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| EPO在老年重度慢性心力衰竭伴贫血患者中的应用 | |
| 引用本文： | 李天民,赵九安,刘军玺,郑学军,李瑞娟.EPO在老年重度慢性心力衰竭伴贫血患者中的应用[J].河北北方学院学报(医学版),2007,24(5):3-5. |
| 作者姓名： | 李天民 赵九安 刘军玺 郑学军 李瑞娟 |
| 作者单位： | 1. 河北北方学院附属第一医院老年病科,河北,张家口,075000 2. 河北北方学院附属第一医院心内科,河北,张家口,075000 3. 中国人民解放军第251医院老年病科,河北,张家口,075000 4. 河北省张家口市第六医院耳鼻喉科,河北,张家口,075000 |
| 基金项目： | 河北省卫生厅医学科研项目 |
| 摘 要： | 目的:探讨促红细胞生成素(EPO)在重度慢性心力衰竭(chronic heart faiture,CHF)伴贫血的患者中应用的有效性。方法:选择自2004.8～2005.8月间住院的重度CHF(心功能Ⅲ～Ⅳ级)伴贫血的患者,采用前瞻性队列研究,随机分为治疗组和对照组,两组患者均给予常规抗心衰治疗,治疗组加用重组促红细胞生成素(rhEPO)注射及铁剂口服治疗,随访1年,比较两组在客观指标上的差别。结果:两组患者在心脏射血分数(LVEF)、6min步行距离及死亡率上均有明显差异。结论:在常规控制心衰治疗的基础上,给予EPO抗贫血干预,可延缓重度CHF伴贫血患者的病情进展,降低死亡率。 |
| 关 键 词： | 慢性心力衰竭 促红细胞生成素 贫血 |
| 文章编号： | 1674-1484（2007）05-0003-03 |
Application of EPO in Old Patients with Serious Chronic Heart Failure Accompanied by Anemia |
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| LI Tian-min, ZHAO Jiu-an, LIU Jun-xi, et al.Application of EPO in Old Patients with Serious Chronic Heart Failure Accompanied by Anemia[J].Journal of Hebei North University:Medical Edition,2007,24(5):3-5. | |
| Authors: | LI Tian-min ZHAO Jiu-an LIU Jun-xi |
| Institution: | The First Affiliated Hospital, Hebei North University, Zhangjiakou, 075000 ,Hebei, China |
| Abstract: | Objective:To explore the applied effectiveness of EPO in patients with serious CHF accompanied by amenia.Methods:Cases were selected from patients with serious CHF accompanied by anemia,hospitalized between 2004 Augest and 2005 Augest,and divided at random into treatment group and control group;forward-looking filing was adopted.Two groups were both rendered regular anti-heart failure treatment;control group was added injection of Rh-EPO and ferrous obiect;after one year follow-up,difference in objective indices was compared.Results:There was significant difference between two groups in LVEF,6-minute walking distance and death rate.Conclusion:On basis of regular treatment of anti-heart failure,intervention of EPO against anemia could delay progress of serious CHF accompanied by anemia and even lower death rate. |
| Keywords: | CHF EPO Anemia |
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