年的品德形成具有卓有成效的共同经验：（1）榜样；（2）宗教；（3）组织；（4）舆论；（5）教育。2．四个民族对青少年的品德教育具有十分明显的实践性。3．个人的品德有相对稳定性。 相似文献
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霍涌泉 《陕西师范大学学报(哲学社会科学版)》2000,29(3):160-168
实现教育现代化是高等教育改革发展的基本思路。当前高等教育现代化的主要特征是学术创新信息化、国际化、市场化、大众化及终身化。作为履行高等教育教学职贵的大学教师,只有具备全、新、高的专家型学者的素质,才能适应知识经济时代的严峻挑战。人格动机与创新态度品质、教学专长、学术研究专长、社会服务意识和技能,是一名成功教师应该具有的核心素质指标。专家型教师是高校新型教师素质的典型代表。 相似文献
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