A biochemical study on variability of Superoxide dismutase,Catalase and Glutathione peroxidase in dry cleaners |
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| Authors: | S Anbhazhagan Santosh S Winkins |
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| Institution: | (1) Department of Biochemistry, Mohamed Sathak College of Arts and Science, Sholinganallur, Chennai, India;(2) Department of Biotechnology, SRM University, Kattankulathur, 603203, India |
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| Abstract: | Several chemicals which induce cytotoxicity are broadly classified into three types and they are organophosphate, organochlorine
and carbomate compounds. Perchloroethylene has been clearly identified as a carcinogen in experimental animals and it’s a
very common carcinogen used for dry clean purpose. Hence, in the present study, blood samples from dry cleaners were taken,
Superoxide dismutase, Catalase and Glutathione peroxidase activity was estimated in blood samples of dry cleaners. There was
a significant increase in the activity of Catalase, Glutathione Peroxidase, Superoxide Dismutase in dry cleaners of chronically
exposed to perchloroethylene as compared to controls. The increased activities of antioxidant enzymes may be a compensatory
regulation in response to increased oxidative stress induced by perchloroethylene. |
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| Keywords: | Perchloroethylene Antioxidant enzymes Dry cleaners Catalase Glutathione Peroxidase Superoxide Dismutase |
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