| 家鸽左心室流出道电生理特性的观察 |
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| 引用本文： | 焦宏,陈彦静,马建伟.家鸽左心室流出道电生理特性的观察[J].河北北方学院学报(医学版),2003,20(5):27-29. |
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| 作者姓名： | 焦宏 陈彦静 马建伟 |
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| 作者单位： | 张家口医学院生理教研室,075000 |
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| 基金项目： | 河北省自然基金资助项目NO:30 0 379 |
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| 摘 要： | 目的 :探讨 4-AP对家鸽左心室流出道组织动作电位的影响。方法 :利用细胞内微电极记录技术 ,观察 1 2例家鸽左心室流出道组织的电生理特征 ,以分析 4 -AP对家鸽左心室流出道的作用。结果 :在局部组织记录到典型的慢反应动作电位 ;用 2mmol/L 4 -AP灌流后 ,慢反应电位RP、APA、Vmax均明显下降 (P <0 .0 5) ,而APD、APD90 也显著延长 ;APD50 无明显改变 (P >0 .0 5)。结论 :家鸽左心室流出道组织不同于普通心室肌组织 ;4-AP对家鸽左心室流出道组织慢反应动作电位去极和复极离子流有明显抑制作用
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| 关 键 词： | 4-AP 左心室流出道 电生理 慢反应电位 |
| 文章编号： | 1005-8796(2003)05-27-03 |
The Study of the Electro-physiological Characters of the Left Ventricular Outflow tract in pigeons |
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| Jiao Hong,Chen Yanjing,Ma Jianwei Zhangjiakou Medical College,Zhangjiakou ,China.The Study of the Electro-physiological Characters of the Left Ventricular Outflow tract in pigeons[J].Journal of Hebei North University:Medical Edition,2003,20(5):27-29. |
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| Authors: | Jiao Hong Chen Yanjing Ma Jianwei Zhangjiakou Medical College Zhangjiakou China |
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| Institution: | Jiao Hong,Chen Yanjing,Ma Jianwei Zhangjiakou Medical College,Zhangjiakou 075000,China |
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| Abstract: | Objective: To study the effect of 4-AP on the le ft ventricular outflo w tract in pigeons. Methods: Intracellar microelectrode record t echnology was ap plied to observe the electro-physiological characters of the tissues in the left ventricular outflow tract in 12 cases of isolated pigeons,in order to study th e effect of 4-AP. Results: typical slow action potential was re corded in local tissues .After admistrated by 2mmol/L 4-AP, the RP,APA,Vmax obviously decreased (P<0.05),but the APD and APD90 were prolonged significantly. The APD50 had no si gnificant change(P>0.05). Conclusion: The tissue s of the left ventricular outflo w tract of pigeons are different from the typical ventricular tissues. It appear s that 4-AP can inhibit the repolarizing and depolarizing current of the tissues of the left ventricular outflow tract of pigeons. |
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| Keywords: | AP left ventricular outflow tract electricalphysiolo gy slow action potential |
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