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畜牧业发展中抗菌药应用的“利”与“刃”
引用本文:于洋,方亮星,周宇峰,孙坚,廖晓萍,刘雅红.畜牧业发展中抗菌药应用的“利”与“刃”[J].中国科学院院刊,2019,34(2):152-162.
作者姓名:于洋  方亮星  周宇峰  孙坚  廖晓萍  刘雅红
作者单位:华南农业大学兽医学院
基金项目:“十三五”国家重点研发计划项目(2016YFD0501300)
摘    要:长期以来,抗菌药为畜牧业的健康发展一直起着保驾护航的重要作用,并且在将来较长时期内,抗菌药仍是集约化养殖业防治细菌病的主要手段。但随着抗菌药在养殖业的广泛使用,耐药菌的出现有可能使人类重新回到对多种感染无药可用的"前抗生素"黑暗时代,抗菌药的耐药性逐渐发展成为全球面临的挑战性问题。鉴于此,文章主要讨论抗菌药给畜牧业养殖所带来的正面影响,以及抗菌药使用所引发的全球耐药性问题,并针对我国国情提出关于抗菌药物应用和耐药性监管的策略、建议及面临的风险。

关 键 词:抗菌药  畜禽养殖  利弊  耐药性风险  监管
收稿时间:2019/2/3 0:00:00

Benefit and Risk of Utilizing Antimicrobials in Animal Husbandry Development
YU Yang,FANG Liangxing,ZHOU Yufeng,SUN Jian,LIAO Xiaoping and LIU Yahong.Benefit and Risk of Utilizing Antimicrobials in Animal Husbandry Development[J].Bulletin of the Chinese Academy of Sciences,2019,34(2):152-162.
Authors:YU Yang  FANG Liangxing  ZHOU Yufeng  SUN Jian  LIAO Xiaoping and LIU Yahong
Institution:College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China,College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China,College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China,College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China,College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China and College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China
Abstract:For decades, antimicrobials have played a key role in helping and protecting the sound development of animal husbandry. Undoubtedly, for intensive farming, antibiotics will still be one of the essential strategies for preventing and treating the bacterial infectious disease in a very long time. Nevertheless, due to the widely use of antimicrobials, the resistant bacteria and antimicrobial resistance have emerged, which become a severe challenge threatening the whole public for returning to the "pre-antibiotic era". For comprehensively understanding of this issue, here this study focuses on the pros and cons of using antibiotics in livestock, global experience in balancing the use of drugs and the control of antimicrobial resistance, and the advices and strategies are raised specifically for China.
Keywords:antimicrobials  livestock and poultry farming  benefit and risk  antimicrobial resistance  supervision and management
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