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不同形式的运动对生长期大鼠下肢骨纵向生长的影响
引用本文:鲍丽颖,王佩云.不同形式的运动对生长期大鼠下肢骨纵向生长的影响[J].天津体育学院学报,2003,18(3):63-65.
作者姓名:鲍丽颖  王佩云
作者单位:1. 天津中医学院,天津,300192
2. 天津体育学院,天津,300381
摘    要:目的:通过比较不同形式的运动训练对生长期大鼠血清及胫骨IGF—Ⅰ水平的影响,进而探讨运动影响骨生长发育的可能机理,同时为青少年选择合理的身高助长运动处方提供一定理论依据。方法:采用4周龄雌性Wistar大鼠,各运动组分别进行9周跑台、跳跃、游泳训练,检测下列指标:1.胫骨、股骨长度;2.血清IGF-Ⅰ水平;3.胫骨TGF—Ⅰ水平。结果:跑组、跳组大鼠下肢骨长度明显大于游泳组和对照组;各训练组血清IGF—Ⅰ水平与对照组相比均无显著性差异;跑组、跳组胫骨IGF-Ⅰ水平明显高于对照组和游泳组。结论:本实验采用的跑台、跳跃训练明显促进下肢骨纵向生长:血清IGF-Ⅰ水平相对稳定,受运动训练影响不明显;骨组织IGF—Ⅰ水平受运动训练影响显著。本研究结果提示运动中下肢骨承重及受力大小与其纵向生长有关,运动可引起骨组织IGF—Ⅰ水平升高,骨中IGF—Ⅰ水平可能是影响骨生长的重要因素。

关 键 词:胰岛素样生长因子-Ⅰ  运动  骨生长
文章编号:1005-0000(2003)02-0000-00
修稿时间:2002年9月17日

Effect of Different Kinds of Training on the Longitudinal Growth of Limbs Bone in Growing Rat
BAO Li-ying and WANG Pei-yun.Effect of Different Kinds of Training on the Longitudinal Growth of Limbs Bone in Growing Rat[J].Journal of Tianjin Institute of Physical Education,2003,18(3):63-65.
Authors:BAO Li-ying and WANG Pei-yun
Institution:BAO Li-ying 1,WANG Pei-yun 2
Abstract:Purpose:To investigate the changes of the lengths of tibia and femur,serum IGF-I level and bone IGF-I level after sports training.Fur-thermore to explain the reasons of the changes.Methods:The4weeks old female Wistar were randomized into four groups:control group,running group,jumping group and swimming group.Experiment duration was nine weeks.Their blood and bone were detected:1.the length of tibia and fe-mur;2.the serum IGF-I level;3.the bone IGF-I level.Results:The lengths of tibia and femur in running group and jumping group were significant longer than those in swimming group and control group.There was no significant difference in the serum IGF-I level of four groups.In running group and jumping group the tibia IGF-I level were significantly higher than those in swimming group and control group.Conclusion:The effect of exercise promoting longitudinal growth of bone was significant.Serum IGF-I level was not significantly influenced by exercise.Bone IGF-I level was affected significantly by exercise.We speculated that force be key to the elevation of bone IGF-I level.And IGF-I was an important factor to bone longitudinal growth.
Keywords:IGF-I  exercise  bone growth
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