| 合成生物学:开启生命科学“会聚”研究新时代 |
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| 引用本文： | 赵国屏.合成生物学:开启生命科学“会聚”研究新时代[J].中国科学院院刊,2018,33(11):1135-1149. |
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| 作者姓名： | 赵国屏 |
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| 作者单位： | 中国科学院上海生命科学研究院 生物医学大数据中心 上海 200031;中国科学院植物生理生态研究所 合成生物学重点实验室 上海 200032 |
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| 摘 要： | 自然科学各学科的研究对象在时空尺度上的差别与相连,既决定了学科间的差别,也决定了学科间的交叉。生物学在发展到以机理研究为主的"生命科学"阶段后,得益于学科交叉和技术创新,在20世纪"分子生物学"和"基因组学"革命基础上,通过引入工程学理念,形成了"合成生物学",并迅速形成"会聚研究"的第三次革命。文章在阐述合成生物学的内涵并回顾其学科发展历程与取得成果的基础上,特别提出了合成生物学的科技支撑与社会治理问题,期望引起科学界、社会公众与政府管理层面的关注。
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| 关 键 词： | 学科交叉 生命科学 工程学 分子生物学 社会治理 |
| 收稿时间： | 2018/10/28 0:00:00 |
Synthetic Biology: Unsealing the Convergence Era of Life Science Research |
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| ZHAO Guoping.Synthetic Biology: Unsealing the Convergence Era of Life Science Research[J].Bulletin of the Chinese Academy of Sciences,2018,33(11):1135-1149. |
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| Authors: | ZHAO Guoping |
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| Institution: | Biomedical Big Data Center, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China;Key Laboratory of Synthetic Biology, Institute of Plant Physiology & Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China |
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| Abstract: | It is their distinct spatial and temporal scales for natural substances defined various kinds of disciplines of natural sciences, as well as their connections. Based on the disruptive advances attributable to the revolutions of Molecular Biology and Genomics in the 20th century, by introducing the principles of engineering science into life science and biotechnology, the third revolution of Convergence has been emerged and rapidly developed into the cutting-edge frontier of academic research since the beginning of this century. The serial review articles of this issue illustrated both the history and the connotations of synthetic biology via highlighting main fields of research for synthetic biology, especially their scientific and technological fundamentals and social governance issues, thus it may cause attentions from the academic, the public and governments. |
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| Keywords: | crossdisciplinarity life science engineering molecular biology societal governance |
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