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| CD44smRNA在大肠癌中表达的研究 | |
| 引用本文： | 蒋丽娜,薄爱华,张晓丽,丁秀丽,苏华,陈秀玲,张江兰,杨艳君.CD44smRNA在大肠癌中表达的研究[J].河北北方学院学报(医学版),2005,22(3):12-13. |
| 作者姓名： | 蒋丽娜 薄爱华 张晓丽 丁秀丽 苏华 陈秀玲 张江兰 杨艳君 |
| 作者单位： | 1. 河北北方学院免疫教研室,河北,张家口,075000 2. 河北北方学院实验中心,河北,张家口,075000 3. 中国人民解放军第251医院中心实验室,河北,张家口,075000 4. 河北北方学院电镜室兴趣小组,河北,张家口,075000 |
| 摘 要： | 目的:探讨CD44smRNA在大肠癌细胞中表达的特点.方法:利用核酸原位杂交技术,对52例大肠癌组织进行检测.结果:CD44smRNA在大肠癌中总阳性率为65.38%(34/52)CD44smRNA表达与患者的性别、年龄及分化程度无相关性,而与有否淋巴结转移有一定的相关性.结论:CD44smRNA在大肠癌中有较高表达,可作为临床预测大肠癌转移潜能的一个重要参考指标. |
| 关 键 词： | 大肠癌 原位杂交 |
| 文章编号： | 1673-1484(2005)03-0012-02 |
The Study of CD44smRNA Expression in Large Intestine Carcenoma |
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| JIANG Li-na,BO Ai-hua,ZHANG Xiao-li,et al..The Study of CD44smRNA Expression in Large Intestine Carcenoma[J].Journal of Hebei North University:Medical Edition,2005,22(3):12-13. | |
| Authors: | JIANG Li-na BO Ai-hua ZHANG Xiao-li |
| Institution: | JIANG Li-na,BO Ai-hua,ZHANG Xiao-li,et al. Hebei North University,Zhangjiakou 075000,China |
| Abstract: | Objective:To study the expression char acter of CD44smRNAin large intestine cancer. Methods:The 52 case s of large intestine cancer were examined with in situ hybridization methods. Results:The total positive expression rate of CD44smRNA was 63.46 %(33/52) in large intestin cancer. The CD44smRNA was correlated with patient's a ge, sex and tumor differentiation(P>0.05).There was a significa nt correlation between CD44smRNA and lymph node metastasis(P<0. 05).Conclusion:There was higher expression of CD44 in large int estin cancer.The expression of CD44smRNA may serve as an indicator to predict th e lymph nodes metasis in large intestine carcinoma. |
| Keywords: | CD44smRNA |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |