| 运动疲劳与记忆——谷氨酸及受体NMDA在运动疲劳中的作用 |
| |
| 引用本文： | 刘宇,王忠梅,韩忠媛,张立丰.运动疲劳与记忆——谷氨酸及受体NMDA在运动疲劳中的作用[J].辽宁体育科技,2007,29(2):17-19. |
| |
| 作者姓名： | 刘宇 王忠梅 韩忠媛 张立丰 |
| |
| 作者单位： | 沈阳体育学院,辽宁,沈阳,110032 |
| |
| 摘 要： | 过度运动引起海马神经元机能的改变是运动性疲劳的中枢机制之一，海马突触传递效能是反映大脑功能状态的重要指标。谷氨酸是中枢神经系统中主要的兴奋性神经递质；谷氨酸受体：N-甲基-D-天冬氨酸（NMDA）受体被公认为是影响学习记忆的关键物质。海马谷氨酸及其受体的含量，是影响海马突触可垫l生的重要因素。运动中谷氨酸及NMDA受体的变化对海马突触可塑性的影响在运动疲劳的中枢机制中扮演重要角色。
|
| 关 键 词： | 运动疲劳 谷氨酸 NMDA受体 海马突触传递的长时程增强(LTP) |
| 文章编号： | 1007-6204（2007）02-0017-03 |
| 收稿时间： | 2006-11-29 |
| 修稿时间： | 2007-02-12 |
Exercise fatigue and memory-role of glutamate and glutamate receptor NMDA in exercise fatigue |
| |
| LIU Yu,WANG Zhong-mei,HAN Zhong-yuan,ZHANG Li-feng.Exercise fatigue and memory-role of glutamate and glutamate receptor NMDA in exercise fatigue[J].Liaoning Sport Science and Technology,2007,29(2):17-19. |
| |
| Authors: | LIU Yu WANG Zhong-mei HAN Zhong-yuan ZHANG Li-feng |
| |
| Institution: | LIU Yu, WANG Zhong-mei, HAN Zhong-yuan,ZHANG Li-feng (Shenyang Institute of Physical Education, Shenyang Liaoning 110032 ) |
| |
| Abstract: | Functional transform of the hippocampus neure due to overexercise, is one of the central mechanism of exercise fatigue. Synaptic transmission activity on hippocampus is an important index to reflect brain functional condition. Glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamate receptor --it is reputed N-methyl-D-aspartate receptor, is the key substance of learning and memory. The content of glutamate and glutamate receptors is a primary factor to effect synaptic plasticity in the hippocampus. The effects of synaptic plasticity caused changes of Glutamate and NMDA receptor during exercise play an important role in the central mechanism of exercise fatigue. |
| |
| Keywords: | Exercise Fatigue Glutamate NMDA receptor Long-term potentiation of hippocampal synaptic transmission (LTP) |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
