| 抗精子抗体检测诊断不孕症的临床价值 |
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| 引用本文： | 裘红梅,宋光,于增国,王笑虹.抗精子抗体检测诊断不孕症的临床价值[J].大连大学学报,2006,27(2):88-90. |
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| 作者姓名： | 裘红梅 宋光 于增国 王笑虹 |
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| 作者单位： | 大连大学,医学院,辽宁,大连,116622 |
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| 摘 要： | 目的:检测不孕症和患者血清中抗精子抗体含量(包括总的抗精子抗体,抗精子抗体的IgG和IgA型)并计算出不孕症患者血清中抗精子抗体的阳性率.方法:采用酶联免疫吸附试验(ELISA)的方法检测76例不孕症患者及70例正常生育对照组血清中的抗精子抗体.结果:不孕症患者组血清中抗精子抗体阳性率为28.94%,明显高于正常生育者(抗精子抗体的阳性率为5.7%,P<0.01)并且,以IgG型抗体增高明显,IgA型抗体无显著性差异.结论:抗精子抗体是免疫性不孕的重要因素,ELISA方法定量检测抗精子抗体IgG型对诊断不孕症有一定价值.
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| 关 键 词： | 不孕症 抗精子抗体 ELISA |
| 文章编号： | 1008-2395（2006）02-0088-03 |
| 收稿时间： | 2004-11-03 |
| 修稿时间： | 2004年11月3日 |
Diagnostic value of examining the level of AsAb-IgG |
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| QIU Hong-mei,SONG Guang,YU Zeng-guo,WANG Xiao-hong.Diagnostic value of examining the level of AsAb-IgG[J].Journal of Dalian University,2006,27(2):88-90. |
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| Authors: | QIU Hong-mei SONG Guang YU Zeng-guo WANG Xiao-hong |
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| Abstract: | objective] To examine the level of total AsAb,AsAb-IgG and AsAb-IgA in serum with infertility,and counting the positive rate of AsAb in serum with infertility.Menthod] ELISA was applied to determine the AsAb in serum samples of 76 patients with infertility and that of 70 normal pregnant history group.Results] The level of AsAb in serum with infertility was significantly higher than that of normal pregnant history group.The positive rate of AsAb in serum with infertility was 28.94%,and the positive rate of AsAb in serum with normal pregnant history group was 5.7%,and AsAb-IgG was on increase obviously in serum with infertility.Conclusion] The examination of the level of AsAb was an important factor for immune infertility by ELISA menthod.The examination of the level of AsAb-IgG was very significant for the diagnose of the infertility patients. |
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| Keywords: | infertility AsAb ELISA |
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