| Science Letters:Brain metastases of melanoma-mechanisms of attack on their defence system by engineered stem cells in the microenvironment |
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| 作者姓名： | DIMITROV Borislav D. ATANASSOVA Penka A. RACHKOVA Mariana I. |
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| 作者单位： | BORDANI Alzano Lombardo Bergamo 24022 Italy，Department of Neurology Medical University Plovdiv 4000 Bulgaria，ASSON-93 Research Co. Chicago IL 60056 USA |
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| 摘 要： | This report gives a better emphasis on the role of targeted effectors (e.g. a combination of 5-FC with CD-NSPCs as compared to the application of NSPCs alone) and how such delivery of pro-drug activating enzymes and other tumor-killing substances may overcome melanocytic defence system, interact with and promote the host defence and immune response modulations not only in melanoma but, potentially, in other highly-metastatic cancers.
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